West Virginia vs Houston Prediction 11/1/25 College Football Picks Today

In this article, we will formulate a West Virginia vs Houston Prediction for this College Football Week 10 game on Saturday, November 1^st. Let’s take a look at the prediction for this College Football matchup.

Houston Cougars Preview

Houston has a 7-1 record this season and is sitting 4th in the Big 12. They are 6-2 ATS, 5-3 in Over/Under and have a 3-1 home record and a 4-0 away record. Houston is coming off a 24-16 road win against Arizona State and will face UCF, Texas Christian and Baylor next.

Offensively, Houston averages 28.8 points per game, ranking 71st in the nation, while defensively, they allow 18.6 points per game, which is 22nd. Houston averages 381.3 total yards per game (210.0 passing and 171.3 rushing), while allowing 330.8 total yards per game (120.4 rushing and 210.4 passing).

Conner Weigman leads Houston with 1,581 passing yards with 63.7% completed passes and 12 touchdowns. Dean Connors leads the team in rushing yards with 586, while Tanner Koziol has a team-high 43 receptions for 450 receiving yards. Defensively, Jalen Garner has a team-high 53 total tackles (25 of them solo), while Eddie Walls III leads the team in sacks, with 5.5. Wrook Brown, Marc Stampley II, Latreveon McCutchin, Will James, Blake Thompson and C.J. Douglas lead the team with one interception each.

West Virginia Mountaineers Preview

West Virginia has a 2-6 record this season and is sitting 16th in the Big 12. They are 4-4 ATS, 3-5 in Over/Under and have a 2-2 home record and a 0-4 away record. West Virginia is coming off a 17-23 home loss against Texas Christian and will face Colorado, Arizona State and Texas Tech next.

Offensively, West Virginia averages 20.5 points per game, ranking 115th in the nation, while defensively, they allow 29.9 points per game, which is 107th. West Virginia averages 352.6 total yards per game (176.5 passing and 176.1 rushing), while allowing 407.3 total yards per game (160.1 rushing and 247.1 passing).

Nicco Marchiol leads West Virginia with 720 passing yards with 67.3% completed passes and 2 touchdowns. Jahiem White leads the team in rushing yards with 133, while Cam Vaughn has a team-high 27 receptions for 419 receiving yards. Defensively, Fred Perry has a team-high 50 total tackles (32 of them solo), while Chase Wilson leads the team in sacks, with 3.0. Darrian Lewis, Chase Wilson, Jason Chambers, Nick Taylor, Ben Cutter and Jordan Walker lead the team with one interception each.

West Virginia Mountaineers @ Houston Cougars Betting Trends: Week 10

Why the Houston Cougars will win

• West Virginia has lost each of its last 11 games against AP-ranked teams.
• Houston has won each of its last six games against non-AP-ranked teams.
• West Virginia has failed to cover the spread in 10 of its last 11 November games against AP-ranked teams.
• Houston has covered the spread in each of its last four games as a favorite in Texas.
• West Virginia has lost the first half in each of its last six games against conference opponents.

Why the West Virginia Mountaineers will win

• Houston has lost each of its last four November games against non-AP-ranked teams.
• The road team has won four of Houston’s last five games.
• Houston has failed to cover the spread in each of its last four November games as a favorite.
• The road team has covered the spread in three of Houston’s last four games.

Total Points Facts

• Each of Houston’s last five games against non-AP-ranked teams have gone OVER the total points line.
• Each of West Virginia’s last four road games against AP-ranked teams have gone OVER the total points line.

Houston Cougars Player Prop Facts

• Heading into Week 10, Dean Connors leads the Big 12 Conference for rush attempts (135) this season.

West Virginia Mountaineers Player Prop Facts

• Heading into Week 10, Cam Vaughn leads West Virginia for touchdowns (3) this season.

Matchup/League Facts

• Houston ranks 1st among FBS teams for Q3 opponent points per game this season (0.8).
• Houston is one of only seven FBS teams undefeated in road games this season (4-0).
• West Virginia ranks 134th among FBS teams for H1 points per game this season (6.4).
• West Virginia ranks 133rd among FBS teams for Q1 points per game this season (1.8).

West Virginia vs Houston Prediction

In their only previous meeting in 2023, Houston won 41-39 at home. In this West Virginia vs Houston Prediction, Houston is coming as -13.5-point road favorites, with the total set at 49.5 points. Both teams are coming into this matchup in opposite trajectories, as Houston has lost only once in their 8 games played this season and are 6-2 ATS, while on the flip side, West Virginia has five consecutive losses. Houston is superior both on offense and defense, winning by an average of 10.2 points per game, while West Virginia has a -9.4-point differential. I expect the hosts to dominate this game, so take Houston and lay the -13.5 points in this one.