White Sox vs. Astros Pick – MLB Predictions & Odds 5/13/23

Chris RuffoloMay 13, 2023
White Sox vs. Astros Pick – MLB Predictions & Odds 5/13/23 player photo
Credit: USA Today Sports

The Houston Astros and the Chicago White Sox meet in MLB action from Guaranteed Rate Field on Saturday. Let’s dive into the odds, starting pitching matchup, history and make a prediction for this game.


Chicago is listed as a -125 home favorite while Houston is a +105 road underdog. The total for this game is set at 9 runs.

Starting Pitching Matchup

Brandon Bielak will start for the Astros here and is 0-1 with a 4.15 ERA and 6 strikeouts this season. Chicago is sending Dylan Cease to the mound here and is 2-2 with a 5.58 ERA and 49 strikeouts this season.

Matchup History

Houston’s 5-1 win on Friday made it five wins in the last seven head-to-head meetings between these two teams for the Astros over the White Sox.


Houston is 29-11 in their last 40 road games and 0-4 in their last 4 games against a team with a winning percentage below .400 while the over is 5-1 in their last 6 Saturday games. Chicago is 8-18 in their last 26 home games and 6-20 in their last 26 games overall while the over is 5-1-2 in their last 8 Saturday games.


I’m backing the Astros here. I’m not the biggest Brandon Bielak fan, but Dylan Cease hasn’t looked very good as of late, and I’m not trying to back him or the White Sox in the favorite role. Even if he turns it around here, he has to likely turn it over once he leaves to one of the worst bullpens in the majors this season. I think Houston can take advantage of that bullpen’s shortcomings here and get a win on the road in this one.

Chris Ruffolo's Free Pick:Houston +105
Chris Ruffolo photograph

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg