Braves vs Nationals Prediction 4/22/26 MLB Picks Today

In this article, we will formulate a Braves vs Nationals Prediction for this MLB matchup on Wednesday, April 22^nd in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Washington Nationals Preview

The Washington Nationals have a 11-13 record this season and are sitting in the third place of the NL East. They have a 3-8 home record and are coming off an 11-4 home win against the Braves. Their previous three games were a 4-9 home loss against the Braves, a 3-0 home win, and a 6-7 home loss against the Giants.

The Nationals have a .253 batting average this season, .334 OBP and .404 Slugging percentage. Washington’s pitching staff has a 5.64 ERA and 1.53 WHIP. CJ Abrams is the team’s best hitter with a .296 batting average, also leading the team in RBI with 19. James Wood adds a team‑high 8 home runs.

Zack Littell (R) is the projected starting pitcher for the Nationals, and he has a 0-2 record, 7.11 ERA and 1.74 WHIP.

Atlanta Braves Preview

The Atlanta Braves have a 16-8 record this season and are sitting in the first place of the NL East. They have an 8-4 away record and are coming off a 4-11 road loss against the Nationals. Their previous three games were a 9-4 road win against the Nationals, and a 4-2 and a 3-1 road win against the Phillies.

The Braves have a .272 batting average this season, .340 OBP and .448 Slugging percentage. Atlanta’s pitching staff has a 3.04 ERA and 1.12 WHIP. Mauricio Dubon is the team’s best hitter with a .313 batting average. Drake Baldwin leads the team in RBI with 22, and Matt Olson adds a team‑high 6 home runs.

Martin Perez (L) is the projected starting pitcher for the Braves, and he has a 1-1 record, 2.21 ERA and 0.93 WHIP.

Atlanta Braves @ Washington Nationals Betting Trends: April 22, 2026

• Probable Starting Pitcher: Zack Littell      Record this season: 0-2      ERA: 7.11
• Home Record: 0-1
• Last 5 against Braves: 0-1

Why the Washington Nationals will win

• The Braves have lost each of their last three games as road favorites against the Nationals following a road loss.
• The Nationals have won each of their last four Wednesday night games as underdogs against the Braves.
• The Nationals have covered the run line in six of their last seven games against NL East opponents.
• The Braves have failed to cover the run line in each of their last four games against the Nationals following a road loss.
• The Nationals have won the first inning in four of their last five night games against opponents that held a winning record.
• The Nationals have led after 3 innings in each of their last five games against NL East opponents that held a winning record.
• The Nationals have led after 5 innings in each of their last four games.

• Probable Starting Pitcher: Martin Perez      Record this season: 1-1      ERA: 2.21
• Road Record: 1-0
• Last 5 against Nationals: 1-2

Why the Atlanta Braves will win

• The Nationals have lost each of their last seven home games following a win.
• The Braves have won 10 of their last 11 road games against NL East opponents that held a losing record.
• The Braves have covered the run line in each of their last nine night games against National League opponents following a road loss.
• The Nationals have failed to cover the run line in each of their last seven home games following a win.

Total Runs Facts

• Six of the last seven games between the Braves and Nationals at Nationals Park have gone OVER the total runs line.
• Twelve of the Braves’ last 16 games as road favorites have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Braves’ last eight games as road favorites.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Nationals’ last six games against NL East opponents.

Washington Nationals Player Prop Facts

• CJ Abrams has hit a home run in five of the Nationals’ last 10 night games against NL opponents that held a winning record.
• Keibert Ruiz has recorded at least one hit in each of his last seven appearances with the Nationals as home underdogs.
• Nasim Nunez ranks T2nd in the league in Steals (10) this season.

Atlanta Braves Player Prop Facts

• Matt Olson has hit a home run in six of the Braves’ last eight road games against the Nationals.
• Dominic Smith has recorded at least one hit in each of his last 13 appearances against NL East opponents.
• Drake Baldwin ranks T1st in the league in Hits (31) this season.

Matchup/League Facts

• The Nationals rank 1st in the league for runs scored this season (136).
• The Nationals rank 30th in the league for home runs allowed this season (42).
• The Braves rank 1st in the league for hits this season (226).
• The Braves rank 1st in the league for RBIs this season (132).

Braves vs Nationals Prediction

The Braves are 7-2 in their last 9 meetings against the Nationals and are 5-1 in their last 6 visits in Washington.

In this Braves vs Nationals Prediction, the Braves are coming as -150 road favorites. The Nats won yesterday’s game but the Braves once again have a serious pitching advantage, as Martin Perez goes up against a struggling Zack Littell, who has 11 earned runs in his last two starts. The Braves have the third-best offense and the 4^th-best bullpen, while the Nats are 26^th in bullpen ERA. I like the Braves in a bounce-back spot today, so take them on the moneyline on the road.