Boston Red Sox vs Detroit Tigers Prediction 4/18/26 MLB Picks Today

The Detroit Tigers and the Boston Red Sox meet Wednesday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Detroit Tigers vs. Boston Red Sox prediction.

Starting Pitching Matchup

The Detroit Tigers will send out Tarik Skubal for the start here and Skubal is 2-2 with a 2.22 ERA and 23 strikeouts this season. In his last five starts against the Red Sox, Skubal is 2-2 with a 4.91 ERA and 31 strikeouts. Brayan Bello will start for Boston here and is 1-1 with a 6.14 ERA and 9 strikeouts this season. In his career, Bello is 0-1 with a 5.74 ERA and 14 strikeouts against Detroit.

Detroit Tigers Recap

The Detroit Tigers come into this game looking to bounce back from a 1-0 loss at the hands of Boston in Friday’s matchup to sit at 10-10 this season. After this series, Detroit will head home for a series against the Milwaukee Brewers.

Tigers Have Six-Game Win Streak Snapped

Colt Keith has 19 hits with 7 doubles and 5 RBIs while Kevin McGonigle’s added 22 hits with 6 doubles, 2 triples, a home run and 8 RBIs this season. Riley Greene has chipped in 18 hits with 6 doubles, a home run and 12 RBIs and Dillon Dingler’s added 15 hits with 3 doubles, 4 home runs and 14 RBIs. Kerry Carpenter also has 3 home runs and 10 RBIs so far this season.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to add on to their win over Detroit from Friday’s opener to sit at 8-11 this season. After this series, the Red Sox will renew their rivalry series against the New York Yankees.

Red Sox Win 6 Of Last 9

Wilyer Abreu leads the Red Sox with 22 hits including 4 doubles, a triple, 3 home runs and 10 RBIs while Trevor Story has 16 hits with 4 doubles, 2 homers and 17 RBIs and Marcelo Mayer’s added 9 hits with 3 doubles, a home run and 3 RBIs as well. Roman Anthony has 16 hits with 3 doubles, a triple, a home run and 3 RBIs so far this season while Jarren Duran has 11 hits with 3 doubles, a home run and 10 RBIs as well this season. Willson Contreras has added 17 hits with 2 doubles, 3 homers and 11 RBIs of his own on the year.

Detroit Tigers @ Boston Red Sox Betting Trends: April 18, 2026

• Probable Starting Pitcher: Brayan Bello      Record this season: 1-1      ERA: 6.14
• Home Record: 0-0
• Last 5 against Tigers: 0-1

Why the Boston Red Sox will win

• The home team has won each of the Tigers’ last 11 games.
• The Tigers have lost each of their last nine road games.
• The Tigers have failed to cover the run line in each of their last 13 games as favorites against American League opponents.
• The Red Sox have covered the run line in each of their last nine games as underdogs against AL Central opponents.
• The Red Sox have led after 3 innings in seven of their last eight day games against the Tigers at Fenway Park.
• The Tigers have trailed after 5 innings in each of their last five games as road favorites against American League opponents.

• Probable Starting Pitcher: Tarik Skubal      Record this season: 2-2      ERA: 2.22
• Road Record: 1-2
• Last 5 against Red Sox: 2-2

Why the Detroit Tigers will win

• The Tigers have won each of their last eight day games after going to extra innings.
• The Red Sox have lost each of their last four home games against American League opponents following a home win.
• The Red Sox have failed to cover the run line in each of their last seven home games against American League opponents.
• The road team has covered the run line in each of the last six games between the Tigers and Red Sox.
• The Tigers have led after 5 innings in seven of their last eight games as road favorites against AL East opponents.
• The Tigers have led after 3 innings in each of their last four day games against AL East opponents that held a losing record.
• The Red Sox have lost the first inning in six of their last seven games against American League opponents.

Total Runs Facts

• Seven of the Tigers’ last eight games as favorites against American League opponents have gone UNDER the total runs line.
• Each of the Red Sox’s last five home games against American League opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 13 of the Tigers’ last 14 games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Red Sox’s last nine day games against American League opponents.

Boston Red Sox Player Prop Facts

• Wilyer Abreu has hit a home run in three of his last eight appearances in day games.
• Trevor Story has recorded at least one hit in each of the Red Sox’s last eight games as underdogs.
• Willson Contreras ranks 8th amongst qualified players for On Base Percentage (.434) this season.

Detroit Tigers Player Prop Facts

• Spencer Torkelson has hit a home run in each of his last two appearances with the Tigers as favorites against the Red Sox.
• Tarik Skubal has recorded eight or more strikeouts in five of his last six appearances against AL opponents.
• Tarik Skubal has recorded a win in four of his last five appearances against AL East opponents that held a losing record.
• Javier Baez has recorded at least one hit in each of his last 11 road appearances against AL East opponents.

Matchup/League Facts

• The Red Sox rank T29th in the league for home runs this season (12).
• The Red Sox rank T27th in the league for steals this season (8).
• The Tigers rank 1st in the league for home runs allowed this season (12).
• The Tigers rank 29th in the league for steals this season (7).

Detroit Tigers vs. Boston Red Sox Prediction

I’m on the over in this game. The Detroit Tigers have a favorable matchup against Brayan Bello, who has been hittable at Fenway Park for the better part of his career. However, Tarik Skubal’s worst start last year came against these Red Sox and I think they can get to him for a few runs here to end up with a much higher-scoring game than Friday’s opener. Give me the over in this one.