Astros vs Angels Prediction 7/29/26 MLB Picks Today

In this article, we will formulate an Astros vs Angels Prediction for this MLB matchup on Wednesday, July 29^th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Angels Preview

The Los Angeles Angels have a 42-66 record this season and are sitting in the 5th place of the AL West. They have a 24-30 home record and are coming off a 2-3 home loss against the Astros. They will face the Brewers and the Orioles next.

The Los Angeles Angels have a .239 batting average this season, .315 OBP and .386 Slugging percentage. Los Angeles’s pitching staff has a 4.52 ERA and 1.37 WHIP. Nolan Schanuel is the team’s best hitter with a .279 batting average. Jo Adell leads the team in RBI with 60, while Zach Neto adds a team-high 19 home runs.

Grayson Rodriguez (R) is the projected starting pitcher for the Los Angeles Angels, and he has a 3-3 record, 8.54 ERA and 1.79 WHIP.

Houston Astros Preview

The Houston Astros have a 54-55 record this season and are sitting in the 2nd place of the AL West. They have a 28-28 away record and are coming off a 3-2 road win against the Angels. They will face the Rangers and the Padres next.

The Houston Astros have a .241 batting average this season, .316 OBP and .411 Slugging percentage. Houston’s pitching staff has a 4.70 ERA and 1.38 WHIP. Yordan Alvarez is the team’s best hitter with a .325 batting average, leads the team in RBI with 80, and adds a team-high 35 home runs.

Hayden Wesneski is the projected starting pitcher for the Houston Astros and he will make his season debut. Last season he had a 1.3 record, 4.50 ERA and 1.09 WHIP.

Houston Astros @ Los Angeles Angels Betting Trends: July 29, 2026

• Probable Starting Pitcher: Grayson Rodriguez      Record this season: 3-3      ERA: 8.54
• Home Record: 1-3
• Last 5 against Astros: 0-1

Why the Los Angeles Angels will win

• The Astros have lost seven of their last nine games as favorites against AL West opponents following a road win.
• The Angels have won nine of their last 12 games as home underdogs against AL West opponents following a home loss.
• The Astros have failed to cover the run line in each of their last six games as road favorites against AL West opponents.
• The Angels have covered the run line in each of their last six games as home underdogs against AL West opponents following a loss.
• The Angels have won the first inning in three of their last four games against the Astros.
• The Angels have led after 3 innings in six of their last seven night games against the Astros.
• The Astros have trailed after 5 innings in nine of their last 10 games as road favorites.

• Probable Starting Pitcher: Hayden Wesneski       Record this season: –      ERA: –
• Road Record: –
• Last 5 against Angels: 2-0

Why the Houston Astros will win

• The Astros have won each of their last seven night games after playing the previous day.
• The Angels have lost seven of their last eight games against AL West opponents.
• The Angels have failed to cover the run line in four of their last five games after playing the previous day.
• The Astros have covered the run line in four of their last five night games following a win.
• The Angels have lost the first inning in each of their last three games as underdogs against American League opponents.
• The Angels have trailed after 3 innings in three of their last four games as underdogs.
• The Angels have trailed after 5 innings in three of their last four games as underdogs.

Total Runs Facts

• Each of the Angels’ last seven games as underdogs against American League opponents have gone UNDER the total runs line.
• Five of the Astros’ last six games as favorites have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in each of the Angels’ last 10 night games against American League opponents.
• There has been at least one run scored in the first inning in 12 of the Astros’ last 13 night games against AL West opponents.

Los Angeles Angels Player Prop Facts

• Vaughn Grissom has hit a home run in two of the Angels’ last three night games.
• Grayson Rodriguez has recorded a win in four of his last five appearances against AL West opponents.
• Grayson Rodriguez has recorded five or more strikeouts in each of his last nine appearances against AL West opponents.
• Vaughn Grissom has recorded at least one hit in each of the Angels’ last 10 night games.
• Mike Trout ranks 5th amongst qualified players for On Base Percentage (.394) this season.

Houston Astros Player Prop Facts

• Jeremy Pena has hit a home run in three of the Astros’ last four games as favorites.
• Hayden Wesneski has recorded a win in each of his last three appearances with his team as a favorite against AL West opponents.
• Yordan Alvarez has recorded two or more hits in each of the Astros’ last four games as favorites.
• Yordan Alvarez ranks 1st in the league in Home Runs (35) this season.

Matchup/League Facts

• The Angels rank 29th in the league for strikeouts against this season (1022).
• The Angels rank 29th in the league for strikeouts against this season (1022).
• The Astros rank 30th in the league for walks allowed this season (469).
• The Astros rank 30th in the league for walks allowed this season (469).

Astros vs Angels Prediction

The Astros Jays are 5-2 in their last 7 meetings against the Angels and have won their last two visits in Los Angeles.

In this Astros vs Angels Prediction, the Astros are coming as -130 road favorites. I have to go with the Astros in this one in a very good price, even though I don’t trust Hayden Wesneski in his season debut. This is just a fade of a bad Angels team that is 1-5 in its last 6 games and also fade of the struggling Grayson Rodriguez and his abysmal 8.54 ERA and 1.79 WHIP. He has been in terrible shape with 11 earned runs in his last two starts and somehow he is even worse at home with a 1-3 record and 10.22 ERA. Take the Astros to win this one.