MLB DFS FanDuel Main Slate Lineup, Daily Fantasy Baseball Picks for 9/21/22

We have some great MLB action today as we have a 9-game MLB slate that starts at 7:05pm (EST)! Let’s check out who we have going for our MLB “Main Slate” FanDuel lineup!

This is a cash lineup that I make to enter 50/50 contests, however, I do still play these lineups in the big GPP’s just in case it really goes off for a huge day.

Do not forget to check me out on my Twitter (@BrettCU05) as this is the best place for me to post any last-minute adjustments/updates to our lineups!

Here is our MLB FanDuel “Main Slate” Lineup for today:

Good Luck!