Astros vs Rangers Prediction 9/15/25 MLB Picks Today

The Texas Rangers and Houston Astros meet Monday in MLB action at Daikin Park. Here’s a Astros vs Rangers Prediction. This article will include a Astros vs Rangers Pick.

Texas Rangers Betting Preview

The Texas Rangers are 79-71 on the year and play the Marlins, Twins, and Guardians next. The Texas Rangers are batting .237 on the season, have a .306 OBP, and a .387 slugging percentage. The Texas Rangers pitching staff has a 3.42 ERA and a 1.17 WHIP. Josh Smith leads the Texas Rangers with 121 hits and 33 RBI, while Wyatt Langford and Adolis Garcia have combined for 227 hits and 134 RBI.

Jack Leiter gets the ball for the Texas Rangers, and he is 9-8 with a 3.81 ERA and 130 strikeouts this season. Leiter is 1-0 with a 4.38 ERA and 10 strikeouts in his career against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 81-69 on the year and play the Mariners, Athletics, and Angels next. The Houston Astros are batting .252 on the season, have a .318 OBP, and a .400 slugging percentage. The Houston Astros pitching staff has a 3.86 ERA and a 1.22 WHIP. Jose Altuve leads the Houston Astros with 146 hits and 70 RBI while Jeremy Pena and Christian Walker have combined for 271 hits and 137 RBI.

Jason Alexander gets the ball for the Houston Astros, and he is 4-1 with a 4.19 ERA and 55 strikeouts this season. This will be Alexander’s first career game against the Texas Rangers.

Texas Rangers @ Houston Astros Betting Trends: September 15, 2025

• Probable Starting Pitcher: Jason Alexander      Record this season: 4-1      ERA: 4.18
• Home Record: 0-1
• Last 5 against Rangers: –

Why the Houston Astros will win

• The Astros have won 13 of their last 14 games against AL West opponents following a road loss.
• The Rangers have lost each of their last four night games at Daikin Park after going to extra innings.
• The Astros have covered the run line in each of their last seven games following a loss.
• The Rangers have failed to cover the run line in four of their last five games after going to extra innings.
• The Astros have led after 3 innings in each of their last five night games.
• The Astros have led after 5 innings in each of their last five night games.

• Probable Starting Pitcher: Jack Leiter      Record this season: 9-8      ERA: 3.81
• Road Record: 3-6
• Last 5 against Astros: 1-0

Why the Texas Rangers will win

• The underdogs have won seven of the Rangers’ last eight games.
• The Astros have lost eight of their last 10 games as favorites against AL West opponents.
• The underdogs have covered the run line in each of the last seven games between the Rangers and Astros.
• The Astros have failed to cover the run line in eight of their last nine games as favorites against AL West opponents following a loss.
• The Rangers have led after 3 innings in four of their last five games against AL West opponents.
• The Rangers have led after 5 innings in seven of their last eight games against AL West opponents.

Total Runs Facts

• Each of the Astros’ last four games against American League opponents have gone UNDER the total runs line.
• Each of the Rangers’ last four road games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last 10 home games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Rangers’ last eight road games against AL West opponents.

Houston Astros Player Prop Facts

• Jake Meyers has hit a home run in each of his last two appearances with the Astros as home favorites against the Rangers.
• Yainer Diaz has recorded a Double in each of the Astros’ last three night games against opponents that held a winning record.
• Ramon Urias has recorded at least one hit in each of his last 10 appearances with his team as a favorite against AL West opponents.
• Jeremy Pena ranks 8th amongst qualified players for Batting Average (.297) this season.

Texas Rangers Player Prop Facts

• Josh Jung has recorded at least one hit in each of his last 17 appearances against AL West opponents.
• Corey Seager has hit a home run in three of his last four appearances against AL West opponents.
• Corey Seager has recorded a Double in three of his last four appearances with the Rangers as underdogs.

Matchup/League Facts

• The Astros rank 1st in the league for strikeouts this season (1404).
• The Astros rank 4th in the league for opponent batting average this season (.231).
• The Rangers rank 1st in the league for ERA this season (3.42).
• The Rangers rank 1st in the league for runs allowed this season (549).

Astros vs Rangers Prediction

The Rangers are hot and Leiter is starting to come into his own, so you can make a case for the road team here. However, Leiter does see his ERA jump to 4.45 on the road in 60.2 innings. Alexander has won each of his last 8 starts, and he’s allowed 9 hits and 3 runs in his last 12 innings. Alexander hasn’t been good in 30 home innings, but he’s finding ways to win overall lately, and the Astros are a tough out at home. The Astros also have a history of getting things done this time of year. I’ll side with the Astros and the reasonably cheap price.