Angels vs Cardinals Prediction 7/22/26 MLB Picks Today

The St. Louis Cardinals and Los Angeles Angels meet Wednesday in MLB action at Angel Stadium. Here’s an Angels vs Cardinals Prediction. This article will include an Angels vs Cardinals Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 51-49 on the year and play the Diamondbacks and Reds next. The St. Louis Cardinals are batting .241 on the season, with a .318 OBP and a .385 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.16 ERA and a 1.33 WHIP. Jordan Walker leads the St. Louis Cardinals with 110 hits and 76 RBI, while Alec Burleson and JJ Wetherholt have combined for 203 hits and 108 RBI.

Hunter Dobbins gets the ball for the St. Louis Cardinals, and he is 1-1 with a 4.03 ERA and 23 strikeouts this season. This will be Dobbins’ second career game against the Los Angeles Angels.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 41-61 on the year and play the Astros and Giants next. The Los Angeles Angels are batting .240 on the season, have a .315 OBP, and have a .389 slugging percentage. The Los Angeles Angels’ pitching staff has a 4.56 ERA and a 1.37 WHIP. Jo Adell leads the Los Angeles Angels with 95 hits and 57 RBI, while Zach Neto and Nolan Schanuel have combined for 179 hits and 81 RBI.

Reid Detmers gets the ball for the Los Angeles Angels, and he is 3-6 with a 4.16 ERA and 130 strikeouts this season. Detmers is 0-0 with a 5.14 ERA and 11 strikeouts in his career against the St. Louis Cardinals.

Why the Los Angeles Angels will win

• The Cardinals have lost each of their last five games after playing the previous day.
• The Angels have won seven of their last eight games against the Cardinals following a win.
• The Cardinals have failed to cover the run line in each of their last five games against American League opponents after playing the previous day.
• The Angels have covered the run line in seven of their last eight games against the Cardinals following a win.
• The Angels have won the first inning in three of their last four day games against NL Central opponents that held a winning record.
• The Angels have led after 3 innings in eight of their last nine games as favorites against National League opponents.
• The Angels have led after 5 innings in eight of their last nine games as favorites against National League opponents.

Why the St. Louis Cardinals will win

• The Angels have lost each of their last seven day games against National League opponents following a win.
• The Cardinals have won each of their last seven Wednesday day games as underdogs against American League opponents.
• The Angels have failed to cover the run line in each of their last seven day games against National League opponents following a win.
• The Cardinals have covered the run line in seven of their last eight games as underdogs following a loss.
• The Angels have trailed after 3 innings in each of their last seven Wednesday games against National League opponents that held a winning record.
• The Angels have trailed after 5 innings in each of their last eight day games at Angel Stadium of Anaheim against National League opponents.

Total Runs Facts

• Each of the Angels’ last eight games have gone UNDER the total runs line.
• Each of the Cardinals’ last four road games against AL West opponents have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in nine of Hunter Dobbins’ last 10 appearances as a starter.
• There has been at least one run scored in the first inning in six of the Angels’ last seven home games.

Los Angeles Angels Player Prop Facts

• Jo Adell has hit at least one home run in each of the Angels’ last three games against opponents that held a winning record.
• Reid Detmers has recorded seven or more strikeouts in six of his last seven home appearances.
• Zach Neto has recorded at least one hit in each of his eight previous appearances against the Cardinals.
• Mike Trout ranks 9th amongst qualified players for On Base Percentage (.387) this season.

St. Louis Cardinals Player Prop Facts

• JJ Wetherholt has hit at least one home run in four of his last five appearances in day games against AL teams that held a losing record.
• Jordan Walker has recorded at least one hit in each of the Cardinals’ last 12 games.
• Jordan Walker ranks T7th in the league in Hits (110) this season.

Matchup/League Facts

• The Angels rank 30th in the league for strikeouts against this season (967).
• The Angels rank 30th in the league for strikeouts against this season (967).
• The Cardinals rank 28th in the league for doubles this season (133).
• The Cardinals rank 28th in the league for doubles this season (133).

Angels vs Cardinals Prediction

As I said yesterday, the Angels are a team I’ve made a killing over the years blindly fading. This is an awful organization. However, the Angels have won 3 straight games and the Cardinals are in a free fall. Dobbins also has just 22.1 innings this season, so the sample size isn’t trustworthy. Detmers is coming off a strong showing against the Tigers and has been good overall these last two months. Detmers has a top-20 WHIP at 1.12 on the season. We hit on the Angels yesterday, and I’m going back to the well. I don’t back the Angels often.