Astros vs Mariners Prediction 4/12/26 MLB Picks Today

In this article, we will formulate an Astros vs Mariners Prediction for this MLB matchup on Sunday, April 12th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Preview

The Seattle Mariners have a 6-9 record this season and are sitting in the fourth place of the AL West. They have a 5-4 home record and are coming off an 8-7 home win against the Astros. Their previous three games were a 9-6 home win against the Astros, and a 3-0 and a 3-2 road loss against the Rangers.

The Mariners have a .193 batting average this season, .302 OBP and .323 Slugging percentage. Seattle’s pitching staff has a 3.14 ERA and 1.07 WHIP. Cole Young is the team’s best hitter with a .269 batting average. Cal Raleigh leads the team in RBI with 10, and Luke Raley adds a team‑high 3 home runs.

George Kirby (R) is the projected starting pitcher for the Mariners, and he has a 1-2 record, 3.60 ERA and 0.90 WHIP.

Houston Astros Preview

The Houston Astros have a 6-9 record this season and are sitting in the fourth place of the AL West. They have a 1-7 away record and are coming off an 7-8 road loss against the Mariners. Their previous three games were a 9-6 road loss against the Mariners, and a 9-1 and a 5-1 road loss against the Rockies.

The Astros have a .281 batting average this season, .377 OBP and .462 Slugging percentage. Houston’s pitching staff has a 6.47 ERA and 1.68 WHIP. Yordan Alvarez is the team’s best hitter with a .360 batting average, also adding a team-high 6 home runs and leading the team in RBI with 14.

Mike Burrows (R) is the projected starting pitcher for the Astros, and he has a 1-2 record, 5.63 ERA and 1.75 WHIP.

Houston Astros @ Seattle Mariners Betting Trends: April 12, 2026

• Probable Starting Pitcher: Logan Gilbert      Record this season: 0-2      ERA: 5.40
• Home Record: 0-1
• Last 5 against Astros: 2-2

Why the Seattle Mariners will win

• The Mariners have won each of their last 12 home games against teams that held a losing record.
• The Astros have lost each of their last six games.
• The Mariners have covered the run line in each of their last six Sunday home games against American League opponents.
• The Astros have failed to cover the run line in five of their last six games.
• The Mariners have led after 3 innings in each of their last six Sunday games against the Astros.
• The Mariners have won the first inning in each of their last four home games against AL West opponents.
• The Astros have trailed after 5 innings in five of their last six games.

• Probable Starting Pitcher: Cody Bolton      Record this season: 0-0      ERA: 3.68
• Road Record: 0-0
• Last 5 against Mariners: –

Why the Houston Astros will win

• The Astros have won each of their last 11 day games against AL West opponents following a road loss.
• The Mariners have lost five of their last six games as favorites after playing the previous day.
• The Mariners have failed to cover the run line in each of their last six games as favorites after playing the previous day.
• The Astros have covered the run line in 11 of their last 12 games as underdogs following a road loss.
• The Astros have led after 5 innings in five of their last six day games against American League opponents that held a losing record.
• The Mariners have trailed after 3 innings in three of their last four home games.

Total Runs Facts

• Each of the Astros’ last 10 games against American League opponents have gone OVER the total runs line.
• Eight of the Mariners’ last nine games as home favorites have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last six games as underdogs.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last six day games between the Astros and Mariners at T-Mobile Park.

Seattle Mariners Player Prop Facts

• Cal Raleigh has hit a home run in three of the Mariners’ last four games against the Astros.
• Logan Gilbert has recorded seven or more strikeouts in each of his last nine home appearances against AL West opponents.
• Victor Robles has recorded at least one hit in each of his last nine appearances in day games against teams that held a losing record.
• Logan Gilbert has recorded a win in three of his last four appearances with the Mariners as favorites against AL opponents.

Houston Astros Player Prop Facts

• Yordan Alvarez has hit a home run in each of the Astros’ last three games against AL West opponents.
• Jose Altuve has recorded at least one hit in each of his last 18 road appearances against the Mariners after playing the previous day.
• Yordan Alvarez ranks T1st in the league in Home Runs (6) this season.

Matchup/League Facts

• The Mariners rank 29th in the league for batting average this season (.193).
• The Mariners rank 29th in the league for slugging percentage this season (.323).
• The Astros rank 1st in the league for runs scored this season (92).
• The Astros rank 1st in the league for hits this season (147).

Astros vs Mariners Prediction

The Mariners are 7-1 in their last 8 meetings against the Astros and are 4-1 in their last 5 meetings in Seattle.

In this Astros vs Mariners Prediction, the Mariners are coming as -155 home favorites. The Astros have been struggling mightily with six consecutive wins and have at least 8 earned runs in five of their last six games. Things will not get any better with Burrows on the mound who has been hittable this season and the Astros have the worst bullpen currently in baseball to back him up. Kirby has not been looking good for the Mariners lately and both teams are way better against righties, with 11.5 runs/9. Both games in this series had 15 total runs each, so I expect another high-scoring affair today. Take the over 7.5.