Oregon State vs Oregon Prediction 9/20/25 College Football Picks Today

In this article, we will formulate an Oregon State vs Oregon Prediction for this College Football Week 4 game on Saturday, September 20^th at the Autzen Stadium. Let’s take a look at the prediction for this College Football matchup.

Oregon Preview

Oregon has a 3-0 record this season and are coming off a 34-14 road victory in Northwestern. Offensively, the Ducks average 54.0 points per game, which ranks 4th in the nation. Defensively, they allow 10.0 points per game, which ranks 16th in the nation. Oregon averages 503.3 total yards per game, with 247.0 rushing yards and 256.3 passing yards per game. They allow 256.0 total yards per game, 122.7 of them rushing and 133.3 passing yards per game.

Dante Moore leads the Ducks with 50/64 completed passes and 657 total passing yards. He also adds 34 rushing yards. Dierre Hill Jr leads the team in rushing yards, with 161 and 2 touchdowns, while Noah Whittington adds 159 rushing yards and 2 touchdowns. Malik Benson has a team-high 11 caught passes for a team-high 161 receiving yards, and has 2 touchdowns. Dakorien Moore has caught 9 passes for 144 yards, and 1 touchdown.

Defensively, Bryce Boettcher has a team-high 17 total tackles, 4 of them solo. Matayo Uiagalelei leads the Ducks in sacks, with 3, while Jerry Mixon has a team-high 2 interceptions, and Bryce Boettcher and Peyton Woodyard each have 1 interception.

Oregon State Preview

Oregon State has a 0-3 record this season and are coming off a 14-45 road defeat in Texas Tech. Offensively, Oregon State averages 18.7 points per game, which ranks 117th in the nation. Defensively, they allow 38.3 points per game, which ranks 129th in the nation. Oregon State averages 376.7 total yards per game, with 71.0 rushing yards and 305.7 passing yards per game. They allow 424.3 total yards per game, 146.7 of them rushing and 277.7 passing yards per game.

Maalik Murphy leads the Beavers with 77/125 completed passes and 896 total passing yards. He also adds -20 rushing yards and 1 touchdown. Anthony Hankerson leads the team in rushing yards, with 190 and 1 touchdown, while Salahadin Allah adds 36 rushing yards. Jaden Robinson has a team-high 16 caught passes for a team-high 211 receiving yards, and has 1 touchdown. Isaiah Newell has caught 12 passes for 136 yards.
Defensively, Dexter Foster has a team-high 25 total tackles, 7 of them solo. Skyler Thomas adds 23 total tackles, 10 of them solo and 1 interception. Tahjae Mullix leads the Beavers in sacks, with 1, while Skyler Thomas, Harlem Howard and Jailil Tucker each have 1 interception.

Oregon State Beavers @ Oregon Ducks Betting Trends: Week 4

Why the Oregon Ducks will win

• Oregon has won each of its last 41 games against non-AP-ranked teams at Autzen Stadium.
• Oregon State has lost each of its last nine games against non-conference opponents.
• Oregon State has failed to cover the spread in nine of its last 10 games against non-conference opponents.
• Oregon has covered the spread in six of its last seven home games in September.
• Oregon has won the first half in 21 of its last 22 games against non-conference opponents at Autzen Stadium.
• Oregon has won the first quarter in each of its last 14 games against non-conference opponents at Autzen Stadium.

Why the Oregon State Beavers will win

• The team ranked 6th in the AP Poll has failed to cover the spread in four of its last five games.
• The road team has covered the spread in three of Oregon State’s last four games.

Total Points Facts

• Each of Oregon’s last four games against non-conference opponents have gone OVER the total points line.
• Four of Oregon State’s last five games against opponents from the Big Ten Conference have gone OVER the total points line.

Oregon Ducks Player Prop Facts

• Heading into Week 4, Dante Moore ranks 4th amongst qualified players for passer rating (139.4) this season.

Oregon State Beavers Player Prop Facts

• Heading into Week 4, Trent Walker leads the Pac-12 Conference for receptions (23) this season.

Matchup/League Facts

• Oregon ranks 1st among FBS teams for Q3 points per game this season (18.7).
• Oregon ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
• Oregon State ranks 133rd among FBS teams for average point differential in first quarters this season (-9.7).
• Oregon State ranks 132nd among FBS teams for rushing yards per game this season (71.0).

Oregon State vs Oregon Prediction

In their previous meeting last season, Oregon won 49-14 on the road, covering the spread, as the game went over the point total. Oregon is 6-2 in their last 8 head-to-head meetings against Oregon State, and have won their last five home meetings against the Beavers. Over is 4-1 in their last 5 meetings.

In this Oregon State vs Oregon Prediction, Oregon is coming as -35-point home favorites. Those two teams have started the season in completely opposite directions, as Oregon has been undefeated and 2-1 ATS, while Oregon State is winless and have failed to cover the spread in all of their three games this season. Oregon is the superior team in this matchup, and has been dominating the Beavers at home, so I like them to get away with a comfortable win today and cover the -35-point spread.