Angels vs Giants Prediction 4/19/25 MLB Picks Today

The San Francisco Giants and the Los Angeles Angels meet Saturday in MLB action from Angel Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Angels vs Giants Prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Landen Roupp for the start here and Roupp is 1-1 with a 4.80 ERA and 20 strikeouts this season. This will be Roupp’s first career start against the Angels. The Los Angeles Angels will trot out Kyle Hendricks for the start here and Hendricks is 0-1 with a 4.20 ERA and 9 strikeouts this season. In his last five starts against the Giants, Hendricks is 2-1 with a 2.25 ERA and 24 strikeouts.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to bounce back from a 2-0 loss at the hands of the Angels in Friday’s series opener to drop to 13-7 on the year. After this series, the Giants will head home for a series against the Milwaukee Brewers.

Giants Start Series On Wrong Foot

Jung Hoo Lee leads the Giants with 24 hits including a team-high 10 doubles along with 3 home runs and 14 RBIs with 3 stolen bases while Heliot Ramos has 18 hits with 6 doubles, 3 home runs and 9 RBIs. Wilmer Flores also has a team-high 6 home runs and 23 RBIs while Mike Yastrzemski has 3 home runs with 11 RBIs and 5 doubles and Tyler Fitzgerald has a team-high 4 stolen bases as well on the year.

Why the San Francisco Giants will win

• The Giants have won each of their last seven night games against American League opponents that held a winning record.
• The Angels have lost each of their last five night games at Angel Stadium of Anaheim following a win.
• The Giants have covered the run line each of their last seven night games against American League opponents that held a winning record.
• The Angels have failed to cover the run line in each of their last five night games at Angel Stadium of Anaheim following a win.

San Francisco Giants Player Prop Facts

• Mike Yastrzemski has recorded a Double in three of the Giants’ last four night games against opponents that held a winning record.
• Matt Chapman has hit a home run in each of his last two appearances at Angel Stadium of Anaheim against AL West opponents that held a winning record.
• Wilmer Flores has recorded at least one RBI in each of the Giants’ last five night games against opponents that held a winning record.
• Heliot Ramos has scored a run in each of the Giants’ last eight night games against AL opponents that held a winning record.
• Jung Hoo Lee has recorded at least one Single in each of the Giants’ last four games.
• Heliot Ramos has recorded at least one hit in each of the Giants’ last 10 games as favorites against AL opponents.
• Jung Hoo Lee ranks 5th amongst qualified players for Batting Average (.361) this season.

Los Angeles Angels Recap

The Los Angeles Angels will be out to build on their series-opening win over the Giants on Friday to improve to 10-9 on the year. After this series, the Angels will take on the Pittsburgh Pirates at home.

Angels Snap Losing Streak

Logan O’Hoppe has 16 hits including 5 home runs and 9 RBIs while Nolan Schanuel has 19 hits with 3 doubles, a triple, 2 home runs and 7 RBIs. Luis Rengifo has a team-high 5 doubles with his 16 hits and Taylor Ward also has 18 hits as well while Mike Trout’s added 6 home runs and 14 RBIs so far this season. Jorge Soler also has 4 home runs, but also has the unfortunate distinction of leading the Angels with 24 strikeouts so far this season. Kyren Paris has also chipped in 15 hits with a triple, 5 home runs and 8 RBIs.

Why the Los Angeles Angels will win

• The Giants have lost each of their last six Saturday games as road favorites.
• The Angels have won five of their last six games as home underdogs against NL West opponents.
• The home team has covered the run line in each of the Angels’ last five games.
• The Giants have failed to cover the run line in each of their last six Saturday games as road favorites.

Los Angeles Angels Player Prop Facts

• Logan O’Hoppe has hit a home run in three of the Angels’ last four games as home underdogs.
• Zach Neto has recorded at least one RBI in four of the Angels’ last five games as home underdogs against NL West opponents.
• Logan O’Hoppe has scored at least one run in six of his last seven appearances with the Angels as home underdogs.
• Kyle Hendricks has recorded four or more strikeouts in each of his last six home appearances against the Giants.
• Yoan Moncada has recorded a Double in three of his last four appearances with his team as a home underdog.
• Travis d’Arnaud has recorded a hit in each of his last 10 Saturday night appearances.
• Anthony Rendon has recorded at least one Single in seven of his last eight appearances against the Giants.
• Mike Trout ranks T6th in the league in Home Runs (6) this season.

Total Runs Facts

• Eight of the Giants’ last nine games have gone OVER the total runs line.
• Each of the Angels’ last four night games after playing the previous day have gone UNDER the total runs line.

Angels vs Giants Prediction

I’m on the Giants here. I think Landen Roupp has been one of the more unlucky pitchers, as he’s pitched well, it’s just been some bad luck to stick him with the ERA that he has up to this point in the year. The strikeouts have been there for Roupp, and I think he’ll be fine down the road. On the other side, the Angels managed to win, but it’s hard to get behind the Halos if they continue to struggle to drum up offense. I think the Giants can get the job done here and get their revenge in this matchup. Give me San Francisco here.