Astros vs Angels Prediction 4/13/25 MLB Picks Today

The Los Angeles Angels and the Houston Astros meet Sunday in MLB action from Daikin Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Astros vs Angels Prediction.

Starting Pitching Matchup

The Los Angeles Angels will send out Kyle Hendricks for the start in this one and Hendricks is 0-0 with a 1.64 ERA and 8 strikeouts this season. This will be Hendricks’ second career start against the Astros. Hayden Wesneski will get the nod for the Astros here and Wesneski is 0-1 with a 3.75 ERA and 11 strikeouts this season. In his career, Wesneski is 1-0 with a 1.64 ERA and 6 strikeouts against the Angels.

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to add on to their 4-1 win over the Astros from Saturday’s matchup. After this set, the Angels will head on the road for another division series against the Texas Rangers.

Angels Win 6 Of Their Last 8

Logan O’Hoppe has 14 hits including a team-high 5 home runs and 9 RBIs while Nolan Schanuel has 14 hits with 3 doubles, a triple and 5 RBIs. Luis Rengifo has a team-high 4 doubles with his 11 hits and Taylor Ward also has 12 hits as well while Mike Trout’s added 6 home runs and 12 RBIs so far this season. Jorge Soler also has 3 home runs, but also has the unfortunate distinction of leading the Angels with 18 strikeouts so far this season. Kyren Paris has also chipped in 13 hits with a triple, 5 home runs and 8 RBIs.

Why the Los Angeles Angels will win

• The Astros have lost five of their last six games as favorites after playing the previous day.
• The underdogs have won three of the Astros’ last four games.
• The Astros have failed to cover the run line in each of their last 10 home games after playing the previous day.
• The Angels have covered the run line in seven of their last eight day games against AL West opponents following a win.

Los Angeles Angels Player Prop Facts

• Taylor Ward has hit at least one home run in three of the Angels’ last four games as underdogs.
• Taylor Ward has recorded at least one Single in each of the Angels’ last five day games.
• Nolan Schanuel has recorded at least one hit in each of the Angels’ last 15 games as road underdogs.
• Kyle Hendricks has recorded three or more strikeouts in each of his nine previous road appearances against AL opponents that held a losing record.
• Anthony Rendon has recorded an RBI in seven of his last eight appearances in day games against AL West teams that held a losing record.
• Anthony Rendon has scored a run in each of his last six appearances with the Angels as underdogs against the Astros.
• Mike Trout ranks T1st in the league in Home Runs (6) this season.

Houston Astros Recap

The Houston Astros will look to bounce back from their loss to the Angels on Saturday that evened up the series at one win apiece. After this series, the Astros will head on the road for a series against the St. Louis Cardinals.

Astros Searching For Consistent Play After Alternating Wins & Losses In 9 Straight Games

Jose Altuve leads the Astros with 19 hits including 3 home runs and 6 RBIs. Jeremy Pena also has a pair of homers and 4 stolen bases while Yordan Alvarez has a double and a team-high 9 RBIs with 13 strikeouts as well. Brendan Rodgers has a pair of doubles while Jake Meyers has a pair of doubles as well and Christian Walker has also accrued a team-high 18 strikeouts so far this season. Altuve also has 3 stolen bases while Jake Meyers has a team-high 5 stolen bases this season.

Why the Houston Astros will win

• The Astros have won each of their last nine games against the Angels following a loss.
• The Angels have lost 13 of their last 14 games against the Astros following a win.
• The Astros have covered the run line in each of their last six day games against the Angels at Daikin Park following a loss.
• The Angels have failed to cover the run line in eight of their last nine games against American League opponents following a road win.

Houston Astros Player Prop Facts

• Isaac Paredes has hit at least one home run in three of his last four appearances at Daikin Park against AL West opponents that held a winning record.
• Yordan Alvarez has recorded a Double in three of his last four home appearances against AL West opponents.
• Victor Caratini has recorded at least one RBI in each of his last four appearances in day games against AL West teams that held a winning record.
• Jeremy Pena has recorded at least one Single in 11 of the Astros’ last 12 games against the Angels.
• Jeremy Pena has recorded at least one hit in each of his last 18 appearances against the Angels.
• Yainer Diaz has scored at least one run in five of the Astros’ last six games against the Angels.
• Jose Altuve ranks T7th in the league in Hits (19) this season.

Total Runs Facts

• Each of the Astros’ last eight day games against AL West opponents have gone OVER the total runs line.
• Six of the Angels’ last seven road games after playing the previous day have gone OVER the total runs line.

Astros vs Angels Prediction

I’m on the over in this game. Hendricks has never really been a reliable starting option for me as far as I’m concerned, and Hayden Wesneski has been an average reliever/spot starter at best over the course of his brief major league career. These two offenses have started to show some life over the last week, the Angels more so since the start of the season, and I think we’re going to have some more offensive fireworks to close out the series. Give me the over in this one.