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Athletics vs Padres Prediction 4/8/25 MLB Picks Today

San Diego Padres (9-2) vs. Oakland Athletics (4-7)
April 8, 2025 10:05 pm EDT
The Line: Oakland Athletics 124 / San Diego Padres -148; Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate an Athletics vs Padres prediction for this MLB game on Tuesday, April 8, at Sutter Health Park in Sacramento, California. Let’s take a look at the prediction for this MLB matchup.

San Diego Padres Betting Preview

The San Diego Padres (9-2, 2-2 Away) opened the new season with seven consecutive wins and a series sweep over the Atlanta Braves and Cleveland Guardians. The Padres lost two of three games to the Chicago Cubs but defeated the Athletics 5-4 in Game 1 of the current series. Manny Machado and Jake Cronenworth contributed with two RBI apiece, while Michael King got a win after allowing three runs on eight hits with two strikeouts and two walks in 5.2 innings.

This year, the Padres average 4.64 runs per game (12th in the MLB) on a .282/.351/.422 triple-slash. When it comes to pitching, the Padres’ staff has a 2.88 ERA (4th) and 1.15 WHIP (8th). Jackson Merrill leads the Padres with a .378 batting average, three home runs, and ten RBI this season.

Dylan Cease will take the mound for the Padres on Tuesday. The 29-year-old right-hander has a 1-0 record in two starts this year with a 3.38 ERA and 1.03 WHIP over 10.2 innings of work.

Athletics Betting Preview

The Athletics (4-7, 0-4 Home) are still looking for the first home win of the year after losing the previous four. The A’s split the series with the Mariners, suffered a series sweep to the Cubs, and won two of three games against the Rockies in Denver. They trailed from the first inning in Game 1 against the Padres and lost 5-4 in the end. Tyler Soderstrom blasted a couple of solo homers to lead his team on offense. Luis Severino took a loss after allowing five runs on eight hits with three strikeouts and no walks over 7.0 innings of work.

This season, the Athletics average 4.09 runs per game (14th in the MLB) on a .242/.308/.416 slash line. Regarding pitching, the A’s staff has a 5.60 ERA (28th) and 1.56 WHIP (29th). Tyler Soderstrom leads the Athletics with a .381 batting average, six home runs, and ten RBI this season.

The projected starting pitcher for the Athletics is Jeffrey Springs, who has a 1-1 record in two starts this year with a 4.00 ERA and 1.44 WHIP in 9.0 innings.

Why the Padres will beat the Athletics

  • The Padres have won each of their last eight games against American League opponents.
  • The Athletics have lost nine of their last 10 home games after playing the previous day.
  • The Padres have covered the run line in six of their last seven road games against the Athletics.
  • The Athletics have failed to cover the run line in five of their last six home games.
  • The Athletics have trailed after 5 innings in each of their last 11 Tuesday night games against NL West opponents that held a winning record.
  • The Padres have won the first inning in three of their last four road games against American League opponents that held a losing record.
  • The Padres have led after 3 innings in five of their last six games as favorites.

Total Runs Facts

  • Each of the Athletics’ last six games as underdogs against National League opponents have gone OVER the total runs line.
  • Each of the Padres’ last three games have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Athletics’ last eight night games against National League opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Padres’ last 10 games as favorites.

Matchup/League Facts

  • The Athletics rank 3rd in the league for home runs this season (18).
  • The Athletics rank 28th in the league for ERA this season (5.60).
  • The Padres rank 3rd in the league for steals this season (18).
  • The Padres rank T3rd in the league for strikeouts against this season (68).

Athletics vs Padres Prediction

The Padres won eight of the previous ten H2H encounters, including the last seven, while they scored 4+ runs in each of those ten duels. Dylan Cease secured a W in his previous start against the A’s as he posted a 1.50 ERA in 6.0 innings. Not only do the Padres have a better offense, but they also have a stronger bullpen, and I am backing them to take a 2-0 lead in the series with a win on Tuesday.


Oliver Zivic

Professional journalist and expert bettor with 20+ years of experience. I cover Football (soccer), NFL, NBA, NHL, MLB, CFB, and CBB.

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