Athletics vs St. Louis Cardinals Prediction 5/12/26 MLB Picks Today

The St. Louis Cardinals and the Athletics meet Tuesday in MLB action from Sutter Health Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a St. Louis Cardinals vs. Athletics prediction.

Starting Pitching Matchup

The St. Louis Cardinals will send out Andre Pallante for the start and Pallante is 3-3 with a 4.34 ERA and 29 strikeouts this season. This will be Pallante’s first career start against the Athletics. The Athletics will send out Jeffrey Springs here and Springs is 3-2 with a 3.89 ERA and 39 strikeouts this season. In his career, Springs is 0-2 with a 3.18 ERA and 12 strikeouts against the Cardinals.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to bounce back from a 3-2 loss at the hands of the Padres last time out to sit at 23-17 this season. After this series, the Cardinals will head home for a series against the Kansas City Royals.

Cardinals Drop Back-To-Back Games

Jordan Walker leads the Cardinals with 44 hits, 8 doubles, 11 home runs and 29 RBIs while Alec Burleson has 41 hits with 10 doubles, 6 home runs and 30 RBIs. JJ Wetherholt has 36 hits with 7 home runs and 20 RBIs while Ivan Herrera has 38 hits with 11 doubles, 4 home runs and 18 RBIs. Nolan Gorman has 29 hits with 5 home runs and 22 RBIs this season. Masyn Winn’s added 33 hits with 6 doubles and 16 RBIs and Nathan Church has 29 hits with 5 home runs and 17 RBIs this season.

Athletics Recap

The Athletics come into this game looking to bounce back from a 2-1 loss at the hands of the Orioles last time out to slide to 21-19 this season. After this series, the Athletics will take on the San Francisco Giants in a series at home.

Athletics Have Three-Game Win Streak Snapped

Shea Langeliers has 50 hits with 9 doubles, 11 home runs and 22 RBIs while Tyler Soderstrom’s added 30 hits with 12 doubles, a triple, 5 home runs and 20 RBIs. Brent Rooker has 17 hits with 5 home runs and 18 RBIs while Max Muncy has also chipped in 22 hits with 5 doubles, 2 triples, 2 home runs and 7 RBIs this season. Jacob Wilson also has 47 hits with 8 doubles, 3 home runs and 19 RBIs and Nick Kurtz has 37 hits with 7 doubles, 5 home runs and 20 RBIs this season.

St. Louis Cardinals @ Athletics Betting Trends: May 12, 2026

• Probable Starting Pitcher: Jeffrey Springs      Record this season: 3-2      ERA: 3.89
• Home Record: 2-1
• Last 5 against Cardinals: 0-2

Why the Athletics will win

• The Cardinals have lost eight of their last nine night games against AL West opponents that held a winning record.
• The Athletics have won six of their last seven games following a road loss.
• The Cardinals have failed to cover the run line in eight of their last nine night games against AL West opponents that held a winning record.
• The Athletics have covered the run line in each of their last four games.
• The Athletics have led after 5 innings in five of their last six games against National League opponents.
• The Athletics have led after 3 innings in each of their last four games against opponents that held a winning record.
• The Athletics have won the first inning in four of their last five games against opponents that held a winning record.

• Probable Starting Pitcher: Andre Pallante      Record this season: 3-3      ERA: 4.34
• Road Record: 2-0
• Last 5 against Athletics: –

Why the St. Louis Cardinals will win

• The Cardinals have won each of their last nine night games against teams that held a winning record.
• The Athletics have lost six of their last nine games as favorites against National League opponents.
• The Cardinals have covered the run line each of their last nine night games against teams that held a winning record.
• The Athletics have failed to cover the run line in seven of their last eight games as home favorites against National League opponents following a loss.
• The Athletics have trailed after 3 innings in each of their last four games against NL Central opponents.
• The Athletics have lost the first inning in three of their last four games against NL Central opponents.
• The Cardinals have led after 5 innings in each of their last four road games against American League opponents.

Total Runs Facts

• Each of the Athletics’ last seven games as favorites against National League opponents have gone UNDER the total runs line.
• Each of the Cardinals’ last four games have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 11 of the Athletics’ last 12 games as home favorites.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Cardinals’ last five night games against American League opponents.

Athletics Player Prop Facts

• Brent Rooker has hit a home run in four of the Athletics’ last five home games against NL Central opponents.
• Zack Gelof has recorded at least one hit in each of his last nine appearances.
• Shea Langeliers ranks 2nd in the league in Hits (50) this season.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in three of the Cardinals’ last five road games against AL opponents that held a winning record.
• Lars Nootbaar has recorded at least one hit in each of his last seven appearances in night games against teams that held a winning record.
• Jordan Walker ranks T8th in the league in Home Runs (11) this season.

Matchup/League Facts

• The Athletics rank 26th in the league for walks allowed this season (174).
• The Athletics rank 6th in the league for slugging percentage this season (.400).
• The Cardinals rank 30th in the league for strikeouts this season (291).
• The Cardinals rank T27th in the league for triples this season (2).

St. Louis Cardinals vs. Athletics Prediction

I’m on the Athletics here. I get that the Cardinals have been on quite the roll, but their numbers against lefties aren’t as strong and Pallante’s in a rough spot here having to face a hard hitting Athletics lineup in this hitter’s haven in Sacramento. Springs hasn’t been at his best at home but I think he’s good enough for the win here. Give me the Athletics.