Duke Blue Devils (1-1) vs. Tulane Green Wave (2-0)
September 13, 2025 8:00 pm EDT
The Line: Tulane Green Wave -2 / Duke Blue Devils 2; Over/Under: 54.5
(Get latest betting odds)
The Duke Blue Devils and Tulane Green Wave meet Saturday in college football action at Yulman Stadium. Here’s a Tulane vs Duke Prediction. This article will include a Tulane vs Duke Pick.
Duke Blue Devils Betting Preview
The Duke Blue Devils beat Elon, lost to Illinois, and they play NC State next. Duke has won 5 of its last 6 regular season games. Darian Mensah is completing 73.5 percent of his passes for 723 yards, 5 touchdowns, and 1 interception. Cooper Barkate and Que’Sean Brown have combined for 315 receiving yards on 16 catches, while Andrel Anthony has 9 receptions.
The Duke Blue Devils ground game is averaging 120.5 yards per contest, and Anderson Castle leads the way with 80 yards on 7 carries. Defensively, Duke is allowing 31 points and 347 yards per game. Jaiden Francois leads the Duke Blue Devils with 13 tackles, Vincent Anthony Jr. has 3.5 sacks and Chandler Rivers has 2 pass deflections.
Tulane Green Wave Betting Preview
The Tulane Green Wave beat Northwestern and South Alabama, and they play Ole Miss next. Tulane Green Wave have won 10 of their last 13 games. Jake Retzlaff is completing 56.4 percent of his passes for 277 yards, 2 touchdowns and 0 interceptions. Omari Hayes and Bryce Bohanon have combined for 139 receiving yards on 15 catches, while Justyn Reid has 4 receptions.
The Tulane Green Wave ground game is averaging 255 yards per contest, and Jake Retzlaff leads the way with 177 yards and 2 touchdowns. Defensively, Tulane is allowing 17 points and 329 yards per game. Jack Tchienchou leads the Tulane Green Wave with 16 tackles, Santana Hopper has 1 sack and Javion White has 2 interceptions.
Duke Blue Devils @ Tulane Green Wave Betting Trends: Week 3
Why the Tulane Green Wave will win
- Tulane has won each of its last eight September games against non-AP-ranked teams.
- Duke has failed to cover the spread in four of its last five games against non-conference opponents.
- Tulane has covered the spread in each of its last three home games against non-conference opponents.
- Tulane has won the first half in each of its last nine games against non-conference opponents at Yulman Stadium.
- Tulane has won the first quarter in eight of its last nine games against non-conference opponents at Yulman Stadium.
Why the Duke Blue Devils will win
- Duke has won each of its last seven September games against non-AP-ranked teams.
- Duke has covered the spread in nine of its last 10 games as an underdog against non-AP-ranked teams.
- Tulane has failed to cover the spread in four of its last five games.
- Duke has won the first half in four of its last five games against opponents from the American Conference.
- Duke has won the first quarter in six of its last eight games against non-conference opponents.
Total Points Facts
- Ten of Tulane’s last 11 games against teams from North Carolina have gone UNDER the total points line.
- Each of Duke’s last four games against non-conference opponents have gone OVER the total points line.
Tulane Green Wave Player Prop Facts
- Heading into Week 3, Justyn Reid ranks T1st amongst qualified players for catch rate (100.0%) this season.
Duke Blue Devils Player Prop Facts
- Heading into Week 3, Vincent Anthony Jr. ranks T1st amongst FBS players for sacks (3.5) this season.
Matchup/League Facts
- Tulane ranks T1st among FBS teams for Q2 opponent points per game this season (0.0).
- Tulane ranks T1st among FBS teams for Q3 opponent points per game this season (0.0).
- Duke ranks 5th among FBS teams for passing yards per game this season (372.5).
- Duke ranks T128th among FBS teams for H2 opponent points per game this season (19.0).
Tulane vs Duke Prediction
Duke is a talented team capable of winning this game on the road, but I want nothing to do with this squad after what happened to Illinois. Duke outplayed Illinois for three quarters but couldn’t pull away due to constant mental mistakes and poor coaching. It led to Illinois blowing the doors off in the fourth quarter. It’s bad vibes with this squad and there could be a carry-over effect if they’re not careful.
Tulane has covered 11 of its last 15 games as a favorite. If Duke brings that undisciplined style of ball on the road, this game will get ugly. I’ll gladly lay the small number with Tulane at home.
