Wyoming vs Northern Illinois Prediction Football Picks Today 10/17/26
Northern Illinois Huskies (0-5) vs. Wyoming Cowboys (3-3)
October 17, 2026 3:30 pm EDT
The Line: Wyoming Cowboys -305 / Northern Illinois Huskies 245; Over/Under: 41.5
(Get latest betting odds)
In this article we will formulate a Wyoming vs Northern Illinois prediction for this College Football game on Saturday, October 17th at War Memorial Stadium in Laramie, Wyoming. Let’s take a look at the prediction for this Week 7 matchup.
Wyoming Cowboys Betting Preview
The Wyoming Cowboys are 3-3 (2-1) this season after they defeated San Jose State in overtime by a score of 16-13 last week. Wyoming trailed 7-6 at halftime and 13-6 in the fourth, but they were able to tie the game and get the win in OT. The Cowboys out gained SJSU by a total of 345-326, went 3-15 on third downs, and lost the turnover battle by a total of 2-1 in the game. Tyler Hughes threw for 114 yards, one touchdown, and one interception, while Markell Holman caught four passes for 40 yards. Hughes also led the ground game with 27 carries for 92 yards in the win.
Prior to that game, Wyoming lost to North Dakota State by a score of 28-0, but did beat Hawaii by a score of 27-10 before that. The Cowboys have scored 14.5 points per game with 138.2 passing yards and 163.7 rushing yards per game, while they have allowed 20.5 points against per game this season. Tyler Hughes has thrown for 822 yards with three touchdowns and seven interceptions, while Samuel Harris has 65 carries for 324 yards and two scores this season.
Northern Illinois Huskies Betting Preview
The Northern Illinois Huskies are 0-5 (0-1) this year after they lost to Air Force by a score of 28-7 in their last game. Northern Illinois trailed 14-7 at halftime and they were shutout 14-0 in the second half in the loss. The Huskies were out gained by a total of 433-253, went 3-9 on third downs, and lost the turnover battle by a total of 1-0 in the game. Taron Dickens threw for 140 yards and one interception, while DeAree Rogers caught seven passes for 81 yards. Telly Johnson Jr rushed eight times for 47 yards and one score in the game.
Prior to that loss, Northern Illinois lost to Georgia State by a score of 35-14 and Arizona by a score of 42-17. The Huskies have scored 12.4 points per game with 204.8 passing yards and 86.0 rushing yards per game, while they have allowed 34.6 points against per game this season. Taron Dickens has thrown for 977 yards with three touchdowns and three interceptions this year.
Why the Wyoming Cowboys will win
- Northern Illinois has lost each of its last 13 games as an underdog.
- Wyoming has won each of its last six home games after coming off overtime.
- Northern Illinois has failed to cover the spread in 10 of its last 11 games as an underdog.
- The favorite has covered the spread in nine of Northern Illinois’ last 11 games.
- Wyoming has won the first quarter in three of its last four games after coming off overtime.
- Northern Illinois has lost the first half in each of its last 10 games as a road underdog.
Why the Northern Illinois Huskies will win
- Northern Illinois has won six of its last seven October games as a road underdog.
- Wyoming has failed to cover the spread in eight of its last 10 games.
- The underdog has covered the spread in four of Wyoming’s last five games.
- The road team has won the first quarter in three of Northern Illinois’ last four games.
- Wyoming has lost the first half in nine of its last 10 games.
Total Points Facts
- Each of Wyoming’s last nine games against conference opponents have gone UNDER the total points line.
- Four of Northern Illinois’ last five games against conference opponents have gone OVER the total points line.
Wyoming Cowboys Player Prop Facts
- Heading into Week 7, Markell Holman leads Wyoming for touchdowns (3) this season.
Northern Illinois Huskies Player Prop Facts
- DeAree Rogers has recorded 7+ receptions in four consecutive games – equal-longest streak in the FBS, heading into Week 7.
Matchup/League Facts
- Wyoming ranks 138th among FBS teams for H1 points per game this season (5.3).
- Wyoming ranks 136th among FBS teams for Q1 points per game this season (1.5).
- Northern Illinois ranks 138th among FBS teams for points per game this season (12.4).
- Northern Illinois ranks 138th among FBS teams for Q3 points per game this season (0.0).
Wyoming vs Northern Illinois Prediction
Northern Illinois comes into this matchup looking for their first win of the season, but they have lost by at least 21 points in three straight games. The Huskies have scored 17 points or fewer in four of their last five games and will face a tough Wyoming defense here. The Cowboys have alternated wins and losses over their last five games and got a nice road win last week. This should be a lower scoring game, but I will back Wyoming to cover at home.