UCLA vs USC Prediction Football Picks Today 11/29/25

In this article, we will formulate an UCLA vs USC Prediction for this College Football Week 14 game on Saturday, November 29^th. Let’s take a look at the prediction for this College Football matchup.

USC Trojans Preview

USC has an 8-3 record this season and is sitting 3rd in the Big Ten. They are coming off a 42-27 road loss against Oregon. Offensively, USC averages 37.2 points per game, ranking 14th in the nation, while defensively, they allow 23.5 points per game, which is 61st. USC averages 479.2 total yards per game (301 passing and 178.2 rushing), while allowing 352.5 total yards per game (148.8 rushing and 203.6 passing).

Jayden Maiava leads USC with 3,174 passing yards with 65.7% completed passes and 21 touchdowns. King Miller leads the team in rushing yards with 749, while Makai Lemon has a team-high 78 receptions for 1,124 receiving yards. Defensively, Desman Stephens II has a team-high 77 total tackles (48 of them solo), while Kameryn Crawford leads the team in sacks, with 3.5, and Bishop Fitzgerald leads the team with 5 interceptions.

UCLA Bruins Preview

UCLA has a 3-8 record this season and is sitting 12th in the Big Ten. They are coming off a 48-14 home loss against Washington. Offensively, UCLA averages 18.9 points per game, ranking 123rd in the nation, while defensively, they allow 33.8 points per game, which is 125th. UCLA averages 320.9 total yards per game (178.5 passing and 142.5 rushing), while allowing 386.9 total yards per game (195.8 rushing and 191.1 passing).

Nico Iamaleava leads UCLA with 1,728 passing yards with 63.5% completed passes and 12 touchdowns. Nico Iamaleava leads the team in rushing yards with 490, while Kwazi Gilmer has a team-high 40 receptions for 462 receiving yards. Defensively, JonJon Vaughns has a team-high 102 total tackles (43 of them solo), while Jacob Busic leads the team in sacks, with 1.0, and Scooter Jackson leads the team with 2 interceptions.

UCLA Bruins @ USC Trojans Betting Trends: Week 14

Why the USC Trojans will win

• USC has won each of its last 10 games against non-AP-ranked teams.
• UCLA has lost each of its last nine road games against AP-ranked teams.
• UCLA has failed to cover the spread in each of its last six games in November.
• The favorite has covered the spread in five of the last six games between UCLA and USC.
• UCLA has lost the first half in each of its last four games against conference opponents.

Why the UCLA Bruins will win

• The road team has won each of the last five games between UCLA and USC.
• The road team has covered the spread in each of the last five games between UCLA and USC.
• USC has failed to cover the spread in four of its last five games against non-AP-ranked teams.
• USC has lost the first half in three of its last four games against conference opponents.

Total Points Facts

• Each of UCLA’s last seven games against teams from California have gone UNDER the total points line.
• Six of USC’s last seven November games as a favorite have gone UNDER the total points line.

USC Trojans Player Prop Facts

• Heading into Week 14, Bishop Fitzgerald ranks T2nd amongst FBS players for interceptions (5) this season.

UCLA Bruins Player Prop Facts

• Heading into Week 14, Nico Iamaleava is one of only 51 players in the FBS to record 1,000 passing yards and 250 rushing yards this season.

Matchup/League Facts

• USC ranks 6th among FBS teams for 3rd down conversion percentage this season (51.1).
• USC ranks 7th among FBS teams for passing yards per game this season (301.0).
• UCLA ranks 133rd among FBS teams for Q1 points per game this season (1.8).
• UCLA ranks 4th among FBS teams for red zone percentage this season (96.4).

UCLA vs USC Prediction

In this UCLA vs USC Prediction, USC is coming as -21.5-point home favorites. USC has been the better team this season, as they have a superior overall record, they have been undefeated at home and are coming into this matchup in good from. On the flip side, UCLA has been struggling lately, having lost their last four games and have been terrible on the road, with a 1-4 record. They are also inferior than USC both offensively and defensively, with a -14.9 point differential, while USC has a +13.7 point differential and I expect them to win this one comfortably. Take USC and lay the -21.5 points at home.