Draftkings NFL Showdown Picks: Chiefs vs. Bills 11/2/25
Kansas City Chiefs vs. Buffalo Bills
November 30, 2025 4:25 pm EDT
The NFL presents Draftkings football fans with a regular season matchup featuring the Kansas City Chiefs and the Buffalo Bills. Let’s take a look at this game from a DFS perspective.
Before we dive into the Kansas City Chiefs vs. Buffalo Bills game let’s review the rules for the Draftkings single game showdown contest.
Draftkings Single Game Showdown Contest Rules
You have $50,000 to utilize on five players from either team. However, one of those players will be designated as your team captain. The captain accumulates 1.5 times the standard fantasy points. Additionally, the captain is 1.5 times the standard cost of the flex position.
The remaining four players in your lineup will receive the standard fantasy points. Having stated that, it is highly important for you to identify the correct player for your captain position if you hope to win a large field DFS GPP (guaranteed prize pool) showdown contest.
If you have additional questions regarding the rules for the single game showdown contest, I recommend that you check out the Draftkings website for more details.
*I recommend that all readers review the starting lineups for both teams prior to setting your DFS lineup for this one game slate.
Here are my Draftkings picks for Sunday afternoon’s Chiefs vs. Bills matchup.
Draftkings NFL Showdown Picks
Captain-Patrick Mahomes, Quarterback, Kansas City Chiefs $11,000
Quarterback Patrick Mahomes has played exceptional football for the Kansas City Chiefs this season. With that said, how has the veteran quarterback performed from a data perspective? Let’s examine Mahomes relevant player data from the 2025 NFL regular season to better shed light on his overall contributions to his team.
In the eight games that quarterback Patrick Mahomes has played for the Kansas City Chiefs in the 2025 NFL regular season, Mahomes has amassed 2,099 passing yards, 17 passing touchdowns, 280 rushing yards and four rushing touchdowns.
Examining the data just presented more closely, in the the eight games that quarterback Patrick Mahomes has played for the Kansas City Chiefs in 2025, Mahomes is averaging 25.4 Draftkings points a contest.
Earlier this month, in the Jacksonville Jaguars 31-28 upset win over the Kansas City Chiefs, Kansas City quarterback Patrick Mahomes certainly played at a high level. In the Jaguars victory over the Chiefs, Mahomes tallied 318 passing yards, one passing touchdown, 60 rushing yards and one rushing touchdown.
What is the primary reason I like Patrick Mahomes at the captain position? From a DFS construction standpoint, Mahomes offers direct access to all Chiefs touchdowns and passing yardage, which is critical in Showdown formats where capturing every scoring event is paramount.
As I noted in the rules section above, selecting the correct player at the captain position for a Draftkings NFL Football showdown lineup is absolutely vital if you hope to win a large field GPP (guaranteed prize pool) DFS contest. Keep that in mind as you construct your lineups.
In my opinion, Patrick Mahomes is the most likely player to post the most Draftkings points in this NFL regular season game. For that specific reson, I am rolling with Kansas City Chiefs quarterback Patrick Mahomes at the captain position for this one game NFL DFS slate.
Flex Plays
Rashee Rice, Wide Receiver, Kansas City Chiefs $10,600
Two weeks ago, in the Kansas City Chiefs dominant 31-0 shutout victory over the Los Angeles Raiders, Kansas City quarterback Patrick Mahomes targeted Rashee Rice a whopping ten times. In those ten targets just noted, Rice amassed seven receptions, 42 receiving yards and two receiving touchdowns.
Flex plays I like to play well in Monday night’s NFL regular season contest (Draftkings price noted): Josh Allen, Quarterback (Buffalo Bills) $11,400: Keon Coleman, Wide Receiver (Buffalo Bills) $5,800: Brashard Smith, Running Back (Kansas City Chiefs) $4,200: Harrison Butker, Kicker (Kansas City Chiefs) $5,000.
