Draftkings MLB DFS Picks: Dodgers vs. Diamondbacks 9/25/25
Los Angeles Dodgers vs. Arizona Diamondbacks
September 25, 2025 3:40 pm EDT
Major League Baseball presents Draftkings baseball fans with a National League matchup featuring the Los Angeles Dodgers and the Arizona Diamondbacks. Let’s take a look at this MLB game from a DFS perspective.
Before we dive into the Los Angeles Dodgers vs. Arizona Diamondbacks game let’s review the rules for the Draftkings MLB single game showdown contest.
Draftkings Single Game Showdown Contest Rules
You have $50,000 to utilize on five players from either team. However, one of those players will be designated as your team captain. The captain accumulates 1.5 times the standard fantasy points. Additionally, the captain is 1.5 times the standard cost of the flex position.
The remaining four players in your lineup will receive the standard fantasy points. Having stated that, it is highly important for you to identify the correct player for your captain position if you hope to win a large field DFS GPP (guaranteed prize pool) showdown contest.
If you have additional questions regarding the rules for the single game showdown contest, I recommend that you check out the Draftkings website for more details.
*I recommend that all readers review the starting lineups for both teams prior to setting your DFS lineup for this one game slate.
Here are my Draftkings picks for this afternoon’s Dodgers vs. Diamondbacks matchup.
Draftkings MLB DFS Picks
Captain-Yoshinobu Yamamoto, Starting Pitcher, Los Angeles Dodgers $12,000
On Thursday afternoon, Major League Baseball presents the final game of a three-game National League series featuring the Los Angeles Dodgers and the Arizona Diamondbacks.
How are these two teams playing entering today’s MLB game? The Los Angeles Dodgers arrive at the third game of this three-game series with the Arizona Diamondbacks playing good baseball. The Dodgers have won five of the team’s last seven games played in the 2025 MLB regular season, including a 7-5 victory over the San Francisco Giants five days ago.
Similar to the Los Angeles Dodgers, the Arizona Diamondbacks are playing quality baseball entering the final game of this National League series. The Diamondbacks have won three of the team’s last four games played in the 2025 MLB regular season, including a 4-3 victory over the Philadelphia Phillies last week.
Now that we have identified how both of these teams are currently playing let’s shift our focus to today’s contest. Starting pitcher Yoshinobu Yamamoto has certainly been an important part of the Los Angeles Dodgers starting pitching rotation this season. With that said, how has Yamamoto performed from a statistical perspective in 2025? Let’s review the veteran pitcher’s relevant game data from the 2025 MLB regular season to answer that question.
Through 29 starts made in 2025, Los Angeles Dodgers starting pitcher Yoshinobu Yamamoto has compiled an 11-8 (win-loss record) and a 2.58 ERA (Earned Run Average) which ranks fifth in MLB. Additionally, Yamamoto has tallied a 0.99 WHIP (Walks and Hits per Innings Pitched), 194 strikeouts (14th in MLB) while allowing 57 walks in 167.2 innings pitched this season.
What did we learn from the data just presented? The data clearly illustrates that Yoshinobu Yamamoto can post a large number of DFS points on any given night. I fully expect that trend to continue in tonight’s matchup with the Arizona Diamondbacks.
In my view, Yoshinobu Yamamoto is the most likely player to post the most Draftkings points in this MLB regular season game. For that specific reason, I am backing Los Angeles Dodgers starting pitcher Yoshinobu Yamamoto at the captain position for this one game MLB DFS slate.
Flex plays I like to play well in this MLB regular season contest (Draftkings price noted): Nabil Crismatt, Starting Pitcher (Arizona Diamondbacks) $10,600: Shohei Ohtani, Outfielder (Los Angeles Dodgers) $10,000: Andy Pages, Outfielder (Los Angeles Dodgers) $7,400.
