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Angels vs Pirates Prediction 4/22/25 MLB Picks Today

Pittsburgh Pirates (8-15) vs. LA Angels (11-10)
April 22, 2025 9:38 pm EDT
The Line: LA Angels -192 / Pittsburgh Pirates 160; Over/Under: 8.5
(Get latest betting odds)

The Pittsburgh Pirates and Los Angeles Angels meet Tuesday in MLB action at Angel Stadium. Here’s an Angels vs Pirates Prediction. This article will include an Angels vs Pirates Pick.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 8-15 on the year and play the Dodgers, Cubs, and Padres next. The Pittsburgh Pirates are batting .206 on the season, have a .289 OBP, and a .320 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 4.04 ERA and a 1.23 WHIP. Bryan Reynolds leads the Pittsburgh Pirates with 22 hits and 10 RBI, while Isiah Kiner-Falefa and Ke’Bryan Hayes have combined for 35 hits and 14 RBI.

Bailey Falter gets the ball for the Pittsburgh Pirates, and he is 1-2 with a 4.91 ERA and 15 strikeouts this season. This will be Falter’s first career game against the Los Angeles Angels.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 11-10 on the year and play the Twins, Mariners, and Tigers next. The Los Angeles Angels are batting .224 on the season, have a .285 OBP, and a .409 slugging percentage. The Los Angeles Angels’ pitching staff has a 4.35 ERA and a 1.36 WHIP. Nolan Schanuel leads the Los Angeles Angels with 21 hits and 7 RBI while Jorge Soler and Taylor Ward have combined for 39 hits and 17 RBI.

Jose Soriano gets the ball for the Los Angeles Angels, and he is 2-2 with a 3.16 ERA and 20 strikeouts this season. This will be Soriano’s second career game against the Pittsburgh Pirates.

Why the Los Angeles Angels will win

  • The Pirates have lost seven of their last eight road games.
  • The home team has won six of the Angels’ last seven games.
  • The Angels have covered the run line in each of their last five night games against National League opponents.
  • The Pirates have failed to cover the run line in each of their last four games.
  • The Angels have won the first inning in three of their last four games against opponents that held a losing record.
  • The Pirates have trailed after 3 innings in each of their last four games as road underdogs.
  • The Pirates have trailed after 5 innings in each of their last five night games against American League opponents.

Why the Pittsburgh Pirates will win

  • The Angels have lost each of their last six night games at Angel Stadium of Anaheim following a win.
  • The Pirates have won four of their last five games as underdogs following a home loss.
  • The Angels have failed to cover the run line in each of their last nine games as favorites.
  • The Pirates have covered the run line in each of their last eight games as underdogs following an extra-innings loss.
  • The Pirates have led after 5 innings in four of their last five games against AL West opponents that held a winning record.
  • The Angels have lost the first inning in three of their last four night games against NL Central opponents.
  • The Angels have trailed after 3 innings in four of their last five home games against National League opponents that held a losing record.

Los Angeles Angels Player Prop Facts

  • Taylor Ward has hit at least one home run in four of the Angels’ last five games against opponents that held a losing record.
  • Jorge Soler has recorded at least one RBI in seven of his last eight appearances against NL opponents that held a losing record.
  • Zach Neto has scored a run in seven of his last eight appearances in night games against NL Central teams that held a losing record.
  • Tim Anderson has recorded at least one Single in each of his last seven appearances against NL Central opponents.
  • Yoan Moncada has recorded a Double in each of his last three home appearances against opponents that held a losing record.
  • Yoan Moncada has recorded at least one hit in each of his last 14 home appearances against opponents that held a losing record.
  • Mike Trout ranks T3rd in the league in Home Runs (8) this season.

Pittsburgh Pirates Player Prop Facts

  • Oneil Cruz has hit a home run in each of the Pirates’ last two night games.
  • Joey Bart has scored at least one run in each of his last four appearances against AL West opponents that held a winning record.
  • Isiah Kiner-Falefa has recorded at least one Single in 14 of his last 15 appearances in night games against AL teams that held a winning record.
  • Tommy Pham has recorded at least one hit in each of his last 13 road appearances against AL West opponents that held a winning record.
  • Jared Triolo has recorded a Double in each of the Pirates’ last three road games against AL West opponents that held a winning record.
  • Jared Triolo has recorded at least one RBI in four of the Pirates’ last five road games against AL West opponents.
  • Oneil Cruz ranks 1st in the league in Steals (10) this season.

Angels vs Pirates Prediction

The Pirates continue to have issues finishing games, and they’re just not a team I’m excited to back, especially on the road. Falter is coming off seven shutout innings against the Nationals, but he’s still been average at best, with an ERA of nearly five on the season and similar numbers throughout his career. The Angels continue to hover around a .500 record, and Soriano is looking more and more like a young, promising pitcher. Soriano has a 3.16 ERA and 1.25 WHIP through 25.2 innings, making him an above-average starter up to this point. The price is insane, but I have to side with the Angels. Of course, I’ll lay the RL to shave down the juice.

Randy Chambers's Free Pick: LA Angels -1.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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