College Football

Week 3: FSU vs Louisville 9/16/22 College Football Picks, Predictions, Odds

Florida State Seminoles (2-0) vs. Louisville Cardinals (1-1)
September 16, 2022 7:30 pm EDT
The Line: Louisville Cardinals +1.5 / Florida State Seminoles -1.5; Over/Under: 54.5
(Get latest betting odds)

The Louisville Cardinals and Florida State Seminoles do battle Friday in ACC week 3 college football action at Cardinal Stadium. The Florida State Seminoles look for their first 3-0 start since the 2015 season. The Louisville Cardinals look to get a game above a .500 record.

The Florida State Seminoles have lost 3 of their last 5 road games. Jordan Travis is completing 64.6 percent of his passes for 467 yards, 2 touchdowns and 0 interceptions. Johnny Wilson and Ontaria Wilson have combined for 213 receiving yards and 2 touchdowns, while Mycah Pittman has 7 receptions. The Florida State Seminoles ground game is averaging 269 yards per contest, and Treshaun Ward leads the way with 176 yards and 2 touchdowns. Defensively, Florida State is allowing 15 points and 256 yards per game. Tatum Bethune leads the Florida State Seminoles with 11 tackles, Jared Verse has 3 sacks and Jammie Robinson has 2 pass deflections.


The Louisville Cardinals have won 4 of their last 7 home games. Malik Cunningham is completing 58.8 percent of his passes for 353 yards, 0 touchdowns and 2 interceptions. Tyler Hudson and Ahmari Huggins-Bruce have combined for 268 receiving yards on 15 catches, while Marshon Ford has 5 receptions. The Louisville Cardinals ground game is averaging 181.5 yards per contest, and Tiyon Evans leads the way with 164 yards and 2 touchdowns. Defensively, Louisville is allowing 22.5 points and 394 yards per game. Kenderick Duncan leads the Louisville Cardinals with 17 tackles, Ashton Gillotte has 2 sacks and Jarvis Brownlee has 1 interception.

The Seminoles are 4-1 ATS in their last 5 road games and 4-1 ATS in their last 5 games overall. The Cardinals are 12-28-1 ATS vs. a team with a winning record and 1-4 ATS in their last 5 games on fieldturf. The under is 6-0 in Seminoles last 6 games overall. The over is 11-5 in Cardinals last 16 home games. The Seminoles are 1-5 ATS in their last 6 meetings. The home team is 5-2 ATS in their last 7 meetings.

The Louisville Cardinals will be up for this game after they just beat UCF, and this will be their first home game. Night contest, Louisville is sure to be juiced up. However, the Florida State Seminoles have had pretty much 2 weeks to prepare for this contest, and it’s fair to say they’re the more talented team in terms of depth and the type of athletes across the board. With extra time to prepare and Travis off to a solid start at quarterback, this is a game the Seminoles should win. We’re not being asked to lay anything crazy. Give me the Noles.

Randy Chambers's Free Pick: Florida State Seminoles -1.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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