Orioles vs Astros Prediction 8/24/25 MLB Picks Today

The Houston Astros and the Baltimore Orioles meet Sunday in MLB action from Camden Yards. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Orioles vs Astros Prediction.

Starting Pitching Matchup

The Houston Astros will start Spencer Arrighetti here and Arrighetti is 1-4 with a 6.94 ERA and 21 strikeouts this season. This will be Arrighetti’s second career start against the Orioles. Trevor Rogers will get the start for the Orioles here and is 6-2 with a 1.41 ERA and 67 strikeouts this season. This will be Rogers’ second career start against the Astros.

Houston Astros Recap

The Houston Astros come into this game looking to add on to their 9-8 win over the Baltimore Orioles last time out to sit at 72-58 this season. After this series, the Astros will head home for a series against the Colorado Rockies.

Astros Win Three In A Row

Jose Altuve has 132 hits including 19 doubles, 22 home runs and 64 RBIs. Jeremy Pena also has 119 hits with 22 doubles, 14 homers and 49 RBIs with 17 stolen bases as well. Jake Meyers has 15 doubles as well and Christian Walker has 18 home runs and 70 RBIs but has also accrued a team-high 137 strikeouts so far this season. Altuve also has 9 stolen bases while Jake Meyers has 14 stolen bases this season. Isaac Paredes also has 19 home runs with 50 RBIs of his own and Cam Smith has contributed 7 homers and 48 RBIs.

Why the Houston Astros will win

• The Astros have won nine of their last 10 games as underdogs against the Orioles.
• The Orioles have lost seven of their last eight games as favorites against the Astros following a loss.
• The Astros have covered the run line in each of their last 10 games as underdogs against the Orioles.
• The Orioles have failed to cover the run line in each of their last six games as home favorites against AL West opponents.

Houston Astros Player Prop Facts

• Christian Walker has hit a home run in each of the Astros’ last four road games against opponents that held a losing record.
• Jake Meyers has recorded at least one hit in each of his last 16 road appearances against AL opponents.
• Isaac Paredes has recorded at least one Double in three of his last four appearances in day games.
• Jeremy Pena ranks 3rd amongst qualified players for Batting Average (.307) this season.

Baltimore Orioles Recap

The Baltimore Orioles come into this game looking to bounce back from their loss at the hands of the Astros on Saturday to sit at 59-70 this season. After this series, the Orioles will welcome the Boston Red Sox to town for a division series.

Orioles Lose Three Straight, Looking To Avoid Sweep

Adley Rutschman has 70 hits with 16 doubles, 9 homers and 29 RBIs. Jackson Holliday has 118 hits with 17 doubles, 2 triples, 15 homers and 49 RBIs. Gunnar Henderson has 128 hits with 29 doubles, 5 triples, 15 home runs and 57 RBIs with 16 stolen bases and 112 strikeouts while Holliday has a team-high 116 strikeouts as well this season. Heston Kjerstad’s added 4 homers and 19 RBIs while Jordan Westburg has 15 home runs and 34 RBIs this season.

Why the Baltimore Orioles will win

• The Astros have lost six of their last seven day games against American League opponents.
• The Orioles have won four of their last five day games against American League opponents following a loss.
• The Astros have failed to cover the run line in seven of their last eight day games against AL East opponents.
• The Orioles have covered the run line in six of their last seven day games against American League opponents that held a winning record.

Baltimore Orioles Player Prop Facts

• Trevor Rogers has recorded five or more strikeouts in eight of his last nine appearances.
• Colton Cowser has recorded at least one hit in each of his last 12 appearances against AL West opponents.
• Tyler O’Neill has hit a home run in four of his last five appearances with the Orioles as favorites.

Total Runs Facts

• Seven of the Astros’ last eight games have gone OVER the total runs line.
• Each of the Orioles’ last five games against AL West opponents have gone OVER the total runs line.

Orioles vs Astros Prediction

I’m backing the Orioles here. I know the Astros have been every bit the better team in this series so far, but the thing here is that the Orioles have a clear edge in pitching here. You could easily argue that they haven’t had in the series to this point. Houston’s come out for some revenge after being beat up by Baltimore in the series between these two teams last week, but I think the Orioles salvage something here. Give me the Orioles in this one.