NFL DFS FanDuel Main Slate Lineup, Daily Fantasy Football Picks for 12/26/21

It’s NFL Sunday and we have some great DFS FanDuel action for Week 16! Let’s check out our NFL DFS “Main Slate” FanDuel lineup that features 11 games and starts at 1:00pm (EST)!

I use these lineups for both 50/50’s & GPP’s lines. It’s more of a cash lineup but I like playing some of the GPP’s and we have had success with both.

Do not forget to check me out on my Twitter (@BrettCU05) as this is the best place for me to post any last-minute adjustments/updates to our lineups!

Here is our NFL FanDuel “Main Slate” Lineup for this afternoon:

Good Luck!