Tulane vs Ole Miss Prediction Football Picks Today 12/20/25

In this article, we will formulate a Tulane vs Ole Miss Prediction for this College Football Playoff First Round Game on Saturday, December 20^th. Let’s take a look at the prediction for this College Football matchup.

Ole Miss Rebels Preview

Ole Miss has an 11-1 record this season and finished 2nd in the SEC. They are coming off a 38-19 road win against Mississippi State. Offensively, Ole Miss averages 37.2 points per game, ranking 11th in the nation, while defensively, they allow 20.1 points per game, which is 25th. Ole Miss averages 498.1 total yards per game (309.6 passing and 188.5 rushing), while allowing 333.1 total yards per game (150.5 rushing and 182.6 passing).

Trinidad Chambliss leads Ole Miss with 3,016 passing yards with 65.5% completed passes and 18 touchdowns. Kewan Lacy leads the team in rushing yards with 1,279, while Harrison Wallace III has a team-high 46 receptions for 719 receiving yards. Defensively, T.J. Dudley has a team-high 77 total tackles (36 of them solo), while Princewill Umanmielen leads the team in sacks, with 6.5, and Wydett Williams, Jr. has a team-high 3 interceptions.

Tulane Green Wave Preview

Tulane has an 11-2 record this season and finished 2nd in the American. They are coming off a 34-21 home win against North Texas. Offensively, Tulane averages 29.1 points per game, ranking 58th in the nation, while defensively, they allow 22.6 points per game, which is 52nd. Tulane averages 410.7 total yards per game (240.5 passing and 170.2 rushing), while allowing 375.5 total yards per game (120.4 rushing and 255.2 passing).

Jake Retzlaff leads Tulane with 2,862 passing yards with 62.4% completed passes and 14 touchdowns. Javin Gordon leads the team in rushing yards with 505, while Anthony Brown has a team-high 35 receptions for 466 receiving yards. Defensively, Jack Tchienchou has a team-high 77 total tackles (50 of them solo), while Harvey Dyson III leads the team in sacks, with 7, and Jaheim Johnson has a team-high 4 interceptions.

Tulane vs Ole Miss Prediction

In this Tulane vs Ole Miss Prediction, Ole Miss is coming as -17.5-point favorites. Both teams have been excellent this season, as both have exactly 11 wins each, with Ole Miss having lost only once. Ole Miss has been undefeated at home and has been slightly better against the spread than Tulane this season and they are better both offensively and defensively, with a +17.1 point differential, while Tulane has a +6.5 point differential. Ole Miss is the rightful favorite in this matchup, but laying 17.5 points in a playoff game against a team that was 11-2 in the regular season is an exaggeration. I expect the guests to keep this one relatively close, so take Tulane and get the +17.5 points in this one.