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Athletics vs Pirates Prediction 9/20/25 MLB Picks Today

Athletics vs Pirates
September 20, 2025 6:40 pm EDT
The Line: Pirates -110 / Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate an Athletics vs Pirates Prediction for this MLB game on Saturday, September 20th at the PNC Park in the second game of this series, with the Athletics having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 65-89 record this season and are sitting on the last place of the NL Central. They have a 42-37 home record, and are 61-88 in over/under. They are coming off a 3-4 home defeat by the A’s, and are 1-11 in their last 12 games. Under is 8-3 in their last 11 games are playing the Reds and the Braves next.

The Pirates have a .230 batting average this season, .305 OBP and .347 slugging percentage. Pittsburgh’s pitching staff has a 3.88 ERA and 1.23 WHIP. Bryan Reynolds leads the Pirates with 136 hits, and a team-high 72 RBI. He is also the team’s best hitter with a .243 batting average, while Oneil Cruz leads the team in home runs, with 19.

Bubba Chandler (R) is the projected starting pitcher for the Pirates, and he has a 2-1 record, 5.66 ERA and 1.16 WHIP.

Athletics Preview

The Athletics have a 73-81 record this season and are sitting on the last place of the AL West. The Athletics have a 40-39 road record and are 75-72 in over/under. They are coming off a 4-3 road victory over the Pirates, and have four straight wins. Under is 8-3 in their last 11 games and are playing the Astros and the Royals next.

The Athletics have a .254 batting average this season, .320 OBP and .435 Slugging percentage. Athleticspitching staff has a 4.69 ERA and 1.36 WHIP. Brent Rooker leads the Athletics with 160 hits, while Jacob Wilson is the team’s best hitter with a .317 batting average. Tyler Soderstrom adds a team-high 90 RBI, while Nick Kurtz adds a team-high 33 home runs.

Luis Morales (R) is the projected starter for the Athletics, and he has a 4-1 record, 3.08 ERA, and 1.11 WHIP.

Athletics @ Pittsburgh Pirates Betting Trends: September 20, 2025

 

  • Probable Starting Pitcher: Bubba Chandler      Record this season: 2-1      ERA: 5.66
  • Home Record: 1-1
  • Last 5 against Athletics: –

Why the Pittsburgh Pirates will win

  • The Athletics have lost four of their last five games as road favorites against NL Central opponents.
  • The underdogs have won 10 of the last 13 games between the Athletics and Pirates.
  • The Pirates have covered the run line in each of their last 10 games as home underdogs against AL West opponents following a loss.
  • The Athletics have failed to cover the run line in eight of their last nine road games against National League opponents following a win.
  • The Athletics have trailed after 3 innings in four of their last five games.
  • The Athletics have lost the first inning in three of their last four games as favorites.
  • The Pirates have led after 5 innings in three of their last four home games against opponents that held a losing record.

 

  • Probable Starting Pitcher: Luis Morales      Record this season: 4-1      ERA: 3.08
  • Road Record: 1-0
  • Last 5 against Pirates: –

Why the Athletics will win

  • The Pirates have lost each of their last 11 night games against American League opponents that held a losing record.
  • The Athletics have won each of their last six games against the Pirates.
  • The Athletics have covered the run line in each of their last 10 Saturday night road games.
  • The Pirates have failed to cover the run line in each of their last six home games after playing the previous day.
  • The Pirates have trailed after 3 innings in four of their last five home games against AL West opponents that held a losing record.
  • The Athletics have led after 5 innings in each of their last five games against the Pirates.

Total Runs Facts

  • Each of the Athletics’ last seven games as favorites have gone UNDER the total runs line.
  • Seven of the Pirates’ last eight games against American League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last seven night games between the Athletics and Pirates.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Athletics’ last five night games at PNC Park.

Pittsburgh Pirates Player Prop Facts

  • Jared Triolo has hit a home run in two of the Pirates’ last three home games against opponents that held a losing record.
  • Bryan Reynolds has recorded a Double in each of the Pirates’ last five games as home underdogs against AL opponents.
  • Tommy Pham has recorded at least one hit in seven of his last eight home appearances against opponents that held a losing record.
  • Oneil Cruz ranks 4th in the league in Steals (38) this season.

Athletics Player Prop Facts

  • Nick Kurtz has hit a home run in four of the Athletics’ last five games against NL opponents.
  • JJ Bleday has recorded at least one hit in each of his last eight appearances in night games against NL Central teams that held a losing record.
  • Jacob Wilson ranks 2nd amongst qualified players for Batting Average (.317) this season.

Matchup/League Facts

  • The Pirates rank 30th in the league for runs scored this season (548).
  • The Pirates rank 30th in the league for home runs this season (108).
  • The Athletics rank T2nd in the league for doubles this season (279).
  • The Athletics rank 29th in the league for home runs allowed this season (213).

Athletics vs Pirates Prediction

The A’s have won their last 6 meetings against the Pirates, and both teams are tied 3-3 wins in their last 6 meetings in Pittsburgh. Under is 6-2-3 in their last 11 meetings.

In this Athletics vs Pirates Prediction, both teams are coming at a pickem price. The Pirates are on a free fall in the final stretch of the season, and I certainly don’t trust Bubba Chandler to be the guy breaking their losing streak. The A’s have 4 consecutive wins, and they are putting Morales on the mound, who has been excellent on the road, with a 1.88 ERA in his three road starts. They also have a better offense to offer him run support, so I like them to get away with the road win in this one.

Nikos Lagouretos's Free Pick: Athletics ML

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