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Athletics vs Orioles Prediction 6/6/25 MLB Picks Today

Baltimore Orioles (25-36) vs. Oakland Athletics (24-40)
June 6, 2025 10:05 pm EDT
The Line: Oakland Athletics 105 / Baltimore Orioles -125; Over/Under: 11
(Get latest betting odds)

In this article, we will formulate an Athletics vs Orioles prediction for this MLB game on Friday, June 6, at Sutter Health Park in Sacramento, California. Let’s take a look at the prediction for this MLB matchup.

Baltimore Orioles Betting Preview

The Baltimore Orioles (25-36, 13-19 Away) are playing their best baseball of the season after winning nine of the previous 11 games. The Orioles are currently on a six-game winning streak after recording back-to-back sweeps of the White Sox and Mariners. In Game 3, a 4-3 victory in Seattle, Adley Rutschman led the team with two RBI, while Zach Eflin got the win after allowing three runs on eight hits with seven strikeouts and no walks across 6.0 innings of work.

This season, the Orioles average 3.84 runs per game (25th in the MLB) on a .237/.302/.386 triple-slash. When it comes to pitching, the Orioles’ staff has a 5.10 ERA (28th) and 1.43 WHIP (27th). Cedric Mullins leads the Orioles with a .232 batting average, ten home runs, and 31 RBI this season.

Dean Kremer will take the mound for the Orioles on Friday. The 29-year-old right-hander has a 5-5 record in 12 starts this year with a 4.70 ERA and 1.39 WHIP in 67.0 innings.

Athletics Betting Preview

The Athletics (24-40, 10-22 Home) snapped their nine-game losing skid with a 14-3 win over the Minnesota Twins, scoring a season-high 14 runs in the process. Despite that big W, the A’s did lose the series and were swept by the Astros and Blue Jays before. Tyler Soderstrom had a game of his career as he blasted his first-ever grand slam and led the offense with a career-high six RBI. Mitch Spence got the win after allowing one run on three hits with four strikeouts and one walk in 5.0 innings.

This year, the Athletics average 4.30 runs per game (15th in the MLB) on a .256/.323/.421 triple-slash. When it comes to pitching, the Athletics’ staff has a 5.79 ERA (30th) and 1.54 WHIP (29th). Tyler Soderstrom leads the Athletics with a .257 batting average, 14 home runs, and 42 RBI this season.

The projected starting pitcher for the Athletics is JP Sears, who is 4-5 in 12 starts this season, with a 5.05 ERA and 1.18 WHIP in 62.1 innings.

Total Runs Facts

  • Each of the Athletics’ last nine games as underdogs against AL East opponents have gone OVER the total runs line.
  • Nine of the Orioles’ last 10 night games against American League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Athletics’ last eight Friday night games against American League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Orioles’ last five games as favorites.

Matchup/League Facts

  • The Athletics rank 30th in the league for runs allowed this season (392).
  • The Athletics rank 29th in the league for walks allowed this season (255).
  • The Orioles rank 28th in the league for hits allowed this season (562).
  • The Orioles rank 27th in the league for opponent batting average this season (.269).

Athletics vs Orioles Prediction

The Orioles won seven of the previous ten H2H encounters, but the teams have traded victories in the last six meetings. Seven of the last ten H2Hs went Over, and given how both teams play defense this season, I expect another high-scoring affair on Friday. Eight of the A’s previous ten games went Over, and given that Kremer and Sears are starting on the mound, I am going with another Over.

Oliver Zivic's Free Pick: Over 10.5

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Oliver Zivic

Professional journalist and expert bettor with 20+ years of experience. I cover Football (soccer), NFL, NBA, NHL, MLB, CFB, and CBB.

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