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Blue Jays vs Rays Prediction 7/22/26 MLB Picks Today

Tampa Bay Rays (58-42) vs. Toronto Blue Jays (46-55)
July 22, 2026 7:07 pm EDT
The Line: Toronto Blue Jays -110 / Tampa Bay Rays -110; Over/Under: 8.5
(Get latest betting odds)

In this article we will formulate a Blue Jays vs Rays prediction for this MLB game on Wednesday, July 22nd at the Rogers Centre in Toronto, Ontario. Let’s take a look at the prediction for this MLB matchup. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 46-55 this year after they lost the first two games in this series by scores of 1-7 and 2-12. In game two, Toronto allowed the first eight runs and never had a chance in the lopsided loss. The Blue Jays recorded seven hits and they committed two errors in the game, while they were led by Varsho, who went 1-4 with one RBI. Gausman allowed nine hits and four earned runs over 3.1 innings for the loss, while Estrada allowed three earned runs in relief. Prior to this series, Toronto lost two out of three against the White Sox and two out of three against the Padres. 

This season, Toronto has a 4.21 ERA with a 1.32 WHIP and a .243 opponent batting average, while they have scored 400 runs with a .242 batting average and a .304 on base percentage. Kazuma Okamoto has led the Blue Jays with 22 home runs and 62 RBIs, while Andres Gimenez has added seven home runs and 38 RBIs. The projected starting pitcher for Toronto is Braydon Fisher, who is 3-3 with a 3.65 ERA and a 1.18 WHIP over 49.1 innings pitched this year. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 58-42 this season after they won game two by a score of 12-2 last night. Tampa Bay took the lead in the first inning and cruised to the win, but did allow two runs in the sixth to lose the shutout. The Rays recorded 21 hits in the game and they were led by Fortes, who went 3-5 with one home run and four RBIs. Rasmussen allowed seven hits and two earned runs over 5.0 innings for the win, while Sulser threw two innings in relief. Prior to this series, Tampa Bay lost all four against the Red Sox, but did win two out of three against the Mariners before that. 

This season, Tampa Bay has a 3.86 ERA with a 1.18 WHIP and a .234 opponent batting average, while they have scored 454 runs with a .261 batting average and a .334 on base percentage. Jonathan Aranda has led the Rays with 14 home runs and 65 RBIs, while Junior Caminero has added 29 home runs and 62 RBIs. The projected starting pitcher for Tampa Bay is Griffin Jax, who is 5-7 with a 4.08 ERA and a 1.27 WHIP over 75.0 innings pitched this season. 

Why the Toronto Blue Jays will win

  • The Rays have lost each of their last eight Wednesday games at Rogers Centre.
  • The Blue Jays have won seven of their last eight Wednesday home games against AL East opponents.
  • The Rays have failed to cover the run line in each of their last six Wednesday games at Rogers Centre.
  • The Blue Jays have covered the run line in seven of their last eight Wednesday home games against AL East opponents.
  • The Rays have trailed after 3 innings in six of their last eight road games against AL East opponents.

Why the Tampa Bay Rays will win

  • The Blue Jays have lost 10 of their last 11 home games against American League opponents.
  • The Rays have won seven of their last eight games against the Blue Jays.
  • The Blue Jays have failed to cover the run line in each of their last 12 games against American League opponents after playing the previous day.
  • The road team has covered the run line in nine of the Blue Jays’ last 10 games.
  • The Blue Jays have trailed after 5 innings in eight of their last nine home games against American League opponents.
  • The Blue Jays have trailed after 3 innings in each of their last five night games.

Total Runs Facts

  • Each of the last six games between the Rays and Blue Jays at Rogers Centre have gone OVER the total runs line.
  • Four of the Rays’ last five games after playing the previous day have gone OVER the total runs line.
  • There has been no run scored during the first inning in seven of the Blue Jays’ last eight games against American League opponents.
  • There has been no run scored during the first inning in seven of Griffin Jax’s last eight appearances as a starter.

Toronto Blue Jays Player Prop Facts

  • George Springer has hit a home run in three of his last five appearances in night games against AL teams that held a winning record.
  • Nathan Lukes has recorded at least one hit in each of his last nine appearances after playing the previous day.
  • Ernie Clement ranks 5th in the league in Hits (113) this season.

Tampa Bay Rays Player Prop Facts

  • Victor Mesa Jr. has hit a home run in four of his last five appearances.
  • Griffin Jax has recorded five or more strikeouts in each of his last six appearances in night games.
  • Griffin Jax has recorded a win in three of his last four appearances against opponents that held a losing record.
  • Nick Fortes has recorded at least one hit in each of his last seven appearances against the Blue Jays.
  • Yandy Diaz ranks 4th in the league in Hits (116) this season.

Matchup/League Facts

  • The Blue Jays rank 30th in the league for runs scored this season (400).
  • The Blue Jays rank 30th in the league for runs scored this season (400).
  • The Rays rank 1st in the league for strikeouts against this season (715).
  • The Rays rank 1st in the league for strikeouts against this season (715).

Blue Jays vs Rays Prediction 

Tampa Bay comes into this matchup looking for their third win in a row and they have scored 6+ runs in three of their last four. The Rays are 23-27 on the road this year, while the Blue Jays are 25-29 at home. Toronto has lost four of their last five games and they have scored a total of four runs in their last four games. The Blue Jays are starting Fisher, who will be an opener, while Jax has allowed 3+ earned runs in three of his last four starts. Take Toronto to get a bounce back win here. 

David Racey's Free Pick: Blue Jays ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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