Arizona Diamondbacks vs Washington Nationals Prediction 6/5/26 MLB Picks Today

The Washington Nationals and the Arizona Diamondbacks meet Friday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Washington Nationals vs. Arizona Diamondbacks prediction.

Starting Pitching Matchup

The Washington Nationals will send out Foster Griffin here and Griffin is 6-2 with a 3.76 ERA and 65 strikeouts this season. This will be Griffin’s first career start against the Diamondbacks. Merrill Kelly will start for Arizona and is 5-3 with a 5.06 ERA and 33 strikeouts this season. In his career, Kelly is 3-0 with a 4.50 ERA and 26 strikeouts against the Nationals.

Washington Nationals Recap

The Washington Nationals come into this game looking to bounce back from a 4-1 loss at the hands of the Miami Marlins last time out to sit at 31-32 this season. After this series, the Nationals will head on the road for a series against the San Francisco Giants.

Nationals Lose 3 Straight

James Wood has 63 hits with 15 doubles, 16 home runs and 39 RBIs while CJ Abrams has 65 hits with 13 doubles, 12 home runs and 47 RBIs. Daylen Lile has 62 hits with 15 doubles, 7 home runs and 28 RBIs and Luis Garcia Jr. has 49 hits with 10 doubles, 3 triples, 5 home runs and 31 RBIs. Jacob Young has 46 hits with 8 home runs and 27 RBIs.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to add on to their 3-2 win over the Los Angeles Dodgers last time out to sit at 33-29 this season. After this series, the Diamondbacks will head on the road for a series against the Miami Marlins.

Diamondbacks Snap Two-Game Slide

Corbin Carroll has 64 hits including 15 doubles, 8 triples, 9 home runs and 30 RBIs. Ketel Marte has 60 hits with 11 doubles, 11 home runs and 37 RBIs and Geraldo Perdomo has 47 hits, with 9 doubles, 3 triples, 3 home runs and 22 RBIs as well this season. Nolan Arenado also has 50 hits with 12 doubles, 8 home runs and 30 RBIs and Jose Fernandez has 42 hits with 3 home runs and 15 RBIs this season. Ildemaro Vargas also has 60 hits with 9 doubles, 2 triples, 7 home runs and 37 RBIs.

Washington Nationals @ Arizona Diamondbacks Betting Trends: June 5, 2026

• Probable Starting Pitcher: Merrill Kelly      Record this season: 5-3      ERA: 5.06
• Home Record: 2-1
• Last 5 against Nationals: 3-0

Why the Arizona Diamondbacks will win

• The Diamondbacks have won each of their last seven night games against the Nationals following a win.
• The Nationals have lost each of their last seven night games against the Diamondbacks following a loss.
• The Diamondbacks have covered the run line in nine of their last 10 games against NL East opponents.
• The Nationals have failed to cover the run line in four of their last five night games against NL West opponents.
• The Diamondbacks have led after 5 innings in five of their last six games against National League opponents that held a losing record.
• The Diamondbacks have led after 3 innings in five of their last six games against National League opponents that held a losing record.

• Probable Starting Pitcher: Foster Griffin      Record this season: 6-2      ERA: 3.76
• Road Record: 4-1
• Last 5 against Diamondbacks: –

Why the Washington Nationals will win

• The underdogs have won five of the Nationals’ last six games.
• The Diamondbacks have lost three of their last four games as home favorites against NL East opponents following a win.
• The Nationals have covered the run line in 15 of their last 16 road games following a loss.
• The Diamondbacks have failed to cover the run line in each of their last six Friday home games against NL East opponents.
• The Diamondbacks have trailed after 5 innings in each of their last eight games.
• The Diamondbacks have trailed after 3 innings in seven of their last eight games.

Total Runs Facts

• Each of the Nationals’ last nine night games against National League opponents have gone OVER the total runs line.
• Seven of the last eight games between the Nationals and Diamondbacks at Chase Field have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last 11 night games between the Nationals and Diamondbacks.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Nationals’ last seven games as underdogs against National League opponents.

Arizona Diamondbacks Player Prop Facts

• Corbin Carroll has hit a home run in two of the Diamondbacks’ last three games.
• Merrill Kelly has recorded a win in each of his last four appearances against NL opponents.
• Merrill Kelly has recorded five or more strikeouts in each of his four previous appearances against the Nationals.
• James McCann has recorded at least one hit in each of his last 12 appearances with his team as a favorite against NL East opponents.
• Corbin Carroll ranks 5th amongst qualified players for Slugging Percentage (.557) this season.

Washington Nationals Player Prop Facts

• Keibert Ruiz has hit a home run in each of his last two appearances in night games against NL teams that held a winning record.
• Keibert Ruiz has recorded at least one hit in each of his last eight appearances after not playing the previous day.
• Nasim Nunez ranks T1st in the league in Steals (22) this season.

Matchup/League Facts

• The Diamondbacks rank 1st in the league for triples this season (17).
• The Diamondbacks rank 30th in the league for strikeouts this season (439).
• The Nationals rank 1st in the league for runs scored this season (331).
• The Nationals rank 30th in the league for home runs allowed this season (90).

Washington Nationals vs. Arizona Diamondbacks Prediction

I’m on the over in this game. I get the case to be made for either side, but I still think this Nationals team has a lot of upside offensively and while Merrill Kelly’s pitched well, he can still be had here. On the flipside, Foster Griffin’s been a profitable option for Washington this season, but the fact is that the Diamondbacks have hit lefties well in their own right and I think we get up and over this total here.