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Cleveland Indians vs Chicago White Sox MLB Picks, Odds, Predictions 9/26/21

Chicago White Sox (87-68) vs. Cleveland Indians (76-78)
September 26, 2021 1:10 pm EDT
The Line: Cleveland Indians +150 / Chicago White Sox -208; Over/Under: -8.5
(Get latest betting odds)

The Chicago White Sox and Cleveland Indians meet Sunday in MLB action at Progressive Field. The White Sox need a win after losing five of their last eight games. The Indians look for a win after splitting their last 10 games.

The Chicago White Sox have scored four runs in their last three games and three or less runs in five of their last six games. The White Sox have lost seven of their last eight games when scoring three or less runs. Tim Anderson leads the White Sox with 152 hits and 58 RBI while Jose Abreu and Yoan Moncada have combined for 272 hits and 170 RBI. Lucas Giolito gets the ball, and he is 10-9 with a 3.70 ERA and 192 strikeouts this season. Giolito is 2-3 with a 2.21 ERA and 65 strikeouts in his career against the Indians.

The Cleveland Indians have scored 11 runs in their last three games and four or more runs in five of their last nine games. The Indians have won eight straight games when scoring four or more runs. Amed Rosario leads the Indians with 147 hits and 51 RBI while Jose Ramirez and Franmil Reyes have combined for 242 hits and 180 RBI. Triston McKenzie gets the ball, and he is 5-7 with a 4.67 ERA and 131 strikeouts this season. McKenzie is 0-1 with a 9.87 ERA and 27 strikeouts in his career against the White Sox.

The White Sox are 8-3 in their last 11 Sunday games. The Indians are 6-1 in their last 7 Sunday games and 2-7 in their last 9 home games. The under is 8-3-1 in White Sox last 12 road games. The over is 5-2 in Indians last 7 overall. The White Sox are 11-23 in the last 34 meetings in Cleveland.

The Chicago White Sox should win and Giolito has been consistently good this season. However, it feels like the White Sox are on cruise control entering the postseason and they’ve lost five of their last eight games. McKenzie has also been good lately, allowing just 16 earned runs in his last 50.1 innings. I’ll take a shot with the Indians and big plus money.

Randy Chambers's Free Pick: Cleveland Indians +150

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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