Blue Jays vs Astros Prediction Prediction 8/4/26 MLB Picks Today

In this article, we will formulate a Blue Jays vs Astros Prediction for this MLB matchup on Tuesday, August 4^th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Houston Astros Preview

The Houston Astros have a 58-56 record this season and are sitting in the 1st place of the AL West. They have a 29-28 home record and are coming off a 1-3 home loss against the Blue Jays. They will face the Padres and the Giants next.

The Houston Astros have a .246 batting average this season, .321 OBP and .416 Slugging percentage. Houston’s pitching staff has a 4.63 ERA and 1.38 WHIP. Yordan Alvarez is the team’s best hitter with a .330 batting average, leading the team in RBI with 84 and adding a team-high 35 home runs.

Hayden Wesneski (R) is the projected starting pitcher for the Houston Astros, and he has a 1-0 record, 4.76 ERA and 1.59 WHIP.

Toronto Blue Jays Preview

The Toronto Blue Jays have a 53-60 record this season and are sitting in the 5th place of the AL East. They have a 25-29 away record and are coming off a 3-1 road win against the Astros. They will face the Phillies and the Red Sox next.

The Toronto Blue Jays have a .243 batting average this season, .304 OBP and .378 Slugging percentage. Toronto’s pitching staff has a 4.04 ERA and 1.31 WHIP. Ernie Clement is the team’s best hitter with a .288 batting average. Kazuma Okamoto leads the team in RBI with 69 and adds a team-high 24 home runs.

Trey Yesavage (R) is the projected starting pitcher for the Toronto Blue Jays, and he has a 5-5 record, 3.73 ERA and 1.16 WHIP.

Toronto Blue Jays @ Houston Astros Betting Trends: August 4, 2026

• Probable Starting Pitcher: Hayden Wesneski       Record this season: 1-0      ERA: 4.76
• Home Record: 0-0
• Last 5 against Blue Jays: 0-0

Why the Houston Astros will win

• The Astros have won each of their last seven games against the Blue Jays following a home loss.
• The Blue Jays have lost each of their last four road games following a win.
• The Astros have covered the run line in each of their last seven games against the Blue Jays following a loss.
• The Blue Jays have failed to cover the run line in each of their last four games as underdogs following a win.
• The Astros have led after 3 innings in six of their last seven home games.
• The Blue Jays have trailed after 5 innings in seven of their last eight games at Daikin Park.

• Probable Starting Pitcher: Trey Yesavage      Record this season: 5-5      ERA: 3.73
• Road Record: 2-2
• Last 5 against Astros: 0-0

Why the Toronto Blue Jays will win

• The underdogs have won each of the last three games between the Blue Jays and Astros.
• The Astros have lost each of their last three games as favorites against AL East opponents.
• The Blue Jays have covered the run line in eight of their last nine night games against American League opponents following a road win.
• The Astros have failed to cover the run line in each of their last four games against AL East opponents.
• The Blue Jays have led after 3 innings in five of their last six night games against AL West opponents that held a winning record.
• The Blue Jays have led after 5 innings in five of their last six night games against AL West opponents that held a winning record.

Total Runs Facts

• Each of the last six games between the Blue Jays and Astros at Daikin Park have gone UNDER the total runs line.
• Eight of the Blue Jays’ last nine games have gone UNDER the total runs line.
• There has been no run scored during the first inning in each of the Astros’ last six home games against American League opponents.
• There has been no run scored during the first inning in each of the Blue Jays’ last six road games against AL West opponents.

Houston Astros Player Prop Facts

• Jeremy Pena has hit a home run in four of the Astros’ last six games as home favorites.
• Hayden Wesneski has recorded a win in three of his last four appearances with his team as a favorite against AL opponents .
• Hayden Wesneski has recorded four or more strikeouts in four of his last five home appearances.
• Jeremy Pena has recorded at least one hit in each of his last 18 appearances in night games.
• Yordan Alvarez ranks 1st in the league in Home Runs (35) this season.

Toronto Blue Jays Player Prop Facts

• Trey Yesavage has recorded a win in three of his last four appearances in night games against AL teams that held a winning record.
• Trey Yesavage has recorded six or more strikeouts in each of his six previous appearances with the Blue Jays as underdogs against AL opponents.
• Jesus Sanchez has recorded at least one hit in each of his last 10 road appearances against AL opponents.
• Alejandro Kirk has hit a home run in three of his last five appearances with the Blue Jays as underdogs against AL West opponents.
• Ernie Clement ranks T9th in the league in Hits (122) this season.

Matchup/League Facts

• The Astros rank 30th in the league for walks allowed this season (480).
• The Astros rank 29th in the league for steals this season (37).
• The Blue Jays rank 30th in the league for runs scored this season (442).
• The Blue Jays rank 30th in the league for triples this season (6).

Blue Jays vs Astros Prediction

Both teams are tied 4-4 in their last 8 meetings but the Astros are 3-1 in their last 4 meetings in Houston.

In this Blue Jays vs Astros Prediction, the Astros are coming as -130 home favorites. The Astros were red-hot prior to yesterday’s loss and I don’t trust them with Hayden Wesneski going up against Trey Yesavage, who has been better on the road with a 3.60 ERA. The Blue Jays also have a better bullpen to relief him and I like them as road dogs in this spot. Take the Jays on the moneyline.