Astros vs Rangers Prediction 9/17/25 MLB Picks Today

The Texas Rangers and Houston Astros meet Wednesday in MLB action at Daikin Park. Here’s a Astros vs Rangers Prediction. This article will include a Astros vs Rangers Pick.

Texas Rangers Betting Preview

The Texas Rangers are 79-73 on the year and play the Marlins, Twins, and Guardians next. The Texas Rangers are batting .238 on the season, have a .307 OBP, and a .388 slugging percentage. The Texas Rangers pitching staff has a 3.44 ERA and a 1.17 WHIP. Josh Smith leads the Texas Rangers with 123 hits and 34 RBI, while Wyatt Langford and Adolis Garcia have combined for 230 hits and 135 RBI.

Jacob deGrom gets the ball for the Texas Rangers, and he is 12-7 with a 2.82 ERA and 171 strikeouts this season. deGrom is 1-1 with a 2.33 ERA and 23 strikeouts in his career against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 83-69 on the year and play the Mariners, Athletics, and Angels next. The Houston Astros are batting .253 on the season, have a .318 OBP, and a .400 slugging percentage. The Houston Astros pitching staff has a 3.85 ERA and a 1.22 WHIP. Jose Altuve leads the Houston Astros with 147 hits and 72 RBI while Jeremy Pena and Christian Walker have combined for 276 hits and 139 RBI.

Cristian Javier gets the ball for the Houston Astros, and he is 1-3 with a 4.78 ERA and 26 strikeouts this season. Javier is 6-1 with a 3.71 ERA and 76 strikeouts in his career against the Texas Rangers.

Texas Rangers @ Houston Astros Betting Trends: September 17, 2025

• Probable Starting Pitcher: Cristian Javier      Record this season: 1-3      ERA: 4.78
• Home Record: 1-2
• Last 5 against Rangers: 2-1

Why the Houston Astros will win

• The Astros have won each of their last four games as home underdogs against AL West opponents.
• The Rangers have lost each of their last three games as favorites after playing the previous day.
• The Rangers have failed to cover the run line in each of their last seven games as favorites against the Astros following a road loss.
• The Astros have covered the run line each of their last six night games against teams that held a winning record.
• The Astros have led after 5 innings in each of their last seven night games.
• The Astros have led after 3 innings in each of their last seven night games.
• The Astros have won the first inning in three of their last four home games against AL West opponents that held a winning record.

• Probable Starting Pitcher: Jacob deGrom      Record this season: 12-7      ERA: 2.82
• Road Record: 6-2
• Last 5 against Astros: 1-1

Why the Texas Rangers will win

• The Astros have lost five of their last six games against American League opponents following a win.
• The Astros have failed to cover the run line in 10 of their last 12 games against American League opponents following a home win.
• The Rangers have covered the run line in nine of their last 10 Wednesday night games against American League opponents that held a winning record.
• The Rangers have led after 5 innings in five of their last six games as road favorites.
• The Rangers have led after 3 innings in six of their last eight games as favorites.

Total Runs Facts

• Each of the Astros’ last four home games have gone OVER the total runs line.
• Each of the Rangers’ last four road games against AL West opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Rangers’ last eight night games at Daikin Park.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last four games as home underdogs against AL West opponents.

Houston Astros Player Prop Facts

• Cristian Javier has recorded five or more strikeouts in four of his last five appearances with the Astros as home underdogs.
• Jose Altuve has recorded at least one hit in each of his last 10 appearances with the Astros as home underdogs against the Rangers.
• Isaac Paredes has hit a home run in four of his last seven home appearances against AL West opponents that held a winning record.
• Yainer Diaz has recorded a Double in four of his last five appearances with the Astros as underdogs.
• Jeremy Pena ranks 6th amongst qualified players for Batting Average (.304) this season.

Texas Rangers Player Prop Facts

• Jacob deGrom has recorded seven or more strikeouts in each of his last eight Wednesday appearances.
• Josh Jung has recorded at least one hit in each of his last 19 appearances against AL West opponents.
• Josh Jung has recorded at least one Double in each of the Rangers’ last three games as road favorites against AL West opponents.
• Corey Seager has hit a home run in three of his last four appearances against AL West opponents.
• Jacob deGrom ranks 9th amongst qualified players for Earned Run Average (2.82) this season.

Matchup/League Facts

• The Astros rank 1st in the league for strikeouts this season (1423).
• The Astros rank 4th in the league for opponent batting average this season (.232).
• The Rangers rank 1st in the league for ERA this season (3.44).
• The Rangers rank 1st in the league for runs allowed this season (561).

Astros vs Rangers Prediction

The Rangers need a bounce back win and deGrom continues to deal with his 2.82 ERA and 0.92 WHIP. Javier keeps having issues finding his form, and he’s allowed 12 hits and 8 runs in his last 10.1 innings. This is pretty much a must win for the Rangers if they’re going to stay in the wild card race. Can’t blow this game with their ace on the bump. I’ll roll with the more trustworthy pitcher in the Rangers.