
Astros vs Guardians Prediction 7/7/25 MLB Picks Today
Cleveland Guardians (40-48) vs. Houston Astros (55-35)
July 7, 2025 8:10 pm EDT
The Line: Houston Astros -164 / Cleveland Guardians 134; Over/Under: 7.5
(Get latest betting odds)
In this article, we will formulate an Astros vs Guardians prediction for this MLB game on Monday, July 7th at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup.
Houston Astros Betting Preview
The Houston Astros are 55-35 this season after they swept the Dodgers by scores of 18-1, 6-4, and 5-1. In their game three win, Houston trailed 1-0 early in the game, but they scored the final five runs in the game for the victory. The Astros recorded 11 hits in the game, and they were led by Altuve, who went 2-4 with one home run and two RBIs in the win. Houston started Gusto, who allowed four hits and one earned run over 6.0 innings for the win, while Sousa and King both picked up a hold.
Prior to that series, the Astros won two out of three against the Rockies and two out of three against the Cubs. Houston has won 11 of their last 13 games, and they are currently first in the AL West standings. The Houston pitching staff has a 3.48 ERA with a 1.16 WHIP and a .223 opponent batting average, while their offense has scored 396 runs with a .261 batting average and a .326 on-base percentage this season. Isaac Paredes has led Houston with 18 home runs and 48 RBIs, while Jose Altuve has added 16 home runs and 46 RBIs this year. The projected starting pitcher for Houston is Hunter Brown, who is 9-3 with a 1.82 ERA and a 0.90 WHIP over 104.0 innings pitched this season.
Cleveland Guardians Betting Preview
The Cleveland Guardians are 40-48 this year after they lost all three games against Detroit by scores of 1-2, 0-1, and 2-7. In their game three loss, Cleveland led 1-0 in the eighth inning, but they blew the save in the ninth and allowed six runs in the 10th for the loss. The Guardians recorded six hits and they committed two errors in the game, while they were led by Kwan, who went 3-4 with two RBIs in the loss. Cleveland started Williams, who allowed one hit and zero earned runs over 6.0 innings, while Clase blew the save and Smith picked up the loss.
Prior to that series, the Guardians lost all three against the Cubs and all three against the Cardinals. Cleveland has lost 10 games in a row, and they are currently fourth in the AL Central standings. The Cleveland pitching staff has a 3.96 ERA with a 1.36 WHIP and a .249 opponent batting average, while the offense has scored 312 runs with a .224 batting average and a .295 on-base percentage this season. Jose Ramirez has led Cleveland with 14 home runs and 39 RBIs, while Kyle Manzardo has added 13 home runs and 33 RBIs this year. The projected starting pitcher for Cleveland is Tanner Bibee, who is 4-9 with a 4.20 ERA and a 1.24 WHIP over 98.2 innings pitched this year.
Why the Astros will beat the Guardians
- The Guardians have lost each of their last 10 games.
- The Astros have won 10 of their last 11 games at Daikin Park.
- The Guardians have failed to cover the run line in five of their last six games as underdogs against AL West opponents.
- The Astros have covered the run line in five of their last six games against the Guardians.
- The Guardians have trailed after 5 innings in five of their last six night games against opponents that held a winning record.
- The Astros have led after 3 innings in six of their last seven home night games.
Total Runs Facts
- Nine of the Guardians’ last 10 road games have gone UNDER the total runs line.
- Five of the Astros’ last six games against American League opponents have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in nine of the Astros’ last 10 games as favorites against AL Central opponents.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Guardians’ last nine games as underdogs against AL West opponents.
Houston Astros Player Prop Facts
- Christian Walker has hit a home run in each of his last two home appearances against the Guardians.
- Jose Altuve has recorded at least one hit in each of his last 11 home appearances against the Guardians.
- Yainer Diaz has recorded a Double in three of the Astros’ last four night games against AL Central opponents that held a losing record.
Cleveland Guardians Player Prop Facts
- Lane Thomas has hit a home run in two of his last three appearances in night games against AL teams that held a winning record.
- Steven Kwan has recorded a Double in three of the Guardians’ last four games against AL opponents.
- Lane Thomas has recorded at least one hit in each of his last six road appearances against AL West opponents that held a winning record.
Astros vs Guardians Prediction
These two teams come into this matchup trending in opposite directions, as Houston is red hot right now, while Cleveland is trying to avoid an 11th straight loss. The Astros are 32-14 at home this year, while the Guardians are 20-25 on the road. Cleveland has scored a total of three runs in their last four games, and they are facing Brown, who has allowed two earned runs or fewer in five straight starts. Cleveland is starting Bibee, who has allowed five earned runs in two of his last three. Take Houston to win this game by at least two runs.