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Braves vs Cubs Prediction 9/10/25 MLB Picks Today

Chicago Cubs (82-63) vs. Atlanta Braves (65-80)
September 10, 2025 7:15 pm EDT
The Line: Atlanta Braves / Chicago Cubs; Over/Under:
(Get latest betting odds)

In this article we will formulate a Braves vs Cubs prediction for this MLB game on Wednesday, September 10th at Truist Park in Atlanta, Georgia. Let’s take a look at the prediction for this MLB matchup. 

Atlanta Braves Betting Preview

The Atlanta Braves are 65-80 this year after they split the first two games in this series by scores of 4-1 and 1-6. In their game two loss, Atlanta cut the deficit to 2-1 in the third inning, but failed to score over the last six innings in the defeat. The Braves recorded four hits and they committed one error in the game, while they were led by Profar, who went 1-4 with one RBI in the loss. Atlanta started Strider, who allowed six hits and two earned runs over 6.0 innings for the loss, while Diaz allowed three earned runs in relief. 

Prior to this series, the Braves lost two out of three against the Mariners and two out of three against the Cubs. Atlanta has lost three of their last four games and they are fourth in the NL East standings. The Atlanta pitching staff has a 4.45 ERA with a 1.31 WHIP and a .246 opponent batting average, while their offense has scored 631 runs with a .243 batting average and a .317 on base percentage this year. Matt Olson has led Atlanta with 23 home runs and 80 RBIs, while Marcell Ozuna has added 20 home runs and 62 RBIs this year. The projected starting pitcher for Atlanta is Chris Sale, who is 5-4 with a 2.38 ERA and a 1.10 WHIP over 102.0 innings pitched this year. 

Chicago Cubs Betting Preview

The Chicago Cubs are 82-63 this season after they won game two by a score of 6-1 on Tuesday night. Chicago led 2-0 early in the game and added four runs in the eighth to secure the victory. The Cubs recorded seven hits and they committed one error in the game, while they were led by Shaw and Crow-Armstrong, who both had two RBIs in the win. Chicago started Horton, who allowed four hits and one earned run over 6.1 innings for the win, while Kittredge picked up a hold. 

Prior to this series, the Cubs lost two out of three against the Nationals, but did win two out of three against the Braves before that. Chicago has lost four of their last six games and they are currently second in the NL Central standings. The Chicago pitching staff has a 3.87 ERA with a 1.19 WHIP and a .241 opponent batting average, while their offense has scored 710 runs with a .248 batting average and a .319 on base percentage this season. Seiya Suzuki has led Chicago with 27 home runs and 90 RBIs, while Pete Crow-Armstrong has added 28 home runs and 87 RBIs this year. The projected starting pitcher for Chicago is Jameson Taillon, who is 9-6 with a 4.15 ERA and a 1.08 WHIP over 106.1 innings pitched this season. 

Why the Braves will beat the Cubs

  • The Braves have won each of their last six home games against the Cubs following a loss.
  • The Cubs have lost seven of their last eight night games against the Braves following a win.
  • The Braves have covered the run line in each of their last eight games against National League opponents following a loss.
  • The Cubs have failed to cover the run line each of their last 10 Wednesday games against teams that held a losing record.
  • The Cubs have trailed after 5 innings in nine of their last 11 games at Truist Park against opponents that held a losing record.

Total Runs Facts

  • Each of the Braves’ last seven night games against National League opponents have gone UNDER the total runs line.
  • Seven of the Cubs’ last eight night games against NL East opponents have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cubs’ last four games at Truist Park.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Braves’ last four night games.

Atlanta Braves Player Prop Facts

  • Austin Riley has recorded at least one hit in each of his last 10 home appearances against NL Central opponents.
  • Chris Sale has recorded a win in three of his last four appearances against the Cubs.
  • Ozzie Albies has hit a home run in three of the Braves’ last four games against the Cubs.
  • Chris Sale has recorded nine or more strikeouts in four of his last five appearances.

Chicago Cubs Player Prop Facts

  • Kyle Tucker has recorded a Double in three of his last four road appearances.
  • Kyle Tucker has recorded at least one hit in 15 of his last 16 road appearances against opponents that held a losing record.
  • Ian Happ has hit at least one home run in three of the Cubs’ last six road games against NL East opponents.

Braves vs Cubs Prediction 

Chicago picked up a much needed win in game two of this series on Tuesday night, as they try to find some momentum ahead of the postseason. The Cubs are 38-35 on the road this year, while the Braves are 35-36 at home. Atlanta has allowed 35 runs in their last four games and they are starting Sale, who has allowed one earned run or fewer in four straight outings. The Cubs are going with Taillon, who has allowed two earned runs or fewer in three straight starts, but is coming off of the IL. I trust Sale on the mound here, so give me the Braves to win. 

David Racey's Free Pick: Braves ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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