Angels vs Royals Prediction 9/24/25 MLB Picks Today

The Kansas City Royals and Los Angeles Angels meet Wednesday in MLB action at Angel Stadium. Here’s a Angels vs Royals Prediction. This article will include a Angels vs Royals Pick.

Kansas City Royals Betting Preview

The Kansas City Royals are 79-78 on the year and play the Athletics next. The Kansas City Royals are batting .248 on the season, have a .309 OBP, and a .397 slugging percentage. The Kansas City Royals pitching staff has a 3.76 ERA and a 1.25 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 176 hits and 84 RBI, while Maikel Garcia and Vinnie Pasquantino have combined for 327 hits and 180 RBI.

Stephen Kolek gets the ball for the Kansas City Royals, and he is 5-6 with a 3.54 ERA and 75 strikeouts this season. This will be Kolek’s first career game against the Los Angeles Angels.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 70-87 on the year and play the Astros next. The Los Angeles Angels are batting .226 on the season, have a .299 OBP, and a .398 slugging percentage. The Los Angeles Angels pitching staff has a 4.88 ERA and a 1.44 WHIP. Taylor Ward leads the Los Angeles Angels with 130 hits and 102 RBI while Zach Neto and Nolan Schanuel have combined for 257 hits and 114 RBI.

Yusei Kikuchi gets the ball for the Los Angeles Angels, and he is 6-11 with a 4.05 ERA and 168 strikeouts this season. Kikuchi is 3-2 with a 5.06 ERA and 42 strikeouts in his career against the Kansas City Royals.

Kansas City Royals @ Los Angeles Angels Betting Trends: September 24, 2025

• Probable Starting Pitcher: Yusei Kikuchi      Record this season: 6-11      ERA: 4.05
• Home Record: 5-3
• Last 5 against Royals: 3-0

Why the Los Angeles Angels will win

• The Royals have lost eight of their last nine games following a road win.
• The home team has won 11 of the Angels’ last 13 games.
• The Angels have covered the run line each of their last seven night games against AL Central opponents that held a winning record.
• The Royals have failed to cover the run line in five of their last six games as underdogs following a road win.
• The Royals have trailed after 5 innings in each of their last four games as underdogs against AL West opponents.
• The Royals have trailed after 3 innings in nine of their last 12 games as road underdogs against American League opponents.

• Probable Starting Pitcher: Stephen Kolek      Record this season: 5-6      ERA: 3.54
• Road Record: 3-2
• Last 5 against Angels: –

Why the Kansas City Royals will win

• The Angels have lost each of their last eight games against teams that held a winning record.
• The underdogs have won five of the Angels’ last seven games at Angel Stadium of Anaheim.
• The Royals have covered the run line in each of their last 10 Wednesday games as road underdogs.
• The Angels have failed to cover the run line in each of their last six games as home favorites.
• The Royals have led after 5 innings in each of their last seven Wednesday night games against opponents that held a losing record.
• The Royals have won the first inning in four of their last five road games.
• The Royals have led after 3 innings in eight of their last nine road games against AL West opponents.

Total Runs Facts

• Seven of the Angels’ last eight night games against American League opponents have gone OVER the total runs line.
• Each of the Royals’ last four road games have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Royals’ last eight road games.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Angels’ last seven games as home favorites against AL Central opponents.

Los Angeles Angels Player Prop Facts

• Yusei Kikuchi has recorded a win in three of his last four appearances against the Royals.
• Jo Adell has hit a home run in four of the Angels’ last five night games against AL Central opponents that held a winning record.
• Yoan Moncada has recorded a Double in three of his last four appearances against the Royals.
• Yusei Kikuchi has recorded five or more strikeouts in 14 of his last 16 appearances with his team as a home favorite against AL opponents.
• Yoan Moncada has recorded a hit in each of his last seven home appearances against the Royals.
• Jo Adell ranks 9th in the league in Home Runs (36) this season.

Kansas City Royals Player Prop Facts

• Salvador Perez has hit at least one home run in each of the Royals’ last two games as road underdogs.
• Vinnie Pasquantino has recorded at least one Double in each of the Royals’ last three road games.
• Vinnie Pasquantino has recorded at least one hit in each of the Royals’ last 10 night games.
• Bobby Witt Jr. ranks 3rd in the league in Hits (176) this season.

Matchup/League Facts

• The Angels rank 30th in the league for doubles this season (207).
• The Angels rank 30th in the league for batting average this season (.226).
• The Royals rank 1st in the league for strikeouts against this season (1056).
• The Royals rank 29th in the league for walks this season (418).

Angels vs Royals Prediction

The Royals are still mathematically in the playoff race, and that’s the edge in this game. Kolek has been strong since coming over from the Padres, allowing 15 hits and 5 earned runs in his last 27 innings. The Angels look like a team that’s excited for vacation, as the losses keep piling up, and they’ve won one game since September 11. Kikuchi hasn’t been great this season, and he’s allowed 23 hits and 15 runs in his last 19.1 innings. The Angels just don’t give much confidence these days. I have to side with the Royals on Wednesday night.