Wyoming Cowboys (4-4) vs. San Diego State Aztecs (6-1)
November 1, 2025 7:00 pm EDT
The Line: San Diego State Aztecs -10 / Wyoming Cowboys 10; Over/Under: 42.5
(Get latest betting odds)
The Wyoming Cowboys and San Diego State Aztecs meet Saturday in college football action at Snapdragon Stadium. Here’s a San Diego State vs Wyoming Prediction. This article will include a San Diego State vs Wyoming Pick.
Wyoming Cowboys Betting Preview
The Wyoming Cowboys beat Colorado State, lost to Air Force and plays Fresno State next. Wyoming has split its last 8 games. Kaden Anderson is completing 59.6 percent of his passes for 1,635 yards, 11 touchdowns, and 6 interceptions. Chris Durr Jr. and John Jaylen Sargent have combined for 624 receiving yards and 4 touchdowns, while Samuel Harris has 14 receptions.
The Wyoming Cowboys ground game is averaging 157.3 yards per contest, and Samuel Harris leads the way with 430 yards and 1 touchdown. Defensively, Wyoming is allowing 19.8 points and 342.8 yards per game. Brayden Johnson leads the Wyoming Cowboys with 48 tackles, Ben Florentine has 5 sacks and Desman Hearns has 2 interceptions.
San Diego State Aztecs Betting Preview
The San Diego State Aztecs beat Nevada and Fresno State, and they play Hawaii next. San Diego State has won 5 straight games. Jayden Denegal is completing 64.8 percent of his passes for 1,221 yards, 7 touchdowns, and 3 interceptions. Donovan Brown and Jordan Napier have combined for 776 receiving yards and 3 touchdowns, while Jacob Bostick has 11 receptions.
The San Diego State Aztecs ground game is averaging 184.1 yards per contest, and Lucky Sutton leads the way with 662 yards and 7 touchdowns. Defensively, San Diego State is allowing 10.4 points and 255.7 yards per game. Owen Chambliss leads the San Diego State Aztecs with 57 tackles, Trey White has 4 sacks and Chris Johnson has 3 interceptions.
Why the San Diego State Aztecs will win
- Wyoming has lost each of its last eight games in California.
- San Diego State has won each of its last five games.
- The favorite has covered the spread in eight of San Diego State’s last nine games.
- Wyoming has failed to cover the spread in five of its last six games in California.
- San Diego State has won the first quarter in four of its last five games against conference opponents.
- San Diego State has won the first half in each of its last three games against conference opponents.
Why the Wyoming Cowboys will win
- San Diego State has lost nine of its last 10 games in November.
- Wyoming has won four of its last five November games against non-AP-ranked teams.
- San Diego State has failed to cover the spread in six of its last seven November games as a favorite.
- Wyoming has covered the spread in four of its last five games against conference opponents.
Total Points Facts
- Each of San Diego State’s last seven November games as a home favorite have gone UNDER the total points line.
- Five of Wyoming’s last six games against conference opponents have gone UNDER the total points line.
San Diego State Aztecs Player Prop Facts
- Heading into Week 10, Lucky Sutton leads San Diego State for touchdowns (7) this season.
Wyoming Cowboys Player Prop Facts
- Heading into Week 10, Desman Hearns leads the Mountain West Conference for forced fumbles (2) this season.
Matchup/League Facts
- San Diego State ranks 2nd among FBS teams for points allowed per game this season (10.4).
- San Diego State ranks 4th among FBS teams for H1 opponent points per game this season (4.6).
- Wyoming ranks T126th among FBS teams for Q2 points per game this season (4.6).
- Wyoming ranks 126th among FBS teams for H1 points per game this season (8.5).
San Diego State vs Wyoming Prediction
On paper, San Diego State should roll in this spot, but it’s just 2-7 ATS in its last 9 games as a double-digit favorite. Wyoming has been more competitive than its record and is 5-3 ATS on the season. Wyoming has a bend but don’t break defense and has shown flashes offensively as of late. Wyoming has covered 9 of its last 12 games as a double-digit underdog. Wyoming is a scrappy bunch that’s competing and could find a way to hang in this game as well. I’ll take a shot with the points.
