Cardinals vs Athletics Prediction 9/2/25 MLB Picks Today

The Athletics and St. Louis Cardinals meet Tuesday in MLB action at Busch Stadium. Here’s a Cardinals vs Athletics Prediction. This article will include a Cardinals vs Athletics Pick.

Athletics Betting Preview

The Athletics are 64-75 on the year and play the Angels, Red Sox, and Reds next. The Athletics are batting .254 on the season, have a .319 OBP, and a .434 slugging percentage. The Athletics pitching staff has a 4.82 ERA and a 1.37 WHIP. Brent Rooker leads the Athletics with 146 hits and 80 RBI, while Tyler Soderstrom and Jacob Wilson have combined for 264 hits and 136 RBI.

Luis Severino gets the ball for the Athletics, and he is 6-11 with a 4.82 ERA and 103 strikeouts this season. This will be Severino’s second career game against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 68-71 on the year and play the Giants, Mariners, and Brewers next. The St. Louis Cardinals are batting .247 on the season, have a .316 OBP, and a .383 slugging percentage. The St. Louis Cardinals pitching staff has a 4.30 ERA and a 1.31 WHIP. Alec Burleson leads the St. Louis Cardinals with 123 hits and 60 RBI while Masyn Winn and Brendan Donovan have combined for 239 hits and 96 RBI.

Miles Mikolas gets the ball for the St. Louis Cardinals, and he is 6-10 with a 5.04 ERA and 86 strikeouts this season. Mikolas is 0-1 with a 9.00 ERA and 5 strikeouts in his career against the Athletics.

Why the St. Louis Cardinals will win

• The Athletics have lost each of their last eight games as underdogs against National League opponents following a win.
• The Cardinals have won four of their last five games against AL West opponents following a home loss.
• The Athletics have failed to cover the run line in each of their last eight games as underdogs against National League opponents following a win.
• The Cardinals have covered the run line in four of their last five games as favorites against American League opponents.
• The Athletics have trailed after 3 innings in each of their last four night games against NL Central opponents.
• The Cardinals have led after 5 innings in four of their last five games as favorites against American League opponents.

Why the Athletics will win

• The Cardinals have lost each of their last eight home games against American League opponents.
• The Athletics have won each of their last six road games against teams that held a losing record.
• The Athletics have covered the run line each of their last eight road games against teams that held a losing record.
• The Cardinals have failed to cover the run line in each of their last seven games as home favorites against American League opponents.
• The Cardinals have lost the first inning in 10 of their last 11 night games against American League opponents.
• The Athletics have led after 3 innings in each of their last seven Tuesday games.
• The Cardinals have trailed after 5 innings in each of their last seven games as home favorites against American League opponents.

St. Louis Cardinals Player Prop Facts

• Willson Contreras has hit a home run in each of the Cardinals’ last two night games against AL opponents that held a losing record.
• Miles Mikolas has recorded four or more strikeouts in five of his last six home appearances against AL opponents that held a losing record.
• Brendan Donovan has recorded at least one hit in each of his last 11 Tuesday appearances against teams that held a losing record.
• Lars Nootbaar has recorded a Double in each of the Cardinals’ last four night games against AL West opponents that held a losing record.
• Victor Scott II ranks T9th in the league in Steals (31) this season.

Athletics Player Prop Facts

• Shea Langeliers has hit a home run in four of his last five appearances against opponents that held a losing record.
• Luis Severino has recorded four or more strikeouts in each of his last seven appearances against NL opponents that held a losing record.
• Brent Rooker has recorded at least one hit in each of the Athletics’ last nine games as underdogs against NL opponents.
• Zack Gelof has recorded at least one Double in four of his last five road appearances against opponents that held a losing record.
• Luis Severino has recorded a win in each of his last four appearances.
• Jacob Wilson ranks 2nd amongst qualified players for Batting Average (.318) this season.

Cardinals vs Athletics Prediction

The A’s have won four straight games with Severino on the mound, and while his season numbers are shaky, he has a 3.17 ERA and .214 allowed batting average in 65.1 road innings. Severino has been a solid pitcher this season when you take him out of Sacramento. Mikolas isn’t having a great season, and he’s coming off an August where he allowed 29 hits and 15 earned runs in 22.1 innings. In a battle between two bad teams with nothing to play for at this stage, I want the better pitcher. Give me the Athletics.