Draftkings NFL Showdown Picks: Dolphins vs. Bills 9/18/25
Miami Dolphins vs. Buffalo Bills
September 17, 2025 8:15 pm EDT
The NFL presents Draftkings football fans with a regular season matchup featuring the Miami Dolphins and the Buffalo Bills. Let’s take a look at this game from a DFS perspective.
Before we dive into the Miami Dolphins vs. Buffalo Bills game let’s review the rules for the Draftkings single game showdown contest.
Draftkings Single Game Showdown Contest Rules
You have $50,000 to utilize on five players from either team. However, one of those players will be designated as your team captain. The captain accumulates 1.5 times the standard fantasy points. Additionally, the captain is 1.5 times the standard cost of the flex position.
The remaining four players in your lineup will receive the standard fantasy points. Having stated that, it is highly important for you to identify the correct player for your captain position if you hope to win a large field DFS GPP (guaranteed prize pool) showdown contest.
If you have additional questions regarding the rules for the single game showdown contest, I recommend that you check out the Draftkings website for more details.
*I recommend that all readers review the starting lineups for both teams prior to setting your DFS lineup for this one game slate.
Here are my Draftkings picks for tonight’s Dolphins vs. Bills matchup.
Draftkings NFL Showdown Picks
Captain-Josh Allen, Quarterback, Buffalo Bills $12,400
Veteran quarterback Josh Allen was certainly a standout performer for the Buffalo Bills in 2024. With that said, how did Allen perform from a statistical standpoint last season? Let’s review Josh Allen’s relevant key player game data from the 2024 NFL season to answer that question.
In the 17 games that quarterback Josh Allen played for the Buffalo Bills in the 2024 NFL regular season, Allen amassed a rather impressive 3,731 passing yards, 28 passing touchdowns, 531 rushing yards and 12 rushing touchdowns.
Looking closer at the data just presented, in the 17 games that quarterback Josh Allen played for the Buffalo Bills last season, Allen averaged 23.1 Draftkings points a game.
Shifting our focus to 2025, how is Josh Allen playing this season? Through two games played in the 2025 NFL regular season, Allen has accumulated 542 passing yards, two passing touchdowns, 89 rushing yards and two rushing touchdowns.
Two weeks ago, in the Buffalo Bills 41-40 victory over the Baltimore Ravens, Buffalo quarterback Josh Allen played exceptionally well. More specifically, Allen compiled 394 passing yards, two passing touchdowns, 31 rushing yards and two rushing touchdowns. What did we learn? The data clearly illustrates that Josh Allen can post a high number of DFS points on any give night.
As I noted in the rules section above, selecting the correct player at the captain position for a Draftkings NFL Football showdown lineup is absolutely vital if you hope to win a large field GPP (guaranteed prize pool) DFS contest. Keep that in mind as you construct your lineups.
In my view, Josh Allen is the most likely player to post the most Draftkings points in this NFL regular season game. For that specific reason, I am backing Buffalo Bills quarterback Josh Allen at the captain position for this one game NFL DFS slate.
Flex Plays
James Cook, Running Back, Buffalo Bills $10,600
In addition to Josh Allen, running back James Cook has been a key contributor for the Buffalo Bills this season.
In two games played in the 2025 NFL regular season, James Cook has tallied 176 rushing yards, three rushing touchdowns, six receptions and 61 receiving yards.
Flex plays I like to play well in this NFL regular season contest (Draftkings price noted): De’Von Achane, Running Back (Miami Dolphins) $10,800: Keon Coleman, Wide Receiver (Buffalo Bills) $6,800: Matt Prater, Kicker (Buffalo Bills) $5,000.
