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Arizona Diamondbacks vs NY Yankees Prediction 9/20/26 MLB Picks Today

NY Yankees (89-65) vs. Arizona Diamondbacks (81-74)
September 20, 2026 4:10 pm EDT
The Line: Arizona Diamondbacks -105 / NY Yankees -114; Over/Under: 8.5
(Get latest betting odds)

The New York Yankees and the Arizona Diamondbacks meet Sunday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Yankees vs. Arizona Diamondbacks prediction.

Starting Pitching Matchup

The New York Yankees will send out Will Warren for the start here and Warren is 10-6 with a 3.89 ERA and 147 strikeouts this season. Corbin Burnes will start for the Diamondbacks here and Burnes is 0-0 with a 5.87 ERA and 6 strikeouts this season.

New York Yankees Recap

The New York Yankees come into this game looking to bounce back from a 5-3 loss at the hands of the Arizona Diamondbacks last time out to sit at 89-65 this season. After this series, New York will head home for a series against the Tampa Bay Rays.

Yankees Alternate Wins & Losses In 5 Straight

Ben Rice leads the Yankees with a team-high 144 hits, 39 home runs, and 94 RBIs while adding 22 doubles and 4 triples so far this season. Cody Bellinger has added 130 hits with 25 doubles, 3 triples, 16 home runs, and 71 RBIs, while Jazz Chisholm Jr. has chipped in 107 hits with 16 doubles, 3 triples, 19 home runs, and 55 RBIs. Jose Caballero has logged 92 hits with 13 doubles, 14 home runs, and 51 RBIs, while Trent Grisham has contributed 88 hits with 19 doubles, 2 triples, 18 home runs, and 59 RBIs for New York. Aaron Judge has also recorded 57 hits with 10 doubles, 18 home runs, and 41 RBIs on the year.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to add on to their win over New York last time out to sit at 80-75 on the year. After this series, the Diamondbacks will head on the road for a series against the Rockies.

Diamondbacks Snap Three-Game Slide

Gabriel Moreno leads the Diamondbacks with a team-high 136 hits and 75 RBIs while adding 32 doubles, a triple, and 15 home runs so far this season. Geraldo Perdomo has added 135 hits with 19 doubles, 6 triples, 9 home runs, and 50 RBIs, while Corbin Carroll has logged 133 hits with 31 doubles, 16 triples, 22 home runs, and 69 RBIs on the year. Ketel Marte has contributed 132 hits with 29 doubles, 3 triples, 22 home runs, and 74 RBIs, Nolan Arenado leads Arizona with a team-high 26 home runs alongside 123 hits, 23 doubles, a triple, and 74 RBIs, and Ildemaro Vargas has chipped in 111 hits with 19 doubles, 5 triples, 9 home runs, and 67 RBIs up to this point in the season.

New York Yankees @ Arizona Diamondbacks Betting Trends: September 20, 2026

 

  • Probable Starting Pitcher: Corbin Burnes      Record this season: 0-0      ERA: 5.87
  • Home Record: 0-0
  • Last 5 against Yankees: 0-2

Why the Arizona Diamondbacks will win

  • The Diamondbacks have won seven of their last eight games as underdogs after playing the previous day.
  • The Yankees have lost four of their last seven games as road favorites against NL West opponents.
  • The underdogs have covered the run line in each of the Diamondbacks’ last seven games.
  • The Yankees have failed to cover the run line in each of their last three games as road favorites against NL opponents.
  • The Yankees have lost the first inning in three of their last four day games.
  • The Diamondbacks have led after 5 innings in six of their last seven home games against AL opponents that held a winning record.
  • The Diamondbacks have led after 3 innings in each of their last three day games against the Yankees.

 

  • Probable Starting Pitcher: Will Warren      Record this season: 10-6      ERA: 3.89
  • Road Record: 4-3
  • Last 5 against Diamondbacks: 0-0

Why the New York Yankees will win

  • The Yankees have won each of their last 10 games following a loss.
  • The Diamondbacks have lost seven of their last eight games following a home win.
  • The Yankees have covered the run line in each of their last six games following a loss.
  • The Diamondbacks have failed to cover the run line in seven of their last eight games following a home win.
  • The Diamondbacks have lost the first inning in each of their last three day games against AL opponents that held a winning record.
  • The Yankees have led after 5 innings in four of their last five games against NL West opponents.
  • The Diamondbacks have trailed after 3 innings in five of their last six games against AL East opponents.

Total Runs Facts

  • Eight of the Yankees’ last nine games have gone OVER the total runs line.
  • Each of the Diamondbacks’ last five games against AL East opponents have gone OVER the total runs line.
  • There has been no run scored during the first inning in each of the Yankees’ last five games as road favorites against NL West opponents.
  • There has been no run scored during the first inning in each of Corbin Burnes’ four previous appearances as a starter against the Yankees.

Arizona Diamondbacks Player Prop Facts

  • Pavin Smith has hit a home run in two of the Diamondbacks’ last three games.
  • Corbin Burnes has recorded five or more strikeouts in each of his nine previous appearances against AL East opponents that held a winning record.
  • Nolan Arenado has recorded at least one hit in each of his last 17 appearances against the Yankees.
  • Gabriel Moreno ranks 5th amongst qualified players for Batting Average (.304) this season.

New York Yankees Player Prop Facts

  • Will Warren has recorded five or more strikeouts in four of his last five road appearances.
  • Paul Goldschmidt has recorded at least one hit in each of his eight previous appearances with his team as a road favorite against the Diamondbacks.
  • Aaron Judge has hit at least one home run in four of his last five appearances with the Yankees as road favorites against NL West opponents.
  • Will Warren has recorded a win in each of his last three appearances in day games against teams that held a winning record.
  • Luis Garcia ranks 3rd amongst qualified players for Slugging Percentage (.534) this season.

Matchup/League Facts

  • The Diamondbacks rank 2nd in the league for triples this season (37).
  • The Diamondbacks rank 29th in the league for strikeouts this season (1086).
  • The Yankees rank 1st in the league for ERA this season (3.18).
  • The Yankees rank 1st in the league for runs allowed this season (568).

New York Yankees vs. Arizona Diamondbacks Prediction

I’m backing the Yankees in this one. Burnes has given up some damage in his limited action this season and I think the Yankees get the series win here. New York has been able to back up Warren and Warren’s been a solid option for New York for much of the season and I look for that to continue here. Give me New York.

Chris Ruffolo's Free Pick: NY Yankees -114

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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