Athletics vs Red Sox Prediction 9/10/25 MLB Picks Today

The Boston Red Sox and Athletics meet Wednesday in MLB action at Sutter Health Park. Here’s a Athletics vs Red Sox Prediction. This article will include a Athletics vs Red Sox Pick.

Boston Red Sox Betting Preview

The Boston Red Sox are 81-65 on the year and play the Yankees, Athletics, and Rays next. The Boston Red Sox are batting .254 on the season, have a .324 OBP, and a .425 slugging percentage. The Boston Red Sox pitching staff has a 3.73 ERA and a 1.29 WHIP. Jarren Duran leads the Boston Red Sox with 145 hits and 78 RBI, while Trevor Story and Ceddanne Rafaela have combined for 263 hits and 150 RBI.

Payton Tolle gets the ball for the Boston Red Sox, and he is 0-1 with a 7.56 ERA and 10 strikeouts this season. This will be Tolle’s first career game against the Athletics.

Athletics Betting Preview

The Athletics are 66-80 on the year and play the Reds, Red Sox, and Pirates next. The Athletics are batting .254 on the season, have a .320 OBP, and a .433 slugging percentage. The Athletics pitching staff has a 4.81 ERA and a 1.36 WHIP. Brent Rooker leads the Athletics with 151 hits and 82 RBI while Tyler Soderstrom and Jacob Wilson have combined for 281 hits and 142 RBI.

Mason Barnett gets the ball for the Athletics, and he is 1-1 with a 9.00 ERA and 9 strikeouts this season. This will be Barnett’s first career game against the Boston Red Sox.

Boston Red Sox @ Athletics Betting Trends: September 10, 2025

• Probable Starting Pitcher: Mason Barnett      Record this season: 1-1      ERA: 9.00
• Home Record: 0-1
• Last 5 against Red Sox: –

Why the Athletics will win

• The underdogs have won seven of the Athletics’ last eight games.
• The Red Sox have lost three of their last four games as favorites.
• The underdogs have covered the run line in seven of the Athletics’ last eight games.
• The Red Sox have failed to cover the run line in four of their last five games as road favorites.
• The Red Sox have trailed after 3 innings in three of their last four games as favorites.
• The Athletics have led after 5 innings in four of their last five day games against AL East opponents that held a winning record.

• Probable Starting Pitcher: Payton Tolle      Record this season: 0-1      ERA: 7.56
• Road Record: 0-1
• Last 5 against Athletics: –

Why the Boston Red Sox will win

• The Red Sox have won each of their last eight road games against American League opponents that held a losing record.
• The Athletics have lost each of their last five home games.
• The Athletics have failed to cover the run line in each of their last five home games.
• The Red Sox have covered the run line in each of their last five day games against AL West opponents following a win.
• The Red Sox have won the first inning in each of their last four road games against American League opponents.
• The Athletics have trailed after 3 innings in each of their last four home games.
• The Athletics have trailed after 5 innings in each of their last five home games.

Total Runs Facts

• Each of the Red Sox’s last six road games against American League opponents have gone UNDER the total runs line.
• Each of the last four games between the Red Sox and Athletics have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Athletics’ last six games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last four road games against American League opponents.

Athletics Player Prop Facts

• Jacob Wilson ranks 2nd amongst qualified players for Batting Average (.319) this season.

Matchup/League Facts

• The Athletics rank 2nd in the league for doubles this season (267).
• The Athletics rank 29th in the league for home runs allowed this season (205).
• The Red Sox rank 1st in the league for doubles this season (295).
• The Red Sox rank 28th in the league for strikeouts against this season (1286).

Athletics vs Red Sox Prediction

I’m not running to the window to back either of these rookie pitchers, who haven’t shown us much up to this point. Tolle has been awful in 8.1 innings, allowing 8 hits and 7 runs while walking 6. Barnett has allowed 11 hits and 9 runs in 9 innings. Yuck. You should probably consider the over if this is an indication of things to come. Overall, I’ll give the Red Sox the edge because they’re the better team and are still playing for something. The Red Sox should find a way to win regardless of a rough pitching matchup.