College Football

Oregon vs UCLA Prediction Football Picks Today 10/10/26

UCLA Bruins (4-0) vs. Oregon Ducks (3-1)
October 10, 2026 3:30 pm EDT
The Line: Oregon Ducks -455 / UCLA Bruins 350; Over/Under: 59.5
(Get latest betting odds)

In this article we will formulate an Oregon vs UCLA prediction for this College Football game on Saturday, October 10th at Autzen Stadium in Eugene, Oregon. Let’s take a look at the prediction for this Week 6 matchup. 

Oregon Ducks Betting Preview

The Oregon Ducks are 3-1 (1-0) this season after they defeated USC by a score of 41-27 in their last game. Oregon led 13-10 at halftime and they scored 28 points in the second half to seal the win, despite their starting QB getting hurt. The Ducks out gained USC by a total of 504-446, went 6-12 on third downs, and won the turnover battle by a total of 1-0 in the game. Dylan Raiola threw for 289 yards and two touchdowns, while Jamari Johnson caught seven passes for 119 yards. Jordon Davison rushed 16 times for 66 yards and one score in the win. 

Prior to that game, Oregon defeated Portland State by a score of 84-0, but lost to Oklahoma State by a score of 39-31 before that. The Ducks have scored 47.5 points per game with 346.5 passing yards and 159.0 rushing yards per game, while they have allowed 23.3 points against per game this season. Dylan Raiola will start for the injured Dante Moore at the quarterback spot. 

UCLA Bruins Betting Preview

The UCLA Bruins are 4-0 (2-0) this year after they defeated Maryland by a score of 54-3 in their last game. UCLA led 20-3 at halftime and they won the second half 34-0 for the blowout win. The Bruins out gained Maryland by a total of 475-181, went 2-10 on third downs, and won the turnover battle by a total of 5-2 in the game. Nico Iamaleava threw for 209 yards and one touchdown, while Aidan Mizell caught one pass for 83 yards and one score. Wayne Knight rushed 10 times for 100 yards and one touchdown in the win. 

Prior to that game, UCLA defeated Purdue by a score of 52-38 and San Diego State by a score of 28-10. The Bruins have scored 44.8 points per game with 205.0 passing yards and 281.5 rushing yards per game, while they have allowed 18.8 points against per game this season. Nico Iamaleava has thrown for 820 yards with four touchdowns and two interceptions, while Wayne Knight has rushed 49 times for 445 yards and nine scores this year. 

Why the Oregon Ducks will win

  • Oregon has won each of its last 11 games against teams from California.
  • UCLA has lost each of its last 10 road games against AP-ranked teams.
  • Oregon has covered the spread in eight of its last nine October games as a favorite against AP-ranked teams.
  • UCLA has failed to cover the spread in each of its last four games as an AP-ranked team against an AP-ranked team.
  • Oregon has won the first quarter in each of its last five games against teams from California.
  • UCLA has lost the first half in each of its last 12 road games against top-15 AP-ranked teams.

Why the UCLA Bruins will win

  • The team ranked 21st in the AP Poll has won 12 of its last 13 games.
  • UCLA has covered the spread in each of its last five games.
  • The team ranked 13th in the AP Poll has failed to cover the spread in four of its last five games.
  • The road team has won the first quarter in three of Oregon’s last four games.
  • The team ranked 21st in the AP Poll has won the first half in four of its last five games.

Total Points Facts

  • Nine of UCLA’s last 10 October games as an underdog against top-15 AP-ranked teams have gone OVER the total points line.
  • Seven of Oregon’s last eight games as a favorite have gone OVER the total points line.

Oregon Ducks Player Prop Facts

  • Heading into Week 6, Dante Moore ranks 9th amongst qualified players for passer rating (178.3) this season.

UCLA Bruins Player Prop Facts

  • Heading into Week 6, Ta’Shawn James ranks T2nd amongst FBS players for interceptions (3) this season.

Matchup/League Facts

  • Oregon has won the third quarter in each of its last six games – longest active streak in the FBS.
  • Oregon ranks T1st among FBS teams for red zone percentage this season (100.0).
  • UCLA ranks 1st among FBS teams for Q4 points per game this season (19.0).
  • UCLA ranks 1st among FBS teams for H2 points per game this season (27.8).

Oregon vs UCLA Prediction

Oregon comes into this matchup with the home field advantage and they probably have the best backup quarterback in the country, so the loss of Moore isn’t too big. UCLA is off to a great start, but this will be their first test. The Bruins have scored 45+ points in three of their last four games, but did allow 38 to Purdue two games ago. UCLA has been a great story, but I don’t think they matchup very well here. Take Oregon to win big at home. 

David Racey's Free Pick: Oregon -11.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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