Astros vs Rockies Prediction 4/16/26 MLB Picks Today
Colorado Rockies (6-12) vs. Houston Astros (8-11)
April 16, 2026 8:10 pm EDT
The Line: Houston Astros -194 / Colorado Rockies 159; Over/Under: 8.5
(Get latest betting odds)
The Colorado Rockies and Houston Astros meet Thursday in MLB action at Daikin Park. Here’s an Astros vs. Rockies Prediction. This article will include an Astros vs. Rockies Pick.
Colorado Rockies Betting Preview
The Colorado Rockies are 6-12 on the year and play the Padres and Dodgers next. The Colorado Rockies are batting .235 on the season and have a .303 OBP, and a .378 slugging percentage. The Colorado Rockies pitching staff has a 4.12 ERA and a 1.36 WHIP. TJ Rumfield leads the Colorado Rockies with 17 hits and 8 RBI while Ezequiel Tovar and Hunter Goodman have combined for 32 hits and 13 RBI.
Tomoyuki Sugano gets the ball for the Colorado Rockies, and he is 1-0 with a 2.16 ERA and 12 strikeouts this season. This will be Sugano’s first career game against the Houston Astros.
Houston Astros Betting Preview
The Houston Astros are 8-11 on the year and play the Guardians and Cardinals next. The Houston Astros are batting .269 on the season and have a .359 OBP, and a .440 slugging percentage. The Houston Astros pitching staff has a 6.17 ERA and a 1.67 WHIP. Yordan Alvarez leads the Houston Astros with 21 hits and 17 RBI, while Jose Altuve and Christian Walker have combined for 39 hits and 22 RBI.
Ryan Weiss gets the ball for the Houston Astros, and he is 0-2 with a 7.36 ERA and 15 strikeouts this season. This will be Weiss’ second career game against the Colorado Rockies.
Why the Houston Astros will win
- The home team has won each of the Astros’ last 10 games.
- The Rockies have lost each of their last 13 road games against teams that held a losing record.
- The Astros have covered the run line in each of their last six night games against National League opponents following a win.
- The Rockies have failed to cover the run line in each of their last five games after playing the previous day.
- The Rockies have trailed after 5 innings in each of their last 13 road games against opponents that held a losing record.
- The Astros have won the first inning in four of their last five home games.
- The Rockies have trailed after 3 innings in eight of their last nine road games against opponents that held a losing record.
Why the Colorado Rockies will win
- The Astros have lost five of their last seven games as favorites.
- The Rockies have won four of their last six games as underdogs against American League opponents.
- The Astros have failed to cover the run line in each of their last seven Thursday home games.
- The Rockies have covered the run line in five of their last six games against the Astros.
- The Astros have lost the first inning in six of their last seven games.
- The Rockies have led after 3 innings in each of their last five Thursday games against AL West opponents that held a losing record.
Total Runs Facts
- Six of the Astros’ last seven home games have gone OVER the total runs line.
- Eighteen of the Rockies’ last 23 games as underdogs against the Astros have gone UNDER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last seven games.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rockies’ last four games.
Houston Astros Player Prop Facts
- Christian Walker has recorded at least one hit in 25 of his last 26 appearances against the Rockies after playing the previous day.
- Yordan Alvarez has hit a home run in three of the Astros’ last four night games.
Colorado Rockies Player Prop Facts
- Willi Castro has recorded at least one hit in each of his last 10 appearances against the Astros after playing the previous day.
- Kris Bryant has hit a home run in four of his last six appearances against the Astros.
Matchup/League Facts
- The Astros rank 1st in the league for doubles this season (48).
- The Astros rank 30th in the league for ERA this season (6.17).
- The Rockies rank 30th in the league for strikeouts against this season (189).
- The Rockies rank 29th in the league for strikeouts this season (127).
Astros vs Rockies Prediction
If the Rockies weren’t the Rockies, I’d take a stab at the big plus money. Weiss isn’t off to a great career with his 7.36 ERA and 2.09 WHIP through 11 innings. The Rockies saw Weiss at Coors and tagged him for eight hits and six earned runs in 2.2 frames. No, thanks. With that said, Mejia has a 5.40 ERA and 1.80 WHIP through 8.1 innings. Both pitchers have also had issues with control and have walked a combined 10 batters. I’m going to side with the over in this spot. I can’t get behind either of these pitchers right now.