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Angels vs Cubs Prediction 4/1/26 MLB Picks Today

LA Angels (3-3) vs. Chicago Cubs (2-3)
April 1, 2026 2:20 pm EDT
The Line: Chicago Cubs -171 / LA Angels 141; Over/Under: 6.5
(Get latest betting odds)

In this article, we will formulate an Angels vs Cubs Prediction for this MLB matchup on Wednesday, April 1st in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview

The Chicago Cubs have a 2-3 record this season and are sitting in the last place of the NL Central. They have a 2-3 home record and are coming off a 2-0 home loss to the Angels. Their previous three games were a 7-2 home win over the Angels, a 6-3 home loss, and a 10-2 home win over the Nationals.

The Cubs have a .213 batting average this season, .316 OBP and .350 Slugging percentage. Chicago’s pitching staff has a 4.00 ERA and 1.18 WHIP. Pete Crow-Armstrong is the team’s best hitter with a .263 batting average. Ian Happ leads the team in RBI with 5, also adding a team-high three home runs.

Matthew Boyd (L) is the projected starting pitcher for the Cubs, and he has a 0-1 record, 14.73 ERA and 1.91 WHIP.

Los Angeles Angels Preview

The Los Angeles Angels have a 3-3 record this season and are sitting in the third place of the AL West. They have a 3-3 road record and are coming off a 2-0 road win over the Cubs. Their previous three games were a 7-2 road loss to the Cubs, a 9-7 road loss, and an 11-9 road loss to the Astros.

The Angels have a .217 batting average this season, .346 OBP and .399 Slugging percentage. Los Angeles’ pitching staff has a 3.53 ERA and 1.53 WHIP. Oswald Peraza is the team’s best hitter with a .353 batting average. Jorge Soler leads the team in RBI with 5, and Mike Trout adds a team-high two home runs.

Yusei Kikuchi (L) is the projected starting pitcher for the Angels, and he has a 0-0 record, 4.15 ERA and 2.08 WHIP.

Los Angeles Angels @ the Chicago Cubs Betting Trends: April 1, 2026

 

  • Probable Starting Pitcher: Matthew Boyd      Record this season: 0-1      ERA: 14.73
  • Home Record: 0-1
  • Last 5 against Angels: 2-1

Why the Chicago Cubs will win

  • The Cubs have won each of their last six games following a home loss.
  • The Angels have lost seven of their last eight games against NL Central opponents.
  • The Angels have failed to cover the run line each of their last five games against NL Central opponents that held a losing record.
  • The Cubs have covered the run line in each of their last five games following a home loss.
  • The Angels have trailed after 3 innings in each of their last five games against NL Central opponents that held a losing record.
  • The Cubs have won the first inning in three of their last four games as home favorites against AL West opponents.
  • The Angels have trailed after 5 innings in each of their last four day games against National League opponents that held a losing record.

 

  • Probable Starting Pitcher: Yusei Kikuchi      Record this season: 0-0      ERA: 4.15
  • Road Record: 0-0
  • Last 5 against Cubs: –

Why the Los Angeles Angels will win

  • The underdogs have won four of the Cubs’ last six games at Wrigley Field.
  • The Cubs have lost four of their last five Wednesday games as favorites against American League opponents.
  • The Cubs have failed to cover the run line in each of their last eight Wednesday games as home favorites against American League opponents.
  • The Angels have covered the run line in nine of their last 10 Wednesday games against NL Central opponents that held a losing record.
  • The Cubs have lost the first inning in three of their last four day games against American League opponents.

Total Runs Facts

  • Each of the Cubs’ last seven games after playing the previous day have gone UNDER the total runs line.
  • Seven of the Angels’ last eight games as underdogs against the Cubs have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Cubs’ last six home games against AL West opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Angels’ last five day games against NL Central opponents.

Chicago Cubs Player Prop Facts

  • Ian Happ has hit a home run in three of the Cubs’ last four games.
  • Matthew Boyd has recorded a win in three of his last four home appearances against AL opponents.
  • Seiya Suzuki has recorded at least one hit in each of his last 14 home appearances.
  • Nico Hoerner ranks T1st in the league in Steals (3) this season.

Los Angeles Angels Player Prop Facts

  • Zach Neto has hit a home run in three of his last four appearances in day games against teams that held a losing record.
  • Yusei Kikuchi has recorded five or more strikeouts in 12 of his last 13 appearances in day games.
  • Anthony Rendon has recorded at least one hit in 20 of his last 21 road appearances against NL Central opponents that held a losing record.
  • Mike Trout ranks T5th in the league in Steals (2) this season.

Matchup/League Facts

  • The Cubs rank T3rd in the league for steals this season (6).
  • The Cubs rank T27th in the league for doubles this season (4).
  • The Angels rank 1st in the league for home runs this season (10).
  • The Angels rank 1st in the league for walks this season (36).

Angels vs Cubs Prediction

The Cubs are 5-1 in their last 6 meetings against the Angels and the under is 9-1 in their last 10 meetings.

In this Angels vs Cubs Prediction, the Cubs are coming as -165 home favorites. Both teams have split wins in this series and the Cubs are putting Boyd on the mound who struggled in his first start of the season. Kikuchi had 2 earned runs in his first start of the season but there will be winds blowing in at game time and with both games of this series having gone under the total and both teams not hitting very well, I will go under the 6.5 runs in this one.

Nikos Lagouretos's Free Pick: Under 6.5

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