Oklahoma State vs Kansas Prediction 11/1/25 College Football Picks Today

In this article, we will formulate an Oklahoma State vs Kansas Prediction for this College Football Week 10 game on Saturday, November 1^st. Let’s take a look at the prediction for this College Football matchup.

Kansas Jayhawks Preview

Kansas has a 4-4 record this season and is sitting 10th in the Big 12. They are 3-5 ATS, 4-4 in Over/Under and have a 3-2 home record and a 1-2 away record. Kansas is coming off a 17-42 home loss against Kansas State and will face Arizona, Iowa State and Utah next.

Offensively, Kansas averages 30.5 points per game, ranking 56th in the nation, while defensively, they allow 25.9 points per game, which is 84th. Kansas averages 396.9 total yards per game (247.5 passing and 149.4 rushing), while allowing 391.4 total yards per game (182.3 rushing and 209.1 passing).

Jalon Daniels leads Kansas with 1,881 passing yards with 66.5% completed passes and 18 touchdowns. Leshon Williams leads the team in rushing yards with 314, while Emmanuel Henderson has a team-high 34 receptions for 554 receiving yards. Defensively, Trey Lathan has a team-high 54 total tackles (33 of them solo), while Leroy Harris III leads the team in sacks, with 4.5. Trey Lathan, Lyrik Rawls, Taylor Davis and Devin Dye lead the team with one interception each.

Oklahoma State Cowboys Preview

Oklahoma State has a 1-7 record this season and is sitting 16th in the Big 12. They are 1-7 ATS, 4-4 in Over/Under and have a 1-4 home record and a 0-3 away record. Oklahoma State is coming off a 0-42 road loss against Texas Tech and will face Kansas State, UCF and Iowa State next.

Offensively, Oklahoma State averages 14.5 points per game, ranking 132nd in the nation, while defensively, they allow 38.9 points per game, which is 135th. Oklahoma State averages 295.4 total yards per game (161.6 passing and 133.8 rushing), while allowing 456.5 total yards per game (161.8 rushing and 294.8 passing).

Zane Flores leads Oklahoma State with 696 passing yards with 55.0% completed passes and 0 touchdowns. Rodney Fields Jr. leads the team in rushing yards with 420, while Gavin Freeman has a team-high 29 receptions for 280 receiving yards. Defensively, Parker Robertson has a team-high 51 total tackles (30 of them solo), while Wendell Gregory leads the team in sacks, with 3.0, and LaDainian Fields leads the team with 1 interception.

Oklahoma State Cowboys @ Kansas Jayhawks Betting Trends: Week 10

Why the Kansas Jayhawks will win

• Oklahoma State has lost each of its last 15 games against conference opponents.
• The favorite has won 13 of Oklahoma State’s last 14 games.
• Oklahoma State has failed to cover the spread in 12 of its last 13 games.
• The favorite has covered the spread in each of Oklahoma State’s last four games.
• Oklahoma State has lost the first half in each of its last nine games against conference opponents.

Why the Oklahoma State Cowboys will win

• Kansas has lost each of its last seven November home games against non-AP-ranked teams.
• The road team has won three of Kansas’ last four games.
• Oklahoma State has covered the spread in eight of its last nine games against Kansas.
• Kansas has failed to cover the spread in six of its last seven November home games against non-AP-ranked teams.
• Kansas has lost the first half in each of its last four games against conference opponents.

Total Points Facts

• Ten of Oklahoma State’s last 11 road games in November have gone UNDER the total points line.
• Eight of Kansas’ last 10 games in Kansas have gone UNDER the total points line.

Kansas Jayhawks Player Prop Facts

• Heading into Week 10, Leshon Williams leads Kansas for touchdowns (7) this season.

Oklahoma State Cowboys Player Prop Facts

• Heading into Week 10, Zane Flores has the most pass attempts without a passing touchdown this season (140).

Matchup/League Facts

• Kansas is one of only five FBS teams with 100% success rate on field goals and extra points this season.
• Kansas is one of only eight FBS teams with 100% success rate on field goals this season.
• Oklahoma State ranks 136th among FBS teams for H1 opponent points per game this season (24.5).
• Oklahoma State ranks 136th among FBS teams for average point differential in first quarters this season (-7.4).

Oklahoma State vs Kansas Prediction

In their previous meeting in 2023, Oklahoma State won 39-32 at home and are 9-1 in their last 10 meetings against Kansas. Over is 6-3 in their last 9 meetings.

In this Oklahoma State vs Kansas Prediction, Kansas is coming as -24.5-point home favorites, with the total set at 57.5 points. Oklahoma State has been terrible this season with just one win in 8 games played and are also terrible against the spread with a 1-7 record. I don’t trust Kansas a huge home favorites, as they are 1-3 both straight up and against the spread in their last 4 games. Kansas has the 56^th-best offense in the country, going up against the second-worst defense, so I expect a high-scoring affair today. Take the over 57.5 points in this one.