FanDuel Best MLB DFS Picks: Astros vs. Athletics 9/24/25
Houston Astros vs. Athletics
September 24, 2025 10:05 pm EDT
Major League Baseball presents FanDuel baseball fans with an American League matchup featuring the Houston Astros and the Athletics. Let’s take a look at this MLB game from a DFS perspective.
Before we dive into the Houston Astros vs. Athletics game let’s review the rules for the FanDuel single game showdown contest.
FanDuel Single Game Contest Rules
Here are the FanDuel single game contest rules. You have $60,000 to utilize on five players from either team. However, one of those players will be designated as your team MVP. The MVP accumulates 1.5x times the standard FanDuel fantasy points value. Additionally, the MVP is 1.5 times the standard cost of the flex position.
The remaining five players in your lineup will be flex plays. The five flex positions will receive the standard FanDuel points value. Having stated that, it is highly important for you to identify the correct player for your MVP position if you hope to win a large field GPP (guaranteed prize pool) FanDuel single game contest.
If you have additional questions regarding the rules for the single game contest, I highly recommend that you check out the FanDuel website for more details.
*It should be noted that FanDuel does not utilize the pitcher position in single game MLB contests. Having stated that, only batters are available for single game MLB lineups on the FanDuel platform.
Here are my FanDuel picks for tonight’s Astros vs. Athletics matchup.
FanDuel MLB DFS Picks
MVP-Jose Altuve, Second Baseman, Houston Astros $9,400
On Tuesday night, Major League Baseball presents the opening game of a three-game American League series featuring the Houston Astros and the Athletics.
How are these two teams playing entering today’s MLB game? The Athletics arrive at the first game of this three-game series with the Houston Astros playing average baseball. The Athletics have won three of the team’s last six games played in the 2025 MLB regular season, including a 4-3 win over the Pittsburgh Pirates last week.
In direct contrast to the Athletics, the Houston Astros arrive at tonight’s American League game playing subpar baseball. More specifically, the Astros have lost four of the team’s last six games played this season, including a 6-4 loss to the Seattle Mariners four days ago.
Now that we have determined how both of these teams are currently playing let’s shift our attention to tonight’s contest. Talented second baseman Jose Altuve has been a standout performer for the Houston Astros in 2025. With that said, how has Altuve performed from a statistical standpoint? Let’s review the veteran second baseman’s relevant game data from the 2025 MLB regular season to answer that question.
In the 151 games that Jose Altuve has played for the Houston Astros in the 2025 MLB regular season, Altuve has compiled a .263 batting average, 26 home runs, 52 walks, 75 RBIs (runs batted in), ten stolen bases, 78 runs scored, a .325 OBP (On-Base Percentage) and a .766 OPS (On-Base Plus Slugging).
As I noted in the rules section above, selecting the correct player at the MVP position for a FanDuel MLB showdown lineup is absolutely vital if you hope to win a large field GPP (guaranteed prize pool) DFS contest. Keep that in mind as you construct your lineups.
In my opinion, Jose Altuve’s reasonable FanDuel price of $9,400 presents the best fantasy value on this slate. Having stated that, I am rolling with Houston Astros second baseman Jose Altuve at the MVP position for this one game MLB DFS slate.
Flex plays I like in this MLB regular season game (FanDuel price noted): Nick Kurtz, First Baseman (Athletics) $13,600: Lawrence Butler, Outfielder (Athletics) $8,400.



