FanDuel Best MLB DFS Picks: Giants vs. Dodgers 9/19/25

Major League Baseball presents FanDuel baseball fans with a National League matchup featuring the San Francisco Giants and the Los Angeles Dodgers. Let’s take a look at this MLB game from a DFS perspective.

Before we dive into the San Francisco Giants vs. Los Angeles Dodgers let’s review the rules for the FanDuel single game showdown contest.

FanDuel Single Game Contest Rules

Here are the FanDuel single game contest rules. You have $60,000 to utilize on five players from either team. However, one of those players will be designated as your team MVP. The MVP accumulates 1.5x times the standard FanDuel fantasy points value. Additionally, the MVP is 1.5 times the standard cost of the flex position.

The remaining five players in your lineup will be flex plays. The five flex positions will receive the standard FanDuel points value. Having stated that, it is highly important for you to identify the correct player for your MVP position if you hope to win a large field GPP (guaranteed prize pool) FanDuel single game contest.

If you have additional questions regarding the rules for the single game contest, I highly recommend that you check out the FanDuel website for more details.

*It should be noted that FanDuel does not utilize the pitcher position in single game MLB contests. Having stated that, only batters are available for single game MLB lineups on the FanDuel platform.

Here are my FanDuel picks for tonight’s Giants vs. Dodgers matchup.

FanDuel MLB DFS Picks

MVP-Shohei Ohtani, Outfielder, Los Angeles Dodgers $15,000

On Friday night, Major League Baseball presents the second game of a four-game National League series featuring the San Francisco Giants and the Los Angeles Dodgers.

How are these two teams playing entering today’s MLB game? The Los Angeles Dodgers arrive at the second game of this four-game series with the San Francisco Giants playing good baseball. The Dodgers have won eight of the team’s last 11 games played in the 2025 MLB regular season, including a dominant 10-2 win over the San Francisco Giants five days ago.

Conversely, the San Francisco Giants are playing below average baseball entering the second game of this National League series. The Giants have lost five of the team’s last six games played in the 2025 MLB regular season, including a 13-7 loss to the Los Angeles Dodgers last week.

Now that we have determined how both of these teams are currently playing let’s shift our focus to this evening’s contest. Talented outfielder Shohei Ohtani has certainly been an essential part of the Los Angeles Dodgers starting lineup in 2025. With that said, how has Ohtani performed from a statistical standpoint? Let’s examine the veteran outfielder’s relevant game data from the 2025 MLB regular season to answer that question.

In the 150 games that Shohei Ohtani has played for the Los Angeles Dodgers in the 2025 MLB regular season, Ohtani has compiled a rather impressive .283 batting average, 51 home runs (third in MLB), .93 RBIs (runs batted in), 138 runs scored (first in MLB), a .395 OBP (On-Base Percentage) and a 1.011 OPS (On-Base Plus Slugging) which ranks second in MLB.

In my view, Shohei Ohtani is the most likely player to amass the most FanDuel points in this MLB game. Having stated that, I am backing Los Angeles Dodgers outfielder Shohei Ohtani at the MVP position for this one game MLB DFS slate.

Flex plays I like in this evening’s MLB regular season game (FanDuel price noted): Freddie Freeman, First Baseman (Los Angeles Dodgers) $11,800: Andy Pages, Outfielder (Los Angeles Dodgers) $7,400: Heliot Ramos, Outfielder (San Francisco Giants) $6,600.