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Red Sox vs Tigers Prediction 9/27/25 MLB Picks Today

Detroit Tigers (86-74) vs. Boston Red Sox (88-72)
September 27, 2025 4:10 pm EDT
The Line: Boston Red Sox / Detroit Tigers ; Over/Under:
(Get latest betting odds)

The Detroit Tigers and the Boston Red Sox meet Saturday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Red Sox vs Tigers Prediction.

Starting Pitching Matchup

The Detroit Tigers did not have a starting pitcher announced at the time that this article was posted. The Boston Red Sox will send out Connelly Early here and Early is 1-1 with a 1.88 ERA and 22 strikeouts this season. This will be Early’s first career start against Boston.

Detroit Tigers Recap

The Detroit Tigers come into this game looking to bounce back from a 4-3 loss at the hands of the Red Sox in Friday’s series opener to sit at 86-74 this season.

Tigers Drop 9 Of Their Last 10

Spencer Torkelson has 133 hits along with a .240 batting average including 31 home runs, 27 doubles and 78 RBIs. Kerry Carpenter also has 26 home runs and 62 RBIs while Riley Greene has 155 hits with 31 doubles, 36 home runs and 111 RBIs but also has a team-high 198 strikeouts as well this season. Dillon Dingler has 13 home runs and 57 RBIs and Zack McKinstry’s added 23 doubles, 11 triples, 12 home runs and 49 RBIs of his own along with 117 hits as well this season. Javier Baez has added 103 hits and 17 doubles as well as 11 home runs and 53 RBIs this season. Colt Keith also has 106 hits with 22 doubles, 13 home runs and 45 RBIs.

Why the Detroit Tigers will win

  • The Tigers have won 15 of their last 16 day games against American League opponents following a road loss.
  • The Red Sox have lost five of their last six day games against the Tigers at Fenway Park following a win.
  • The Tigers have covered the run line in 11 of their last 12 day games against AL East opponents that held a winning record.
  • The Red Sox have failed to cover the run line in seven of their last eight home games.

Detroit Tigers Player Prop Facts

  • Kerry Carpenter has hit a home run in three of his last four Saturday day appearances.
  • Parker Meadows has recorded at least one hit in each of his last 12 appearances against AL East opponents.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to add on to their series-opening W over the Tigers to improve to 88-72 this season.

Red Sox Clinch Playoff Spot

Alex Bregman has 117 hits including 27 doubles along with 18 home runs and 62 RBIs this season. Trevor Story’s added 161 hits with 25 home runs, 96 RBIs and 31 stolen bases while Jarren Duran has 157 hits with 40 doubles, 13 triples, 16 home runs, 82 RBIs and a team-high 24 stolen bases. Roman Anthony’s added 75 hits with 18 doubles, 8 home runs and 32 RBIs while Wilyer Abreu has 22 home runs with 69 RBIs and 6 stolen bases and Ceddanne Rafaela has 16 homers, 32 doubles, 3 triples, 62 RBIs and 19 stolen bases this season.

Why the Boston Red Sox will win

  • The home team has won each of the last six games between the Tigers and Red Sox.
  • The Tigers have lost nine of their last 10 games.
  • The Tigers have failed to cover the run line in seven of their last eight games following a loss.
  • The Red Sox have covered the run line in five of their last six day games against American League opponents that held a winning record.

Boston Red Sox Player Prop Facts

  • Alex Bregman has recorded at least one hit in 15 of his last 16 appearances in day games against AL Central teams that held a winning record.
  • Trevor Story has recorded a Double in three of the Red Sox’s last four day games.
  • Wilyer Abreu has hit a home run in each of his last two appearances in day games against AL Central teams that held a winning record.

Total Runs Facts

  • Eight of the Red Sox’s last nine games against AL Central opponents have gone OVER the total runs line.
  • Each of the Tigers’ last four road games after playing the previous day have gone UNDER the total runs line.

Red Sox vs Tigers Prediction

I’m on the Red Sox here. I know that the Red Sox have locked up a playoff spot and can’t really move up or down, so it’s in their best interest to stay healthy. However, the Tigers, despite being the more desperate team here, keep shooting themselves in the foot, and it’s hard to get behind them in any way shape or form given what they’ve done down the stretch. I’ll side with Boston here as a fade of Detroit more than anything else.

Chris Ruffolo's Free Pick: Boston Red Sox

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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