Angels vs Blue Jays Prediction 5/6/25 MLB Picks Today

The Toronto Blue Jays and the Los Angeles Angels meet Tuesday in MLB action from Angel Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Angels vs Blue Jays Prediction.

Starting Pitching Matchup

The Toronto Blue Jays did not have a starting pitcher announced at the time that this article was posted. Tyler Anderson will get the start for the Angels here, and Anderson is 2-0 with a 2.67 ERA and 27 strikeouts this season. In his last five starts against the Blue Jays, Anderson is 0-3 with a 5.53 ERA and 23 strikeouts.

Toronto Blue Jays Recap

The Toronto Blue Jays will be out to bounce back after ending up with a 5-4 loss in Sunday’s series finale against the Cleveland Guardians last time out to fall to 16-18 on the year. After this series, the Blue Jays will head on the road for a series against the Seattle Mariners.

Blue Jays Drop Back-To-Back Games

George Springer has 29 hits and Bo Bichette has 42 hits, with Springer adding 3 home runs, a triple, 8 doubles, and 13 RBIs while Bichette has 11 doubles and 14 RBIs. Andres Gimenez has added 23 hits with 4 doubles and 3 home runs and 10 RBIs this season, along with 9 stolen bases, while Anthony Santander has a team-high 33 strikeouts so far this season. Vladimir Guerrero Jr. also has 4 homers, 6 doubles, and 18 RBIs, while Springer also has a .309 batting average up to this point in the year.

Why the Toronto Blue Jays will win

• The Blue Jays have won each of their last seven games against the Angels.
• The Angels have lost 12 of their last 13 games against American League opponents.
• The Angels have failed to cover the run line each of their last eight home games against AL East opponents that held a losing record.
• The Blue Jays have covered the run line in seven of their last eight games at Angel Stadium of Anaheim.

Toronto Blue Jays Player Prop Facts

• Anthony Santander has recorded at least one Double in three of his last four appearances against the Angels after not playing the previous day.
• Anthony Santander has hit a home run in each of his last three appearances against the Angels after not playing the previous day.
• Anthony Santander has recorded three or more RBIs in each of his last four appearances against the Angels after not playing the previous day.
• Vladimir Guerrero Jr. has scored at least one run in each of the Blue Jays’ last six games at Angel Stadium of Anaheim.
• Daulton Varsho has recorded at least one hit in each of his last nine appearances against opponents that held a losing record.
• Bo Bichette has recorded at least one Single in each of his last nine appearances in night games against AL teams that held a losing record.
• George Springer ranks 5th amongst qualified players for On Base Percentage (.416) this season.

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to shake off their 13-1 loss at the hands of the Detroit Tigers in Sunday’s series finale to slip to 13-20 on the year. After this series, the Angels will welcome the Baltimore Orioles to town.

Angels Drop 8 Of Their Last 9

Logan O’Hoppe has 27 hits, including 9 home runs and 15 RBIs, while Nolan Schanuel has 27 hits with 5 doubles, a triple, 2 home runs, and 9 RBIs. Luis Rengifo has 5 doubles with his 25 hits, and Taylor Ward also has 22 hits as well, while Mike Trout’s added 9 home runs and 18 RBIs so far this season. Jorge Soler also has 7 doubles, 6 home runs, and 13 RBIs, but also has the unfortunate distinction of leading the Angels with 39 strikeouts so far this season. Kyren Paris has also chipped in 18 hits with a triple, 5 home runs, and 10 RBIs in addition to 5 stolen bases.

Why the Los Angeles Angels will win

• The Blue Jays have lost each of their last five games against AL West opponents.
• The home team has won each of the last four games between the Blue Jays and Angels.
• The Blue Jays have failed to cover the run line each of their last five night games against American League opponents that held a losing record.
• The Angels have covered the run line in four of their last five night games against American League opponents following a home loss.

Los Angeles Angels Player Prop Facts

• Tyler Anderson has recorded six or more strikeouts in each of his last four appearances in night games against AL teams that held a losing record.
• Mike Trout has recorded at least one RBI in each of his last four appearances against the Blue Jays.
• Travis d’Arnaud has recorded a Double in four of his last five appearances.
• Logan O’Hoppe has hit a home run in four of his last five home appearances against opponents that held a losing record.
• Tim Anderson has recorded at least one Single in nine of his last 10 appearances at Angel Stadium of Anaheim against opponents that held a losing record.
• Logan O’Hoppe has scored at least one run in each of his last six home appearances against opponents that held a losing record.
• Yoan Moncada has recorded at least one hit in each of his last 14 home appearances against opponents that held a losing record.

Total Runs Facts

• Each of the Blue Jays’ last five road games against AL West opponents have gone UNDER the total runs line.
• Five of the Angels’ last six games have gone OVER the total runs line.

Angels vs Blue Jays Prediction

I’m going to side with the Blue Jays here. I get the case to be made for the Angels as Los Angeles is at home here, but the problem for the Halos is that their offense has fallen off a cliff in recent games. It’s just really hard to trust this team to do their job right now. The Blue Jays have had success against Anderson in the past, and I think that Toronto gets back on track with a strong showing in Tuesday’s opener. Give me Toronto here.