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Angels vs Orioles Prediction 6/22/26 MLB Picks Today

Baltimore Orioles (37-42) vs. LA Angels (32-47)
June 22, 2026 9:38 pm EDT
The Line: LA Angels 135 / Baltimore Orioles -163; Over/Under: 9
(Get latest betting odds)

The Baltimore Orioles and Los Angeles Angels meet Monday in MLB action at Angel Stadium. Here’s an Angels vs Orioles Prediction. This article will include an Angels vs Orioles Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 37-42 on the year and play the White Sox and Nationals next. The Baltimore Orioles are batting .241 on the season and have a .321 OBP and a .403 slugging percentage. The Baltimore Orioles pitching staff has a 4.45 ERA and a 1.39 WHIP. Pete Alonso leads the Baltimore Orioles with 74 hits and 52 RBI, while Gunnar Henderson and Taylor Ward have combined for 146 hits and 59 RBI.

Kyle Bradish gets the ball for the Baltimore Orioles, and he is 4-7 with a 4.00 ERA and 85 strikeouts this season. This will be Bradish’s second career game against the Los Angeles Angels.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 32-47 on the year and play the Athletics and Mariners next. The Los Angeles Angels are batting. 240 on the season, have a .320 OBP, and have a .401 slugging percentage. The Los Angeles Angels’ pitching staff has a 4.65 ERA and a 1.43 WHIP. Jo Adell leads the Los Angeles Angels with 77 hits and 41 RBI, while Zach Neto and Mike Trout have combined for 130 hits and 75 RBI.

Sam Aldegheri gets the ball for the Los Angeles Angels, and he is 2-2 with a 4.50 ERA and 13 strikeouts this season. This will be Aldegheri’s first career game against the Baltimore Orioles.

Why the Los Angeles Angels will win

  • The Orioles have lost four of their last five games as favorites against AL West opponents following a win.
  • The Angels have won three of their last four games as home underdogs.
  • The Orioles have failed to cover the run line in each of their last six games as favorites against AL West opponents following a road win.
  • The Angels have covered the run line in 10 of their last 11 games as home underdogs against American League opponents.
  • The Angels have won the first inning in three of their last four night games at Angel Stadium of Anaheim.
  • The Angels have led after 5 innings in each of their last nine night games at Angel Stadium of Anaheim against American League opponents.
  • The Orioles have trailed after 3 innings in seven of their last eight road games against AL West opponents that held a losing record.

Why the Baltimore Orioles will win

  • The Angels have lost each of their last eight games against the Orioles following a win.
  • The Orioles have won each of their last 13 Monday games against AL West opponents that held a losing record.
  • The Orioles have covered the run line each of their last 13 Monday games against AL West opponents that held a losing record.
  • The Angels have failed to cover the run line in each of their last seven games against the Orioles following a road win.
  • The Orioles have led after 5 innings in each of their last 11 Monday night games against AL West opponents that held a losing record.
  • The Orioles have led after 3 innings in each of their last nine Monday games against AL West opponents that held a losing record.
  • The Orioles have won the first inning in each of their last three night games against AL West opponents that held a losing record.

Total Runs Facts

  • Seven of the Angels’ last eight night games against AL East opponents have gone UNDER the total runs line.
  • Four of the Orioles’ last five games as favorites have gone OVER the total runs line.
  • There has been at least one run scored in the first inning in each of Samuel Aldegheri’s last five appearances as a starter.
  • There has been no run scored during the first inning in 13 of Kyle Bradish’s last 15 appearances as a starter.

Los Angeles Angels Player Prop Facts

  • Mike Trout has recorded at least one hit in each of his last 20 home appearances against AL East opponents that held a losing record.
  • Mike Trout has hit a home run in each of his last two home appearances against the Orioles.

Baltimore Orioles Player Prop Facts

  • Gunnar Henderson has hit a home run in four of the Orioles’ last five road games against the Angels.
  • Kyle Bradish has recorded seven or more strikeouts in seven of his last eight appearances against AL West opponents.
  • Taylor Ward has recorded at least one hit in each of his last 12 appearances with his team as a road favorite against AL opponents.
  • Taylor Ward ranks 10th amongst qualified players for On Base Percentage (.393) this season.

Matchup/League Facts

  • The Angels rank 30th in the league for strikeouts against this season (747).
  • The Angels rank 30th in the league for walks allowed this season (367).
  • The Orioles rank 28th in the league for strikeouts against this season (714).
  • The Orioles rank 28th in the league for opponent batting average this season (.257).

Angels vs Orioles Prediction

I’m looking at the over in this spot. The Angels are hot offensively, and the Orioles have pop in their lineup capable of producing crooked numbers. Through 81 innings, Bradish has a 4.00 ERA and 1.51 WHIP, while Aldegheri has a 4.50 ERA and 1.55 WHIP through 20 frames. Bradish has allowed 21 hits and 11 runs in his last 15.2 innings. He has a 5.09 ERA and a .326 allowed batting average in 35.1 innings on the road. Aldegheri just allowed 6 hits and 6 runs in 3 innings against the Diamondbacks. Expect some fireworks. Give me the over.

Randy Chambers's Free Pick: Over 9

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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