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Diamondbacks vs Tigers Prediction 4/1/26 MLB Picks Today

Detroit Tigers (2-3) vs. Arizona Diamondbacks (2-3)
April 1, 2026 3:40 pm EDT
The Line: Arizona Diamondbacks +139 / Detroit Tigers -168; Over/Under: 7.5
(Get latest betting odds)

The Detroit Tigers and the Arizona Diamondbacks meet Wednesday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Diamondbacks vs. Tigers Prediction.

Starting Pitching Matchup

The Detroit Tigers will send out Tarik Skubal for the start here and Skubal is 1-0 with a 0.00 ERA and 6 strikeouts this season. The Arizona Diamondbacks will send out Zac Gallen here and Gallen is 0-1 with a 9.00 ERA and 2 strikeouts this season.

Detroit Tigers Recap

The Detroit Tigers come into this game looking to rebound from their 7-5 loss at the hands of Arizona last time out to sit at 2-3 this season. After this series, the Tigers will head home for a set against the St. Louis Cardinals.

Tigers Lose 3 In A Row

Going into Tuesday’s matchup with Arizona, Dillon Dingler has 4 hits with a home run, a double and a team-high 5 RBIs, while Colt Keith’s added a team-high 6 hits with 3 doubles and 2 RBIs. Kevin McGonigle has added 5 hits with a pair of doubles and 4 RBIs and Spencer Torkelson has added 3 hits with a double and 3 RBIs as well this season. 

Why the Detroit Tigers will win

  • The Tigers have won each of their last seven day games against NL West opponents.
  • The Diamondbacks have lost seven of their last eight games after playing the previous day.
  • The Tigers have covered the run line in 10 of their last 11 day games against NL West opponents following a road loss.
  • The Diamondbacks have failed to cover the run line in four of their last five home games against American League opponents that held a losing record.

Detroit Tigers Player Prop Facts

  • Tarik Skubal has recorded a win in four of his last five appearances against NL opponents.
  • Matt Vierling has recorded at least one hit in each of his last eight appearances with his team as a road favorite against NL West opponents.
  • Tarik Skubal has recorded eight or more strikeouts in five of his last six appearances.
  • Jake Rogers has hit a home run in each of his last two appearances in day games against NL teams that held a losing record.
  • Tarik Skubal ranks 1st amongst qualified players for Earned Run Average (0.00) this season.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to add on to their win over the Tigers from Tuesday to push their record to 2-3 on the year. After this series, Arizona will take on the Atlanta Braves at home.

Diamondbacks Nab Back-To-Back Wins

Entering Tuesday, Corbin Carroll leads the Diamondbacks with 4 hits, including a triple, a home run and a team-high 5 RBIs, while Alek Thomas has logged 3 doubles with 4 RBIs as well this season. Ketel Marte and Geraldo Perdomo each have 4 hits with a home run and 2 RBIs, with Perdomo logging a double as well this season. 

Why the Arizona Diamondbacks will win

  • The Tigers have lost each of their last seven games as favorites after playing the previous day.
  • The home team has won each of the Diamondbacks’ last eight games.
  • The Diamondbacks have covered the run line in each of their last 11 games as underdogs against American League opponents.
  • The Tigers have failed to cover the run line in each of their last seven games as favorites after playing the previous day.

Arizona Diamondbacks Player Prop Facts

  • Zac Gallen has recorded a win in each of his last three home appearances.
  • Zac Gallen has recorded seven or more strikeouts in three of his last four home appearances against AL Central opponents.
  • Ildemaro Vargas has hit a home run in each of his last two home appearances against the Tigers.
  • Geraldo Perdomo has recorded at least one hit in each of the Diamondbacks’ last eight games as underdogs.

Total Runs Facts

  • Each of the last seven games between the Tigers and Diamondbacks at Chase Field has gone OVER the total runs line.
  • Nine of the Tigers’ last 11 road games against NL West opponents have gone OVER the total runs line.

Diamondbacks vs Tigers Prediction

I’m on the Tigers here. I think Detroit has a seismic edge in starting pitching with Tarik Skubal starting here, as he’s one of the best starters in baseball and is Detroit’s stopper. Arizona has found a couple of solid wins, but I think Detroit avoids the sweep with a win here.

Chris Ruffolo's Free Pick: Detroit Tigers -168

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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