
FanDuel Best MLB Picks: White Sox vs. Blue Jays 6/21/25
Chicago White Sox vs. Toronto Blue Jays
June 21, 2025 3:07 pm EDT
Major League Baseball presents FanDuel baseball fans with an American League matchup featuring the Chicago White Sox and the Toronto Blue Jays. Let’s take a look at this MLB game from a DFS perspective.
Before we dive into the Chicago White Sox vs. Toronto Blue Jays game let’s review the rules for the FanDuel single game showdown contest.
FanDuel Single Game Contest Rules
Here are the FanDuel single game contest rules. You have $60,000 to utilize on five players from either team. However, one of those players will be designated as your team MVP. The MVP accumulates 1.5x times the standard FanDuel fantasy points value. Additionally, the MVP is 1.5 times the standard cost of the flex position.
The remaining five players in your lineup will be flex plays. The five flex positions will receive the standard FanDuel points value. Having stated that, it is highly important for you to identify the correct player for your MVP position if you hope to win a large field GPP (guaranteed prize pool) FanDuel single game contest.
If you have additional questions regarding the rules for the single game contest, I highly recommend that you check out the FanDuel website for more details.
*It should be noted that FanDuel does not utilize the pitcher position in single game MLB contests. Having stated that, only batters are available for single game MLB lineups on the FanDuel platform.
Here are my FanDuel picks for this afternoon’s White Sox vs. Blue Jays matchup.
FanDuel MLB DFS Picks
MVP-Vladimir Guerrero Jr., First Baseman, Toronto Blue Jays $12,800
On Saturday afternoon, Major League Baseball presents the second game of a three-game American League series featuring the Chicago White Sox and the Toronto Blue Jays.
How are these two teams playing entering today’s MLB game? The Toronto Blue Jays arrive at the second game of this three-game series with the Chicago White Sox playing subpar baseball. The Blue Jays have lost five of the team’s last seven games played in the 2025 MLB regular season, including a 9-5 loss to the Arizona Diamondbacks two days ago.
Similar to the Toronto Blue Jays, the Chicago White Sox are playing below average baseball entering today’s American League game. More specifically, the White Sox have lost eight of the team’s last nine games played this season, including a 10-2 loss to the Houston Astros last week.
Now that we have identified how both of these teams are currently playing let’s shift our focus to this afternoon’s contest. Talented first baseman Vladimir Guerrero Jr. has been a standout performer for the Toronto Blue Jays in 2025. Having stated that, how has Guerrero Jr. performed from a statistical perspective? Let’s review Guerrero Jr.’s relevant game data from the 2025 MLB regular season to answer that question.
In the 73 games that Vladimir Guerrero Jr. has played for the Toronto Blue Jays in the 2025 MLB regular season, Guerreo Jr. has compiled a .286 batting average, nine home runs, 43 walks, 38 RBIs (runs batted in), 43 runs scored, a .391 OBP (On-Base Percentage) and a .832 OPS (On-Base Plus Slugging).
Four days ago, in the Toronto Blue Jays 5-4 victory over the Arizona Diamondbacks, Blue Jays first baseman Vladimir Guerreo Jr. played rather well. In the Blue Jays win over Arizona, Guerrero Jr. tallied three hits (one home run, one double), one run scored and three RBIs. It should also be noted that in Toronto’s defeat of the Diamondbacks, Guerreo Jr. tallied a massive 34.7 FanDuel points.
In my opinion, Vladimir Guerreo Jr. is the most likely player to amass the most FanDuel points in this MLB game. For that specific reason, I am backing Toronto Blue Jays outfielder Vladimir Guerreo Jr. at the MVP position for this one game MLB DFS slate.
Flex plays I like in this game (FanDuel price noted): George Springer, Outfielder (Toronto Blue Jays) $10,800: Andrew Benintendi, Outfielder (Chicago White Sox) $7,400: Bo Bichette, Shortstop (Toronto Blue Jays) $12,200.